H1N1 subtype

VIRION

Molecular biology

Enveloped. Usually rounded but can be filamentous. The virions are 80-120 nm in diameter.

GENOME

Segmented ssRNA(-) linear genome, encapsidated by nucleoprotein (NP). Contains 8 segments coding for 12-14 proteins depending on strains. Segments size range from 890 to 2,341nt. Genome total size is 13.5Kb

GENE EXPRESSION

Viral RNA polymerase (PB1, PB2 and PA) transcribes one mRNA from each genome segment. Transcription is primed by cap cleaved from cellular mRNAS by Cap snatching. mRNA are polyadenylated by the viral polymerase stuttering on a poly U track. MP and NS mRNA can be alternately spliced, giving rise to mRNA coding for M2 and NEP proteins. Some strains can express M42 from the M segment . PB1 mRNA encode three proteins by leaky scanning: PB1, N40 and PB1-F2 . Pa-X protein is translated by ribosomal frameshift on the PA gene. Leaky scanning may produces N-truncated PA proteins, namely PA-N155 and PA-N182 . PB2-S1 would be an alternative splicing from PB2 gene (unpublished 1/1/15).

REPLICATION

NUCLEUS

  1. Virus attaches to sialic acid receptor though HA protein and is endocytosed by clathrins in the host cell.
  2. endosome acidification induces fusion of virus membrane with the vesicle membrane; encapsidated RNA segments migrate to the nucleus.
  3. Transcription of genomic segments by the viral polymerase produces mRNAs that are capped and polyadenylated by the viral polymerase.
  4. Replication of genomic segments.
  5. High level of M1 protein induces genomes segments export from nucleus by NEP protein.
  6. Virus assembly and budding occurs at the plasma membrane.

Host-virus interaction

Innate immune response inhibition

Influenza A virus inhibits the cascade leading to production of interferon-beta by targeting different cellular proteins. NS1 inhibits host RIG-I activation upon recognition of viral RNA, and subsequent induction of IFN-beta expression.

PB1-F2 inhibits host MAVS activation.

Host protein shutoff

NS1 induces host gene expression shutoff by inducing host mRNA suppression through polyadenlyation inhibition. The viral mRNA are not affected because their polyA tail is generated by polymerase stuttering.

Matching UniProtKB/Swiss-Prot entries

338 entries grouped by protein (browse by keywords)

All proteins are shown (view only 236 complete proteome entries)

30 entries

Hemagglutinin

Select_allDeselect_all
HEMA_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
HEMA_I00A1
Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
HEMA_I06A0
Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
HEMA_I07A0
Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)
HEMA_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
HEMA_I30A0
Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)
HEMA_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
HEMA_I35A3
Influenza A virus (strain A/USA:Phila/1935 H1N1)
HEMA_I36A0
Influenza A virus (strain A/Henry/1936 H1N1)
HEMA_I40A0
Influenza A virus (strain A/Hickox/1940 H1N1)
HEMA_I43A0
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
HEMA_I45A0
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
HEMA_I51A0
Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
HEMA_I54A0
Influenza A virus (strain A/Leningrad/1/1954 H1N1)
HEMA_I54A2
Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
HEMA_I61A1
Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
HEMA_I67A2
Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)
HEMA_I76A4
Influenza A virus (strain A/Duck/Alberta/35/1976 H1N1)
HEMA_I76AI
Influenza A virus (strain A/Swine/New Jersey/11/1976 H1N1)
HEMA_I77AA
Influenza A virus (strain A/Brazil/11/1978 H1N1)
HEMA_I77AB
Influenza A virus (strain A/USSR/90/1977 H1N1)
HEMA_I79A4
Influenza A virus (strain A/Kiev/59/1979 H1N1)
HEMA_I80A1
Influenza A virus (strain A/Duck/Australia/749/1980 H1N1)
HEMA_I80AA
Influenza A virus (strain A/India/6263/1980 H1N1)
HEMA_I81A3
Influenza A virus (strain A/Turkey/Minnesota/1661/1981 H1N1)
HEMA_I83A1
Influenza A virus (strain A/Chile/1/1983 H1N1)
HEMA_I85A4
Influenza A virus (strain A/Swine/Netherlands/12/1985 H1N1)
HEMA_I88A6
Influenza A virus (strain A/Swine/Indiana/1726/1988 H1N1)
HEMA_I96A2
Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
HEMA_I96A3
Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

29 entries

Matrix protein 1 (M1)

Select_allDeselect_all
M1_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
M1_I00A1
Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
M1_I06A0
Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
M1_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
M1_I30A0
Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)
M1_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
M1_I35A3
Influenza A virus (strain A/USA:Phila/1935 H1N1)
M1_I36A0
Influenza A virus (strain A/Henry/1936 H1N1)
M1_I37A0
Influenza A virus (strain A/Swine/29/1937 H1N1)
M1_I40A0
Influenza A virus (strain A/Hickox/1940 H1N1)
M1_I43A0
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
M1_I45A0
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
M1_I50A0
Influenza A virus (strain A/Fort Warren/1/1950 H1N1)
M1_I51A0
Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
M1_I54A1
Influenza A virus (strain A/Swine/May/1954 H1N1)
M1_I54A2
Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
M1_I61A1
Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
M1_I67A2
Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)
M1_I77AA
Influenza A virus (strain A/Brazil/11/1978 H1N1)
M1_I77AB
Influenza A virus (strain A/USSR/90/1977 H1N1)
M1_I77AC
Influenza A virus (strain A/Swine/Tennessee/24/1977 H1N1)
M1_I80AA
Influenza A virus (strain A/India/6263/1980 H1N1)
M1_I81A4
Influenza A virus (strain A/Swine/Ontario/2/1981 H1N1)
M1_I83A1
Influenza A virus (strain A/Chile/1/1983 H1N1)
M1_I85A4
Influenza A virus (strain A/Swine/Netherlands/12/1985 H1N1)
M1_I88A5
Influenza A virus (strain A/Swine/Iowa/17672/1988 H1N1)
M1_I88A7
Influenza A virus (strain A/Wisconsin/3523/1988 H1N1)
M1_I96A2
Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
M1_I96A3
Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

28 entries

Matrix protein 2 (Proton channel protein M2)

Select_allDeselect_all
M2_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
M2_I06A0
Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
M2_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
M2_I30A0
Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)
M2_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
M2_I35A3
Influenza A virus (strain A/USA:Phila/1935 H1N1)
M2_I36A0
Influenza A virus (strain A/Henry/1936 H1N1)
M2_I37A0
Influenza A virus (strain A/Swine/29/1937 H1N1)
M2_I40A0
Influenza A virus (strain A/Hickox/1940 H1N1)
M2_I43A0
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
M2_I45A0
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
M2_I50A0
Influenza A virus (strain A/Fort Warren/1/1950 H1N1)
M2_I51A0
Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
M2_I54A1
Influenza A virus (strain A/Swine/May/1954 H1N1)
M2_I54A2
Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
M2_I61A1
Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
M2_I67A2
Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)
M2_I77AA
Influenza A virus (strain A/Brazil/11/1978 H1N1)
M2_I77AB
Influenza A virus (strain A/USSR/90/1977 H1N1)
M2_I77AC
Influenza A virus (strain A/Swine/Tennessee/24/1977 H1N1)
M2_I80AA
Influenza A virus (strain A/India/6263/1980 H1N1)
M2_I81A4
Influenza A virus (strain A/Swine/Ontario/2/1981 H1N1)
M2_I83A1
Influenza A virus (strain A/Chile/1/1983 H1N1)
M2_I85A4
Influenza A virus (strain A/Swine/Netherlands/12/1985 H1N1)
M2_I88A5
Influenza A virus (strain A/Swine/Iowa/17672/1988 H1N1)
M2_I88A7
Influenza A virus (strain A/Wisconsin/3523/1988 H1N1)
M2_I96A2
Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
M2_I96A3
Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

51 entries

Nucleoprotein (Nucleocapsid protein) (Protein N)

Select_allDeselect_all
NCAP_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
NCAP_I00A1
Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
NCAP_I06A0
Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
NCAP_I07A0
Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)
NCAP_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
NCAP_I30A0
Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)
NCAP_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
NCAP_I35A1
Influenza A virus (strain A/Swine/Cambridge/1/1935 H1N1)
NCAP_I35A2
Influenza A virus (strain A/Swine/Ohio/23/1935 H1N1)
NCAP_I35A3
Influenza A virus (strain A/USA:Phila/1935 H1N1)
NCAP_I36A0
Influenza A virus (strain A/Henry/1936 H1N1)
NCAP_I37A0
Influenza A virus (strain A/Swine/29/1937 H1N1)
NCAP_I40A0
Influenza A virus (strain A/Hickox/1940 H1N1)
NCAP_I42A0
Influenza A virus (strain A/Swine/Jamesburg/1942 H1N1)
NCAP_I43A0
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
NCAP_I45A0
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
NCAP_I46A1
Influenza A virus (strain A/Swine/Iowa/1946 H1N1)
NCAP_I47A0
Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)
NCAP_I49A2
Influenza A virus (strain A/Swine/41/1949 H1N1)
NCAP_I50A0
Influenza A virus (strain A/Fort Warren/1/1950 H1N1)
NCAP_I51A0
Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
NCAP_I54A0
Influenza A virus (strain A/Leningrad/1/1954 H1N1)
NCAP_I54A1
Influenza A virus (strain A/Swine/May/1954 H1N1)
NCAP_I54A2
Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
NCAP_I55A0
Influenza A virus (strain A/England/19/1955 H1N1)
NCAP_I57A7
Influenza A virus (strain A/Swine/Wisconsin/1/1957 H1N1)
NCAP_I61A1
Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
NCAP_I67A2
Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)
NCAP_I76A7
Influenza A virus (strain A/New Jersey/8/1976 H1N1)
NCAP_I76AF
Influenza A virus (strain A/Swine/Iowa/1976/1931 H1N1)
NCAP_I76AG
Influenza A virus (strain A/Swine/Italy/437/1976 H1N1)
NCAP_I77A3
Influenza A virus (strain A/Duck/Bavaria/2/1977 H1N1)
NCAP_I77AA
Influenza A virus (strain A/Brazil/11/1978 H1N1)
NCAP_I77AB
Influenza A virus (strain A/USSR/90/1977 H1N1)
NCAP_I77AC
Influenza A virus (strain A/Swine/Tennessee/24/1977 H1N1)
NCAP_I78A6
Influenza A virus (strain A/California/10/1978 H1N1)
NCAP_I79A4
Influenza A virus (strain A/Kiev/59/1979 H1N1)
NCAP_I79A5
Influenza A virus (strain A/Swine/Italy/2/1979 H1N1)
NCAP_I80A1
Influenza A virus (strain A/Duck/Australia/749/1980 H1N1)
NCAP_I80AA
Influenza A virus (strain A/India/6263/1980 H1N1)
NCAP_I81A1
Influenza A virus (strain A/Swine/Italy/141/1981 H1N1)
NCAP_I81A3
Influenza A virus (strain A/Turkey/Minnesota/1661/1981 H1N1)
NCAP_I81A4
Influenza A virus (strain A/Swine/Ontario/2/1981 H1N1)
NCAP_I83A1
Influenza A virus (strain A/Chile/1/1983 H1N1)
NCAP_I83A2
Influenza A virus (strain A/Ohio/4/1983 H1N1)
NCAP_I85A4
Influenza A virus (strain A/Swine/Netherlands/12/1985 H1N1)
NCAP_I88A5
Influenza A virus (strain A/Swine/Iowa/17672/1988 H1N1)
NCAP_I88A7
Influenza A virus (strain A/Wisconsin/3523/1988 H1N1)
NCAP_I89A6
Influenza A virus (strain A/Swine/Italy/839/1989 H1N1)
NCAP_I96A2
Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
NCAP_I96A3
Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

25 entries

Nuclear export protein (NEP) (Non-structural protein 2) (NS2)

Select_allDeselect_all
NEP_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
NEP_I00A1
Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
NEP_I06A0
Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
NEP_I07A0
Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)
NEP_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
NEP_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
NEP_I35A3
Influenza A virus (strain A/USA:Phila/1935 H1N1)
NEP_I36A0
Influenza A virus (strain A/Henry/1936 H1N1)
NEP_I40A0
Influenza A virus (strain A/Hickox/1940 H1N1)
NEP_I43A0
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
NEP_I45A0
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
NEP_I47A0
Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)
NEP_I50A0
Influenza A virus (strain A/Fort Warren/1/1950 H1N1)
NEP_I51A0
Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
NEP_I54A0
Influenza A virus (strain A/Leningrad/1/1954 H1N1)
NEP_I54A2
Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
NEP_I61A1
Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
NEP_I67A2
Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)
NEP_I77AA
Influenza A virus (strain A/Brazil/11/1978 H1N1)
NEP_I77AB
Influenza A virus (strain A/USSR/90/1977 H1N1)
NEP_I80AA
Influenza A virus (strain A/India/6263/1980 H1N1)
NEP_I82A8
Influenza A virus (strain A/Turkey/Bethlehem-Glilit/1492-B/1982 H1N1)
NEP_I83A1
Influenza A virus (strain A/Chile/1/1983 H1N1)
NEP_I96A2
Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
NEP_I96A3
Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

26 entries

Neuraminidase (EC 3.2.1.18)

Select_allDeselect_all
NRAM_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
NRAM_I00A1
Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
NRAM_I06A0
Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
NRAM_I07A0
Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)
NRAM_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
NRAM_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
NRAM_I35A3
Influenza A virus (strain A/USA:Phila/1935 H1N1)
NRAM_I36A0
Influenza A virus (strain A/Henry/1936 H1N1)
NRAM_I40A0
Influenza A virus (strain A/Hickox/1940 H1N1)
NRAM_I43A0
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
NRAM_I45A0
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
NRAM_I47A0
Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)
NRAM_I51A0
Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
NRAM_I54A0
Influenza A virus (strain A/Leningrad/1/1954 H1N1)
NRAM_I54A2
Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
NRAM_I61A1
Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
NRAM_I67A2
Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)
NRAM_I76A7
Influenza A virus (strain A/New Jersey/8/1976 H1N1)
NRAM_I76AI
Influenza A virus (strain A/Swine/New Jersey/11/1976 H1N1)
NRAM_I77AA
Influenza A virus (strain A/Brazil/11/1978 H1N1)
NRAM_I77AB
Influenza A virus (strain A/USSR/90/1977 H1N1)
NRAM_I79A4
Influenza A virus (strain A/Kiev/59/1979 H1N1)
NRAM_I80AA
Influenza A virus (strain A/India/6263/1980 H1N1)
NRAM_I83A1
Influenza A virus (strain A/Chile/1/1983 H1N1)
NRAM_I96A2
Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
NRAM_I96A3
Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

25 entries

Non-structural protein 1 (NS1) (NS1A)

Select_allDeselect_all
NS1_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
NS1_I00A1
Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
NS1_I06A0
Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
NS1_I07A0
Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)
NS1_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
NS1_I30A0
Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)
NS1_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
NS1_I35A3
Influenza A virus (strain A/USA:Phila/1935 H1N1)
NS1_I36A0
Influenza A virus (strain A/Henry/1936 H1N1)
NS1_I40A0
Influenza A virus (strain A/Hickox/1940 H1N1)
NS1_I43A0
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
NS1_I45A0
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
NS1_I47A0
Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)
NS1_I50A0
Influenza A virus (strain A/Fort Warren/1/1950 H1N1)
NS1_I51A0
Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
NS1_I54A0
Influenza A virus (strain A/Leningrad/1/1954 H1N1)
NS1_I54A2
Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
NS1_I61A1
Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
NS1_I77AA
Influenza A virus (strain A/Brazil/11/1978 H1N1)
NS1_I77AB
Influenza A virus (strain A/USSR/90/1977 H1N1)
NS1_I80AA
Influenza A virus (strain A/India/6263/1980 H1N1)
NS1_I82A8
Influenza A virus (strain A/Turkey/Bethlehem-Glilit/1492-B/1982 H1N1)
NS1_I83A1
Influenza A virus (strain A/Chile/1/1983 H1N1)
NS1_I96A2
Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
NS1_I96A3
Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

24 entries

Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)

Select_allDeselect_all
PA_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
PA_I00A1
Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
PA_I06A0
Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
PA_I07A0
Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)
PA_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
PA_I30A0
Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)
PA_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
PA_I35A3
Influenza A virus (strain A/USA:Phila/1935 H1N1)
PA_I36A0
Influenza A virus (strain A/Henry/1936 H1N1)
PA_I40A0
Influenza A virus (strain A/Hickox/1940 H1N1)
PA_I43A0
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
PA_I45A0
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
PA_I47A0
Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)
PA_I51A0
Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
PA_I54A2
Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
PA_I61A1
Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
PA_I67A2
Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)
PA_I77AA
Influenza A virus (strain A/Brazil/11/1978 H1N1)
PA_I77AB
Influenza A virus (strain A/USSR/90/1977 H1N1)
PA_I77AD
Influenza A virus (strain A/Swine/Tennessee/26/1977 H1N1)
PA_I80AA
Influenza A virus (strain A/India/6263/1980 H1N1)
PA_I83A1
Influenza A virus (strain A/Chile/1/1983 H1N1)
PA_I96A2
Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
PA_I96A3
Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

24 entries

Protein PA-X

Select_allDeselect_all
PAX_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
PAX_I00A1
Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
PAX_I06A0
Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
PAX_I07A0
Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)
PAX_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
PAX_I30A0
Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)
PAX_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
PAX_I35A3
Influenza A virus (strain A/USA:Phila/1935 H1N1)
PAX_I36A0
Influenza A virus (strain A/Henry/1936 H1N1)
PAX_I40A0
Influenza A virus (strain A/Hickox/1940 H1N1)
PAX_I43A0
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
PAX_I45A0
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
PAX_I47A0
Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)
PAX_I51A0
Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
PAX_I54A2
Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
PAX_I61A1
Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
PAX_I67A2
Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)
PAX_I77AA
Influenza A virus (strain A/Brazil/11/1978 H1N1)
PAX_I77AB
Influenza A virus (strain A/USSR/90/1977 H1N1)
PAX_I77AD
Influenza A virus (strain A/Swine/Tennessee/26/1977 H1N1)
PAX_I80AA
Influenza A virus (strain A/India/6263/1980 H1N1)
PAX_I83A1
Influenza A virus (strain A/Chile/1/1983 H1N1)
PAX_I96A2
Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
PAX_I96A3
Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

21 entries

Protein PB1-F2

Select_allDeselect_all
PB1F2_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
PB1F2_I00A1
Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
PB1F2_I06A0
Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
PB1F2_I07A0
Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)
PB1F2_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
PB1F2_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
PB1F2_I35A3
Influenza A virus (strain A/USA:Phila/1935 H1N1)
PB1F2_I36A0
Influenza A virus (strain A/Henry/1936 H1N1)
PB1F2_I40A0
Influenza A virus (strain A/Hickox/1940 H1N1)
PB1F2_I43A0
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
PB1F2_I45A0
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
PB1F2_I51A0
Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
PB1F2_I54A2
Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
PB1F2_I61A1
Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
PB1F2_I67A2
Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)

Putative protein PB1-F2

PB1F2_I77AA
Influenza A virus (strain A/Brazil/11/1978 H1N1)
PB1F2_I77AB
Influenza A virus (strain A/USSR/90/1977 H1N1)
PB1F2_I80AA
Influenza A virus (strain A/India/6263/1980 H1N1)
PB1F2_I83A1
Influenza A virus (strain A/Chile/1/1983 H1N1)
PB1F2_I96A2
Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
PB1F2_I96A3
Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

25 entries

Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

Select_allDeselect_all
PB2_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
PB2_I00A1
Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
PB2_I06A0
Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
PB2_I07A0
Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)
PB2_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
PB2_I30A0
Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)
PB2_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
PB2_I35A3
Influenza A virus (strain A/USA:Phila/1935 H1N1)
PB2_I36A0
Influenza A virus (strain A/Henry/1936 H1N1)
PB2_I40A0
Influenza A virus (strain A/Hickox/1940 H1N1)
PB2_I43A0
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
PB2_I45A0
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
PB2_I47A0
Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)
PB2_I51A0
Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
PB2_I54A2
Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
PB2_I61A1
Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
PB2_I67A2
Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)
PB2_I77AA
Influenza A virus (strain A/Brazil/11/1978 H1N1)
PB2_I77AB
Influenza A virus (strain A/USSR/90/1977 H1N1)
PB2_I77AC
Influenza A virus (strain A/Swine/Tennessee/24/1977 H1N1)
PB2_I79A4
Influenza A virus (strain A/Kiev/59/1979 H1N1)
PB2_I80AA
Influenza A virus (strain A/India/6263/1980 H1N1)
PB2_I83A1
Influenza A virus (strain A/Chile/1/1983 H1N1)
PB2_I96A2
Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
PB2_I96A3
Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

3 entries

PB2-S1

Select_allDeselect_all
PB2S1_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
PB2S1_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
PB2S1_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))

27 entries

RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) (RNA-directed RNA polymerase subunit P1)

Select_allDeselect_all
RDRP_I34A1
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
RDRP_I00A1
Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
RDRP_I06A0
Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
RDRP_I07A0
Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)
RDRP_I18A0
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))
RDRP_I33A0
Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
RDRP_I35A3
Influenza A virus (strain A/USA:Phila/1935 H1N1)
RDRP_I36A0
Influenza A virus (strain A/Henry/1936 H1N1)
RDRP_I40A0
Influenza A virus (strain A/Hickox/1940 H1N1)
RDRP_I43A0
Influenza A virus (strain A/USA:Iowa/1943 H1N1)
RDRP_I45A0
Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
RDRP_I47A0
Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)
RDRP_I51A0
Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
RDRP_I54A2
Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
RDRP_I56A0
Influenza A virus (strain A/Beijing/11/1956 H1N1)
RDRP_I61A1
Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
RDRP_I67A2
Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)
RDRP_I77AA
Influenza A virus (strain A/Brazil/11/1978 H1N1)
RDRP_I77AB
Influenza A virus (strain A/USSR/90/1977 H1N1)
RDRP_I77AD
Influenza A virus (strain A/Swine/Tennessee/26/1977 H1N1)
RDRP_I79A4
Influenza A virus (strain A/Kiev/59/1979 H1N1)
RDRP_I80AA
Influenza A virus (strain A/India/6263/1980 H1N1)
RDRP_I81A4
Influenza A virus (strain A/Swine/Ontario/2/1981 H1N1)
RDRP_I83A1
Influenza A virus (strain A/Chile/1/1983 H1N1)
RDRP_I88A7
Influenza A virus (strain A/Wisconsin/3523/1988 H1N1)
RDRP_I96A2
Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
RDRP_I96A3
Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)