Sunshinevirus (taxid:1921703)

VIRION

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Enveloped, spherical.

GENOME

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Negative-stranded RNA linear genome, about 17 kb in size. Encodes for seven proteins.

GENE EXPRESSION

The viral RNA dependent RNA polymerase binds the encapsidated genome at the leader region, then sequentially transcribes each genes by recognizing start and stop signals flanking viral genes. mRNAs are capped and polyadenylated by the L protein during synthesis.

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Virus attaches to host cell surface receptors through F and G glycoproteins.
  2. Fusion with the plasma membrane; ribonucleocapsid is released in the cytoplasm.
  3. Sequential transcription, viral mRNAs are capped and polyadenylated in the cytoplasm.
  4. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  5. the ribonucleocapsid interacts with the matrix protein under the plasma membrane and buds via the ESCRT complex, releasing the virion.
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Sunshine Coast virus taxid:1195087

Protein ModelArchive
Fusion glycoprotein F0 ma-jd-viral-42790
Matrix ma-jd-viral-51415
Nucleoprotein (Nucleocapsid protein) ma-jd-viral-15237
Putative attachment protein ma-jd-viral-57191
Putative phosphoprotein ma-jd-viral-35153