Rotavirus

VIRION

Virion maturation schemes

Non enveloped, icosahedral, non-turreted virion with a triple capsid structure, about 80 nm in diameter. The intermediate capsid has a T=13 icosahedral symmetry, the inner capsid a T=2* icosahedral symmetry.

GENOME

Segmented linear dsRNA genome. Contains 11 segments coding for 12 proteins. Segments size range from 667 to 3,302nt (SiRV-A/SA11). Genome total size is 18,550 bp (SiRV-A/SA11). The viral mRNAs contain 5'-methylated cap structures but lack polyA tail. Instead, rotavirus mRNAs have at their 3' end a consensus sequence (UGACC) that is conserved in all 11 viral genes.
Co-infection of cells with different rotavirus strains belonging to the same serogroup A, B or C undergo mixing of the genome segments (genetic reassortment).

GENE EXPRESSION

The dsRNA genome is never completely uncoated, to prevent activation of antiviral state by the cell in response of dsRNA. The viral polymerase VP1 synthesizes a capped mRNA from each dsRNA segment. This capped mRNA is translocated to the cell cytoplasm where it is translated. NSP3 may act as a translation enhancer for viral gene expression.
Most segments are generally monocistronic. However, some segments encode more than one protein:
Segment 11 of rotaviruses A (but not rotaviruses C) encodes a second out-of-frame protein NSP6 by leaky scanning. Rotaviruses C NSP3 seems to produce two proteins by ribosomal skipping. Rotaviruses B segment 5 contains at least two potential ORFs. Segment 5 of the novel adult diarrhea virus, ADRV-N (nongroup A, B, C) may be cleaved into two products.

REPLICATION

CYTOPLASMIC

  1. Attachement of the viral VP4 protein to host receptors mediates clathrin-mediated endocytosis of the virus into the host cell.
  2. Particles are partially uncoated in endolysosomes (loss of the VP4-VP7 outermost layer), and penetrate into the cytoplasm via permeabilization of host endosomal membrane.
  3. Early transcription of the dsRNA genome by viral polymerase occurs inside these now double-layered particles (DLPs), so that dsRNA is never exposed to the cytoplasm. The nascent (+)RNAs are extruded into the cytoplasm and serve as template for viral proteins synthesis.
  4. Progeny cores with replicase activity are produced in cytoplasmic virus factories (also called viroplasms). This implies synthesis of complementary (-)RNA and initial steps of viral morphogenesis.
  5. Late transcription occurs in these progeny cores.
  6. At the periphery of virus factories, these core are coated with VP6, forming immature DLPs that bud across the membrane of the endoplasmic reticulum, acquiring a transient lipid membrane which is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the nonstructural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
  7. Mature virions are released presumably following cell death and associated breakdown of host plasma membrane.

Host-virus interaction

Innate immune response inhibition

Rotaviruses counteract many antiviral pathways in a strain-specific manner :
NSP1 protein induces the proteasome-dependent degradation of IRF3, IRF5, and IRF7 to prevent their induction of IFN .
NSP1 can also induce proteasome-dependent degradation of the ubiquitin ligase complex protein beta-TrCP, resulting in stabilization of IκB and repress NF-κB . .
Rotavirus can prevent STAT1 and STAT2 nuclear translocation .

Host gene expression shutoff by virus

NSP3 protein evicts cytoplasmic poly(A) binding protein (PABP) from translation initiation complexes and thus “shuts off the translation of cellular polyadenylated mRNAs”":/by_protein/1579. Inhibition of host poly(A)-binding protein by virus -> Host translation shutoff .

Replication cycle

Matching UniProtKB/Swiss-Prot entries

480 entries grouped by strain (browse by keywords)

All proteins are shown (view only 253 complete proteome entries)

12 entries

Rotavirus A (isolate RVA/Monkey/South Africa/SA11-H96/1958/G3P5B[2]) (RV-A) (Simian Agent 11 (isolate SI/South Africa/H96/58)) reference strain

Select_allDeselect_all
NSP2_ROTSH Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP1_ROTSH Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP3_ROTSH Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP5_ROTSH Non-structural protein 5 (NSP5) (NS26)
NSP6_ROTSH Non-structural protein 6 (NSP6)
NSP4_ROTSH Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
RDRP_ROTSH RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP2_ROTSH Inner capsid protein VP2
VP3_ROTSH Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP7_ROTSH Outer capsid glycoprotein VP7
VP6_ROTSH Intermediate capsid protein VP6
VP4_ROTSH Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

11 entries

Rotavirus C (isolate RVC/Human/United Kingdom/Bristol/1989) (RV-C) reference strain

Select_allDeselect_all
NSP5_ROTHC Non-structural protein 5 (NSP5)
NSP1_ROTHC Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP4_ROTHC Non-structural glycoprotein 4 (NSP4)
NSP3_ROTHC Non-structural protein 3 (NSP3) [Cleaved into: p38; p8]
NSP2_ROTHC Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
RDRP_ROTHC RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP4_ROTHC Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTHC Intermediate capsid protein VP6
VP7_ROTHC Outer capsid glycoprotein VP7
VP2_ROTHC Inner capsid protein VP2
VP3_ROTHC Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...

11 entries

Rotavirus X (strain RVX/Human/China/NADRV-J19/1997/GXP[X]) (RV ADRV-N) (Rotavirus (isolate novel adult diarrhea rotavirus-J19)) reference strain

Select_allDeselect_all
NSP4_ROTJ1 Non-structural glycoprotein 4 (NSP4)
NSP2_ROTJ1 Non-structural protein 2 (NSP2) (EC 3.6.4.-)
NSP1N_ROTJ1 Non-structural protein 1 (NSP1)
NSP5_ROTJ1 Non-structural protein 5 (NSP5)
NSP3_ROTJ1 Non-structural protein 3 (NSP3)
RDRP_ROTJ1 RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP3_ROTJ1 Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP6_ROTJ1 Intermediate capsid protein VP6
VP7_ROTJ1 Outer capsid glycoprotein VP7
VP2_ROTJ1 Inner capsid protein VP2
VP4_ROTJ1 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

12 entries

Rotavirus A (isolate RVA/Human/Belgium/B4106/2000/G3P11[14]) (RV-A) (Rotavirus A (isolate B4106))

Select_allDeselect_all
NSP1_ROT41 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP4_ROT41 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP2_ROT41 Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP5_ROT41 Non-structural protein 5 (NSP5) (NS26)
NSP6_ROT41 Non-structural protein 6 (NSP6)
NSP3_ROT41 Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
RDRP_ROT41 RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP6_ROT41 Intermediate capsid protein VP6
VP4_ROT41 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP2_ROT41 Inner capsid protein VP2
VP7_ROT41 Outer capsid glycoprotein VP7
VP3_ROT41 Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...

12 entries

Rotavirus A (isolate RVA/Human/United Kingdom/A64/1987/G10P11[14]) (RV-A)

Select_allDeselect_all
NSP4_ROTH7 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP6_ROTH7 Non-structural protein 6 (NSP6)
NSP2_ROTH7 Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP1_ROTH7 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP3_ROTH7 Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP5_ROTH7 Non-structural protein 5 (NSP5) (NS26)
RDRP_ROTH7 RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP2_ROTH7 Inner capsid protein VP2
VP6_ROTH7 Intermediate capsid protein VP6
VP3_ROTH7 Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP7_ROTH7 Outer capsid glycoprotein VP7
VP4_ROTH7 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

12 entries

Rotavirus A (isolate RVA/Human/United States/WI61/1983/G9P1A[8]) (RV-A)

Select_allDeselect_all
NSP3_ROTWI Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP5_ROTWI Non-structural protein 5 (NSP5) (NS26)
NSP2_ROTWI Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP1_ROTWI Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP6_ROTWI Non-structural protein 6 (NSP6)
NSP4_ROTWI Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
RDRP_ROTWI RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP4_ROTWI Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTWI Intermediate capsid protein VP6
VP7_ROTWI Outer capsid glycoprotein VP7
VP3_ROTWI Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP2_ROTWI Inner capsid protein VP2

12 entries

Rotavirus A (strain RVA/Cow/France/RF/1975/G6P6[1]) (RV-A)

Select_allDeselect_all
NSP2_ROTRF Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP1_ROTRF Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP6_ROTRF Non-structural protein 6 (NSP6)
NSP3_ROTRF Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP5_ROTRF Non-structural protein 5 (NSP5) (NS26)
NSP4_ROTRF Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
RDRP_ROTRF RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP4_ROTRF Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTRF Intermediate capsid protein VP6
VP7_ROTRF Outer capsid glycoprotein VP7
VP2_ROTRF Inner capsid protein VP2
VP3_ROTRF Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...

12 entries

Rotavirus A (strain RVA/Cow/United Kingdom/UK/1975/G6P7[5]) (RV-A)

Select_allDeselect_all
NSP1_ROTBU Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP3_ROTBU Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP4_ROTBU Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP2_ROTBU Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP5_ROTBU Non-structural protein 5 (NSP5) (NS26)
NSP6_ROTBU Non-structural protein 6 (NSP6)
RDRP_ROTBU RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP4_ROTBU Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP3_ROTBU Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP2_ROTBU Inner capsid protein VP2
VP6_ROTBU Intermediate capsid protein VP6
VP7_ROTBU Outer capsid glycoprotein VP7

12 entries

Rotavirus A (strain RVA/Cow/United States/WC3/1981/G6P7[5]) (RV-A) (Rotavirus (strain Wistar calf 3))

Select_allDeselect_all
NSP4_ROTW3 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP1_ROTW3 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP5_ROTW3 Non-structural protein 5 (NSP5) (NS26)
NSP2_ROTW3 Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP6_ROTW3 Non-structural protein 6 (NSP6)
NSP3_ROTW3 Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
RDRP_ROTW3 RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP2_ROTW3 Inner capsid protein VP2
VP4_ROTW3 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTW3 Intermediate capsid protein VP6
VP7_ROTW3 Outer capsid glycoprotein VP7
VP3_ROTW3 Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...

12 entries

Rotavirus A (strain RVA/Human/Indonesia/69M/1980/G8P4[10]) (RV-A)

Select_allDeselect_all
NSP1_ROTH6 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP3_ROTH6 Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP2_ROTH6 Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP5_ROTH6 Non-structural protein 5 (NSP5) (NS26)
NSP6_ROTH6 Non-structural protein 6 (NSP6)
NSP4_ROTH6 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
RDRP_ROTH6 RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP2_ROTH6 Inner capsid protein VP2
VP3_ROTH6 Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP4_ROTH6 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTH6 Outer capsid glycoprotein VP7
VP6_ROTH6 Intermediate capsid protein VP6

12 entries

Rotavirus A (strain RVA/Human/Japan/AU-1/1982/G3P3[9]) (RV-A)

Select_allDeselect_all
NSP5_ROTH3 Non-structural protein 5 (NSP5) (NS26)
NSP6_ROTH3 Non-structural protein 6 (NSP6)
NSP2_ROTH3 Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP3_ROTH3 Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP1_ROTH3 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP4_ROTH3 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
RDRP_ROTH3 RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP6_ROTH3 Intermediate capsid protein VP6
VP2_ROTH3 Inner capsid protein VP2
VP4_ROTH3 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP3_ROTH3 Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP7_ROTH3 Outer capsid glycoprotein VP7

12 entries

Rotavirus A (strain RVA/Human/Japan/KU/1995/G1P1A[8]) (RV-A)

Select_allDeselect_all
NSP5_ROTHK Non-structural protein 5 (NSP5) (NS26)
NSP1_ROTHK Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP2_ROTHK Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP3_ROTHK Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP6_ROTHK Non-structural protein 6 (NSP6)
NSP4_ROTHK Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
RDRP_ROTHK RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP6_ROTHK Intermediate capsid protein VP6
VP2_ROTHK Inner capsid protein VP2
VP7_ROTHK Outer capsid glycoprotein VP7
VP3_ROTHK Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP4_ROTHK Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

12 entries

Rotavirus A (strain RVA/Human/Philippines/L26/1987/G12P1B[4]) (RV-A)

Select_allDeselect_all
NSP1_ROTHL Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP6_ROTHL Non-structural protein 6 (NSP6)
NSP4_ROTHL Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP3_ROTHL Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP2_ROTHL Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP5_ROTHL Non-structural protein 5 (NSP5) (NS26)
RDRP_ROTHL RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP7_ROTHL Outer capsid glycoprotein VP7
VP4_ROTHL Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP3_ROTHL Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP2_ROTHL Inner capsid protein VP2
VP6_ROTHL Intermediate capsid protein VP6

12 entries

Rotavirus A (strain RVA/Human/United Kingdom/ST3/1975/G4P2A[6]) (RV-A) (Rotavirus A (strain St. Thomas 3))

Select_allDeselect_all
NSP1_ROTHT Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP3_ROTHT Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP2_ROTHT Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP5_ROTHT Non-structural protein 5 (NSP5) (NS26)
NSP6_ROTHT Non-structural protein 6 (NSP6)
NSP4_ROTHT Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
RDRP_ROTHT RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP2_ROTHT Inner capsid protein VP2
VP3_ROTHT Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP7_ROTHT Outer capsid glycoprotein VP7
VP4_ROTHT Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTHT Intermediate capsid protein VP6

12 entries

Rotavirus A (strain RVA/Human/United States/D/1974/G1P1A[8]) (RV-A)

Select_allDeselect_all
NSP2_ROTAD Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP6_ROTAD Non-structural protein 6 (NSP6)
NSP1_ROTAD Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP3_ROTAD Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP4_ROTAD Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP5_ROTAD Non-structural protein 5 (NSP5) (NS26)
RDRP_ROTAD RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP4_ROTAD Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP3_ROTAD Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP2_ROTAD Inner capsid protein VP2
VP6_ROTAD Intermediate capsid protein VP6
VP7_ROTAD Outer capsid glycoprotein VP7

12 entries

Rotavirus A (strain RVA/Human/United States/DS-1/1976/G2P1B[4]) (RV-A) (Rotavirus A (strain DS1))

Select_allDeselect_all
NSP2_ROTHD Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP3_ROTHD Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP1_ROTHD Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP5_ROTHD Non-structural protein 5 (NSP5) (NS26)
NSP6_ROTHD Non-structural protein 6 (NSP6)
NSP4_ROTHD Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
RDRP_ROTHD RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP2_ROTHD Inner capsid protein VP2
VP3_ROTHD Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP4_ROTHD Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTHD Intermediate capsid protein VP6
VP7_ROTHD Outer capsid glycoprotein VP7

12 entries

Rotavirus A (strain RVA/Human/United States/P/1974/G3P1A[8]) (RV-A)

Select_allDeselect_all
NSP2_ROTHP Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP5_ROTHP Non-structural protein 5 (NSP5) (NS26)
NSP6_ROTHP Non-structural protein 6 (NSP6)
NSP4_ROTHP Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP3_ROTHP Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP1_ROTHP Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
RDRP_ROTHP RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP2_ROTHP Inner capsid protein VP2
VP3_ROTHP Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP4_ROTHP Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTHP Intermediate capsid protein VP6
VP7_ROTHP Outer capsid glycoprotein VP7

12 entries

Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) (RV-A)

Select_allDeselect_all
NSP1_ROTHW Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP5_ROTHW Non-structural protein 5 (NSP5) (NS26)
NSP6_ROTHW Non-structural protein 6 (NSP6)
NSP2_ROTHW Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP3_ROTHW Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP4_ROTHW Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
RDRP_ROTHW RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP2_ROTHW Inner capsid protein VP2
VP4_ROTHW Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP3_ROTHW Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP6_ROTHW Intermediate capsid protein VP6
VP7_ROTHW Outer capsid glycoprotein VP7

12 entries

Rotavirus A (strain RVA/SA11-Both/G3P5B[2]) (RV-A) (Simian Agent 11 (strain Both))

Select_allDeselect_all
NSP3_ROTS1 Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP4_ROTS1 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP1_ROTS1 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP5_ROTS1 Non-structural protein 5 (NSP5) (NS26)
NSP6_ROTS1 Non-structural protein 6 (NSP6)
NSP2_ROTS1 Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
RDRP_ROTS1 RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP4_ROTS1 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP2_ROTS1 Inner capsid protein VP2
VP7_ROTS1 Outer capsid glycoprotein VP7
VP6_ROTS1 Intermediate capsid protein VP6
VP3_ROTS1 Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...

11 entries

Rotavirus C (strain RVC/Pig/United States/Cowden/1980) (RV-C)

Select_allDeselect_all
NSP3_ROTPC Non-structural protein 3 (NSP3) [Cleaved into: p38; p8]
NSP4_ROTPC Non-structural glycoprotein 4 (NSP4)
NSP1_ROTPC Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP5_ROTPC Non-structural protein 5 (NSP5)
NSP2_ROTPC Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
RDRP_ROTPC RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP2_ROTPC Inner capsid protein VP2
VP3_ROTPC Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP6_ROTPC Intermediate capsid protein VP6
VP7_ROTPC Outer capsid glycoprotein VP7
VP4_ROTPC Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

11 entries

Rotavirus X (isolate RVX/Human/Bangladesh/NADRV-B219/2002/GXP[X]) (RV ADRV-N) (Rotavirus (isolate novel adult diarrhea rotavirus-B219))

Select_allDeselect_all
NSP1N_ROTB2 Non-structural protein 1 (NSP1)
NSP5_ROTB2 Non-structural protein 5 (NSP5)
NSP2_ROTB2 Non-structural protein 2 (NSP2) (EC 3.6.4.-)
NSP4_ROTB2 Non-structural glycoprotein 4 (NSP4)
NSP3_ROTB2 Non-structural protein 3 (NSP3)
RDRP_ROTB2 RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP3_ROTB2 Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP7_ROTB2 Outer capsid glycoprotein VP7
VP6_ROTB2 Intermediate capsid protein VP6
VP2_ROTB2 Inner capsid protein VP2
VP4_ROTB2 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

10 entries

Rotavirus B (isolate RVB/Human/China/ADRV/1982) (RV-B) (Rotavirus B (isolate adult diarrhea rotavirus))

Select_allDeselect_all
NSP2_ROTGA Non-structural protein 2 (NSP2) (EC 3.6.4.-)
NSP4_ROTGA Non-structural glycoprotein 4 (NSP4)
NSP5_ROTGA Non-structural protein 5 (NSP5)
NSP1B_ROTGA Non-structural protein 1, peptide 2 (NSP1 peptide 2) (NSP1-2)
NSP3_ROTGA Non-structural protein 3 (NSP3)
NSP1A_ROTGA Non-structural protein 1, peptide 1 (NSP1 peptide 1) (NSP1-1)
VP4_ROTGA Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP2_ROTGA Inner capsid protein VP2
VP6_ROTGA Intermediate capsid protein VP6
VP7_ROTGA Outer capsid glycoprotein VP7

9 entries

Rotavirus A (strain RVA/Cow/United States/NCDV-Lincoln/1969/G6P6[1]) (RV-A) (Rotavirus A (strain Nebraska calf diarrhea virus))

Select_allDeselect_all
NSP3_ROTBN Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP2_ROTBN Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP4_ROTBN Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
RDRP_ROTBN RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP2_ROTBN Inner capsid protein VP2
VP3_ROTBN Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP7_ROTBN Outer capsid glycoprotein VP7
VP4_ROTBN Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTBN Intermediate capsid protein VP6

9 entries

Rotavirus A (strain RVA/Pig/United States/OSU/1977/G5P9[7]) (RV-A) (Rotavirus A (strain Ohio State University))

Select_allDeselect_all
NSP1_ROTP5 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP4_ROTP5 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP5_ROTP5 Non-structural protein 5 (NSP5) (NS26)
NSP3_ROTP5 Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP2_ROTP5 Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
VP7_ROTP5 Outer capsid glycoprotein VP7
VP4_ROTP5 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP3_ROTP5 Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP6_ROTP5 Intermediate capsid protein VP6

8 entries

Rotavirus A (strain RVA/Pig/Mexico/YM/1983/G11P9[7]) (RV-A)

Select_allDeselect_all
NSP1_ROTPY Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP4_ROTPY Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP6_ROTPY Non-structural protein 6 (NSP6)
NSP5_ROTPY Non-structural protein 5 (NSP5) (NS26)
RDRP_ROTPY RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP7_ROTPY Outer capsid glycoprotein VP7
VP4_ROTPY Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTPY Intermediate capsid protein VP6

8 entries

Rotavirus B (isolate RVB/Rat/United States/IDIR/1984/G1P[X]) (RV-B) (Rotavirus B (isolate infectious diarrhea of infant rats))

Select_allDeselect_all
NSP1A_ROTGI Non-structural protein 1, peptide 1 (NSP1 peptide 1) (NSP1-1)
NSP1B_ROTGI Non-structural protein 1, peptide 2 (NSP1 peptide 2) (NSP1-2)
NSP5_ROTGI Non-structural protein 5 (NSP5)
RDRP_ROTGI RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP4_ROTGI Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTGI Intermediate capsid protein VP6
VP7_ROTGI Outer capsid glycoprotein VP7
VP2_ROTGI Inner capsid protein VP2

7 entries

Rotavirus A (strain RVA/Human/Japan/S2/1980/G2P1B[4]) (RV-A)

Select_allDeselect_all
NSP3_ROTHS Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP4_ROTHS Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
RDRP_ROTHS RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP6_ROTHS Intermediate capsid protein VP6
VP2_ROTHS Inner capsid protein VP2
VP7_ROTHS Outer capsid glycoprotein VP7
VP3_ROTHS Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...

7 entries

Rotavirus A (strain RVA/Human/Japan/YO/1977/G3P1A[8]) (RV-A)

Select_allDeselect_all
NSP4_ROTYO Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
RDRP_ROTYO RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP4_ROTYO Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTYO Intermediate capsid protein VP6
VP2_ROTYO Inner capsid protein VP2
VP7_ROTYO Outer capsid glycoprotein VP7
VP3_ROTYO Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...

7 entries

Rotavirus A (strain RVA/Monkey/United States/RRV/1980/G3P5B[3]) (RV-A)

Select_allDeselect_all
NSP1_ROTRH Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP5_ROTRH Non-structural protein 5 (NSP5) (NS26)
NSP3_ROTRH Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP6_ROTRH Non-structural protein 6 (NSP6)
VP7_ROTRH Outer capsid glycoprotein VP7
VP4_ROTRH Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTRH Intermediate capsid protein VP6

6 entries

Rotavirus A (isolate RVA/Monkey/United States/TUCH/2003/G3P[24]) (RV-A)

Select_allDeselect_all
NSP1_ROTTU Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
RDRP_ROTTU RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP2_ROTTU Inner capsid protein VP2
VP4_ROTTU Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTTU Intermediate capsid protein VP6
VP3_ROTTU Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...

6 entries

Rotavirus C (isolate RVC/Cow/Japan/Shintoku/1991/G2P[3]) (RV-C)

Select_allDeselect_all
NSP3_ROTBS Non-structural protein 3 (NSP3) [Cleaved into: p38; p8]
NSP5_ROTBS Non-structural protein 5 (NSP5)
VP3_ROTBS Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP6_ROTBS Intermediate capsid protein VP6
VP7_ROTBS Outer capsid glycoprotein VP7
VP4_ROTBS Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

5 entries

Rotavirus A (isolate RVA/Cow/United States/B223/1983/G10P8[11 ]) (RV-A)

Select_allDeselect_all
NSP1_ROTBB Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP4_ROTBB Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP6_ROTBB Intermediate capsid protein VP6
VP7_ROTBB Outer capsid glycoprotein VP7
VP4_ROTBB Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

5 entries

Rotavirus A (isolate RVA/Equine/United Kingdom/L338/1988/G13P12[18]) (RV-A)

Select_allDeselect_all
NSP1_ROTEL Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
VP4_ROTEL Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP3_ROTEL Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP6_ROTEL Intermediate capsid protein VP6
VP7_ROTEL Outer capsid glycoprotein VP7

5 entries

Rotavirus A (strain RVA/Pig/United States/Gottfried/1983/G4P2B[6]) (RV-A)

Select_allDeselect_all
NSP1_ROTPG Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
RDRP_ROTPG RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)
VP4_ROTPG Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTPG Intermediate capsid protein VP6
VP7_ROTPG Outer capsid glycoprotein VP7

5 entries

Rotavirus A (strain RVA/Rabbit/United States/ALA/XXXX/G3P11[14]) (RV-A) (Rotavirus A (strain Alabama))

Select_allDeselect_all
NSP5_ROTRA Non-structural protein 5 (NSP5) (NS26)
NSP1_ROTRA Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP6_ROTRA Non-structural protein 6 (NSP6)
NSP4_ROTRA Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP4_ROTRA Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

4 entries

Rotavirus A (isolate RVA/Cow/South/Africa/Offal agent/1965/G8P6[1]) (RV-A)

Select_allDeselect_all
NSP2_ROTAP Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP1_ROTAP Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
VP4_ROTAP Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTAP Outer capsid glycoprotein VP7

4 entries

Rotavirus A (isolate RVA/Equine/United Kingdom/H2/1976/G3P4[12]) (RV-A) (Rotavirus A (isolate H-2))

Select_allDeselect_all
NSP4_ROTEH Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP1_ROTEH Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
VP4_ROTEH Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTEH Intermediate capsid protein VP6

4 entries

Rotavirus A (isolate RVA/Human/India/116E/1986/G9P8[11]) (RV-A)

Select_allDeselect_all
NSP1_ROTHU Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
VP4_ROTHU Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTHU Outer capsid glycoprotein VP7
VP6_ROTHU Intermediate capsid protein VP6

4 entries

Rotavirus A (isolate RVA/Mouse/Brazil/EHP/1981/G16P[20]) (RV-A)

Select_allDeselect_all
NSP4_ROTME Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP1_ROTME Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
VP4_ROTME Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTME Outer capsid glycoprotein VP7

4 entries

Rotavirus A (strain RVA/Human/Japan/K8/1977/G1P3A[9]) (RV-A)

Select_allDeselect_all
NSP1_ROTHJ Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP5_ROTHJ Non-structural protein 5 (NSP5) (NS26)
VP4_ROTHJ Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTHJ Outer capsid glycoprotein VP7

4 entries

Rotavirus A (strain RVA/Human/United States/M/1976/G3P[X]) (RV-A)

Select_allDeselect_all
NSP5_ROTAM Non-structural protein 5 (NSP5) (NS26)
NSP4_ROTAM Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP3_ROTAM Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
VP7_ROTAM Outer capsid glycoprotein VP7

4 entries

Rotavirus A (strain RVA/Human/Venezuela/M37/1982/G1P2A[6]) (RV-A)

Select_allDeselect_all
NSP4_ROTHM Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP1_ROTHM Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
VP4_ROTHM Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTHM Outer capsid glycoprotein VP7

4 entries

Rotavirus A (strain RVA/Turkey/Ireland/Ty-1/1978/G7P[17]) (RV-A)

Select_allDeselect_all
NSP2_ROTA1 Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP4_ROTA1 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP6_ROTA1 Intermediate capsid protein VP6
VP7_ROTA1 Outer capsid glycoprotein VP7

3 entries

Rotavirus A (isolate RVA/Cat/Japan/FRV64/1989/G3P5B[3]) (RV-A)

Select_allDeselect_all
NSP1_ROTF6 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
NSP4_ROTF6 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP4_ROTF6 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

3 entries

Rotavirus A (isolate RVA/Cow/Germany/993/1983/G18P[17]) (RV-A)

Select_allDeselect_all
VP7_ROTB9 Outer capsid glycoprotein VP7
VP4_ROTB9 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTB9 Intermediate capsid protein VP6

3 entries

Rotavirus A (isolate RVA/Cow/India/Hg18/2000/G15P[21]) (RV-A)

Select_allDeselect_all
NSP4_ROT18 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP4_ROT18 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROT18 Outer capsid glycoprotein VP7

3 entries

Rotavirus A (isolate RVA/Cow/Thailand/A44/1988/G10P8[11]) (RV-A)

Select_allDeselect_all
NSP1_ROTBA Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
VP4_ROTBA Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTBA Outer capsid glycoprotein VP7

3 entries

Rotavirus A (isolate RVA/Cow/United States/VMRI/1988/G6P[5]) (RV-A)

Select_allDeselect_all
NSP5_ROTBV Non-structural protein 5 (NSP5) (NS26)
VP4_ROTBV Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTBV Outer capsid glycoprotein VP7

3 entries

Rotavirus A (isolate RVA/Dog/United States/K9/1981/G3P5A[3]) (RV-A)

Select_allDeselect_all
NSP1_ROTD9 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
VP4_ROTD9 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTD9 Outer capsid glycoprotein VP7

3 entries

Rotavirus A (isolate RVA/Equine/Japan/HO-5/1980/G3P[X]) (RV-A)

Select_allDeselect_all
VP7_ROTEO Outer capsid glycoprotein VP7
VP4_ROTEO Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTEO Intermediate capsid protein VP6

3 entries

Rotavirus A (isolate RVA/Equine/United States/FI-23/1981/G14P4[12]) (RV-A) (Rotavirus A (strain FI23))

Select_allDeselect_all
NSP4_ROTE2 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP6_ROTE2 Intermediate capsid protein VP6
VP7_ROTE2 Outer capsid glycoprotein VP7

3 entries

Rotavirus A (isolate RVA/Human/Italy/VA70/1975/G4P1A[8]) (RV-A)

Select_allDeselect_all
NSP4_ROTHV Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP7_ROTHV Outer capsid glycoprotein VP7
VP4_ROTHV Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

3 entries

Rotavirus A (isolate RVA/Human/Sweden/1076/1983/G2P2A[6]) (RV-A)

Select_allDeselect_all
NSP4_ROTH1 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP4_ROTH1 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTH1 Intermediate capsid protein VP6

3 entries

Rotavirus A (isolate RVA/Mouse/United States/Eb/1982/G16P10[16]) (RV-A)

Select_allDeselect_all
NSP4_ROTMB Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP7_ROTMB Outer capsid glycoprotein VP7
VP4_ROTMB Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

3 entries

Rotavirus A (isolate RVA/Pig/Australia/CRW-8/1987/G3P9[7]) (RV-A)

Select_allDeselect_all
VP7_ROTP3 Outer capsid glycoprotein VP7
VP4_ROTP3 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP6_ROTP3 Intermediate capsid protein VP6

3 entries

Rotavirus A (strain RVA/Chicken/Ireland/Ch2/1979/G7P[X]) (RV-A) (Rotavirus A (strain Ch-2))

Select_allDeselect_all
VP7_ROTCC Outer capsid glycoprotein VP7
VP3_ROTCC Protein VP3 [Includes: mRNA guanylyltransferase (EC 2.7.7.50); mRNA ...
VP6_ROTCC Intermediate capsid protein VP6

3 entries

Rotavirus A (strain RVA/Cow/United States/B641/XXXX/G6P7[5]) (RV-A)

Select_allDeselect_all
NSP1_ROTB4 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
VP4_ROTB4 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTB4 Outer capsid glycoprotein VP7

3 entries

Rotavirus A (strain RVA/Equine/United States/FI-14/1980/G3P4[12]) (RV-A) (Rotavirus A (strain FI14))

Select_allDeselect_all
NSP4_ROTE1 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP6_ROTE1 Intermediate capsid protein VP6
VP4_ROTE1 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

3 entries

Rotavirus A (strain RVA/Human/Australia/RV-5/1981/G2P1B[4]) (RV-A) (Rotavirus A (strain RV5))

Select_allDeselect_all
NSP4_ROTH5 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
NSP5_ROTH5 Non-structural protein 5 (NSP5) (NS26)
VP4_ROTH5 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

3 entries

Rotavirus A (strain RVA/Human/Indonesia/B37/XXXX/G8P[X]) (RV-A)

Select_allDeselect_all
NSP5_ROTHB Non-structural protein 5 (NSP5) (NS26)
NSP6_ROTHB Non-structural protein 6 (NSP6)
VP7_ROTHB Outer capsid glycoprotein VP7

3 entries

Rotavirus A (strain RVA/Human/Japan/MO/1982/G3P1A[8]) (RV-A)

Select_allDeselect_all
NSP4_ROTHO Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP4_ROTHO Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTHO Outer capsid glycoprotein VP7

3 entries

Rotavirus A (strain RVA/SA11-4F/G3P6[1]) (RV-A) (Simian Agent 11 (strain 4F))

Select_allDeselect_all
NSP3_ROTS4 Non-structural protein 3 (NSP3) (NCVP4) (Non-structural RNA-binding protein 34) (NS34)
NSP1_ROTS4 Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
VP4_ROTS4 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

3 entries

Rotavirus A (strain RVA/SA11-Patton/G3P[X]) (RV-A) (Simian Agent 11 (strain Patton))

Select_allDeselect_all
NSP2_ROTSP Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
NSP1_ROTSP Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
RDRP_ROTSP RNA-directed RNA polymerase (EC 2.7.7.48) (Protein VP1)

3 entries

Rotavirus A (strain RVA/SA11-Ramig/G3P[X]) (RV-A) (Simian Agent 11 (strain Ramig))

Select_allDeselect_all
NSP2_ROTSR Non-structural protein 2 (NSP2) (EC 3.6.4.-) (NCVP3) (Non-structural RNA-binding protein 35) (NS35)
VP6_ROTSR Intermediate capsid protein VP6
VP2_ROTSR Inner capsid protein VP2

2 entries

Rotavirus A (isolate RVA/Cow/Japan/KK3/1983/G10P8[11]) (RV-A)

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VP4_ROTBK Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTBK Outer capsid glycoprotein VP7

2 entries

Rotavirus A (isolate RVA/Cow/Thailand/61A/1988/G10P7[5]) (RV-A)

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VP4_ROTB6 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTB6 Outer capsid glycoprotein VP7

2 entries

Rotavirus A (isolate RVA/Cow/Thailand/A5/1988/G8P6[1]) (RV-A)

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VP7_ROTB5 Outer capsid glycoprotein VP7
VP4_ROTB5 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

2 entries

Rotavirus A (isolate RVA/Dog/United States/Cu-1/1982/G3P5A[3]) (RV-A)

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NSP4_ROTCU Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP4_ROTCU Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

2 entries

Rotavirus A (isolate RVA/Human/Thailand/Mc35/1992/G10P11[14]) (RV-A)

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VP4_ROTHQ Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...
VP7_ROTHQ Outer capsid glycoprotein VP7

2 entries

Rotavirus A (isolate RVA/Pig/Venezuela/A46/1985/G5P13[13]) (RV-A)

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VP7_ROT46 Outer capsid glycoprotein VP7
VP4_ROT46 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

2 entries

Rotavirus A (strain RVA/Human/Australia/RV-4/1977/G1P1A[8]) (RV-A) (Rotavirus A (strain RV4))

Select_allDeselect_all
NSP4_ROTH4 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP7_ROTH4 Outer capsid glycoprotein VP7

2 entries

Rotavirus A (strain RVA/Human/Japan/KUN/1980/G2P1B[4]) (RV-A)

Select_allDeselect_all
NSP4_ROTKU Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)
VP7_ROTKU Outer capsid glycoprotein VP7

2 entries

Rotavirus A (strain RVA/SA11-FEM/G3P6[1]) (RV-A) (Simian Agent 11 (strain FEM))

Select_allDeselect_all
NSP1_ROTSF Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)
VP4_ROTSF Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

1 entry

Rotavirus A (isolate RVA/Cat/Japan/FRV-1/1986/G3P3[9]) (RV-A) (Rotavirus A (isolate FRV1))

VP4_ROTF1 Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

1 entry

Rotavirus A (isolate RVA/Cow/Argentina/T449/1992/G1P[X]) (RV-A)

VP7_ROTBT Outer capsid glycoprotein VP7

1 entry

Rotavirus A (isolate RVA/Cow/Japan/KN-4/1983/G6P8[11]) (RV-A)

VP7_ROTBJ Outer capsid glycoprotein VP7

1 entry

Rotavirus A (isolate RVA/Human/-/RK9/XXXX/GXP[X]) (RV-A)

VP7_ROTH9 Outer capsid glycoprotein VP7

1 entry

Rotavirus A (isolate RVA/Human/Australia/A91a/1991/G1P[X]) (RV-A)

VP7_ROTHX Outer capsid glycoprotein VP7

1 entry

Rotavirus A (isolate RVA/Human/Australia/Hu5/1977/G2P[X]) (RV-A) (Rotavirus A (isolate Hu/5))

VP7_ROTHA Outer capsid glycoprotein VP7

1 entry

Rotavirus A (isolate RVA/Human/Australia/McN13/1980/G3P2A[6]) (RV-A)

VP4_ROTHN Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

1 entry

Rotavirus A (isolate RVA/Human/Israel/RO1845/1993/G3P5A[3]) (RV-A)

VP4_ROTHY Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

1 entry

Rotavirus A (isolate RVA/Human/Japan/IGV-80-3/XXXX/GXP[X]) (RV-A)

NSP1_ROTHI Non-structural protein 1 (NSP1) (NCVP2) (Non-structural RNA-binding protein 53) (NS53)

1 entry

Rotavirus A (isolate RVA/Pig/Australia/AT/1976/G3P9[7]) (RV-A) (Rotavirus A (isolate AT/76))

VP7_ROTP2 Outer capsid glycoprotein VP7

1 entry

Rotavirus A (isolate RVA/Pig/Australia/BEN144/1989/G4P2B[6]) (RV-A)

VP7_ROTPB Outer capsid glycoprotein VP7

1 entry

Rotavirus A (isolate RVA/Pig/Australia/BMI-1/1989/G4P9[7]) (RV-A)

VP7_ROTPM Outer capsid glycoprotein VP7

1 entry

Rotavirus A (isolate RVA/Pig/Australia/TFR-41/1987/G5P9[7]) (RV-A)

VP7_ROTP6 Outer capsid glycoprotein VP7

1 entry

Rotavirus A (isolate RVA/Sheep/China/lp14/1981/G10P[15]) (RV-A)

VP6_ROTLP Intermediate capsid protein VP6

1 entry

Rotavirus A (strain RVA/Cow/Canada/C486/1977/G6P6[1]) (RV-A)

VP4_ROTBC Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

1 entry

Rotavirus A (strain RVA/Human/United Kingdom/A28/1987/G10P[X]) (RV-A)

NSP4_ROTH2 Non-structural glycoprotein 4 (NSP4) (NCVP5) (NS28)

1 entry

Rotavirus A (strain RVA/Human/Venezuela/HN126/1983/G2P[X]) (RV-A) (Rotavirus A (strain HN-126))

VP7_ROTHH Outer capsid glycoprotein VP7

1 entry

Rotavirus A (strain RVA/Pig/Russia/K/1987) (RV-A)

VP7_ROTPK Outer capsid glycoprotein VP7

1 entry

Rotavirus A (strain RVA/SA11-SEM/G3P5B[2]) (RV-A) (Simian Agent 11 (strain SEM))

VP4_ROTSS Outer capsid protein VP4 (Hemagglutinin) [Cleaved into: Outer capsid protein VP8*; Outer capsid ...

1 entry

Rotavirus C (isolate RVC/Human/Brazil/Belem/1992) (RV-C)

VP6_ROTHF Intermediate capsid protein VP6

1 entry

Rotavirus C (isolate RVC/Human/Japan/88-220/1988) (RV-C)

VP7_ROTHE Outer capsid glycoprotein VP7

1 entry

Rotavirus C (isolate RVC/Human/United Kingdom/Preston/1992) (RV-C)

VP6_ROTHG Intermediate capsid protein VP6