H1N1 subtype

VIRION

Molecular biology

Enveloped. Usually rounded but can be filamentous. The virions are 80-120 nm in diameter.

GENOME

Segmented ssRNA(-) linear genome, encapsidated by nucleoprotein (NP). Contains 8 segments coding for 12-14 proteins depending on strains. Segments size range from 890 to 2,341nt. Genome total size is 13.5Kb

GENE EXPRESSION

Viral RNA polymerase (PB1, PB2 and PA) transcribes one mRNA from each genome segment. Transcription is primed by cap cleaved from cellular mRNAS by Cap snatching. mRNA are polyadenylated by the viral polymerase stuttering on a poly U track. MP and NS mRNA can be alternately spliced, giving rise to mRNA coding for M2 and NEP proteins. Some strains can express M42 from the M segment . PB1 mRNA encode three proteins by leaky scanning: PB1, N40 and PB1-F2 . Pa-X protein is translated by ribosomal frameshift on the PA gene. Leaky scanning may produces N-truncated PA proteins, namely PA-N155 and PA-N182 . PB2-S1 would be an alternative splicing from PB2 gene (unpublished 1/1/15).

REPLICATION

NUCLEUS

  1. Virus attaches to sialic acid receptor though HA protein and is endocytosed by clathrins in the host cell.
  2. endosome acidification induces fusion of virus membrane with the vesicle membrane; encapsidated RNA segments migrate to the nucleus.
  3. Transcription of genomic segments by the viral polymerase produces mRNAs that are capped and polyadenylated by the viral polymerase.
  4. Replication of genomic segments.
  5. High level of M1 protein induces genomes segments export from nucleus by NEP protein.
  6. Virus assembly and budding occurs at the plasma membrane.

Host-virus interaction

Innate immune response inhibition

Influenza A virus inhibits the cascade leading to production of interferon-beta by targeting different cellular proteins. NS1 inhibits host RIG-I activation upon recognition of viral RNA, and subsequent induction of IFN-beta expression.

PB1-F2 inhibits host MAVS activation.

Host protein shutoff

NS1 induces host gene expression shutoff by inducing host mRNA suppression through polyadenlyation inhibition. The viral mRNA are not affected because their polyA tail is generated by polymerase stuttering.

Matching UniProtKB/Swiss-Prot entries

335 entries grouped by strain (browse by keywords)

All proteins are shown (view only 234 complete proteome entries)

12 entries

Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain

Select_allDeselect_all
HEMA_I34A1 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I34A1 Nucleoprotein (Nucleocapsid protein) (Protein N)
NEP_I34A1 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
M2_I34A1 Matrix protein 2 (Proton channel protein M2)
M1_I34A1 Matrix protein 1 (M1)
NS1_I34A1 Non-structural protein 1 (NS1) (NS1A)
NRAM_I34A1 Neuraminidase (EC 3.2.1.18)
PA_I34A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PAX_I34A1 Protein PA-X
PB1F2_I34A1 Protein PB1-F2
PB2_I34A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
RDRP_I34A1 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/Brazil/11/1978 H1N1)

Select_allDeselect_all
HEMA_I77AA Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I77AA Nucleoprotein (Nucleocapsid protein) (Protein N)
NEP_I77AA Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
M2_I77AA Matrix protein 2
M1_I77AA Matrix protein 1 (M1)
NS1_I77AA Non-structural protein 1 (NS1) (NS1A)
NRAM_I77AA Neuraminidase (EC 3.2.1.18)
PAX_I77AA Protein PA-X
PB2_I77AA Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I77AA Protein PB1-F2
PA_I77AA Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
RDRP_I77AA RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus (strain A/South Carolina/1/1918 H1N1))

Select_allDeselect_all
HEMA_I18A0 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I18A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
NEP_I18A0 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
M1_I18A0 Matrix protein 1 (M1)
M2_I18A0 Matrix protein 2 (Proton channel protein M2)
NS1_I18A0 Non-structural protein 1 (NS1) (NS1A)
PB2_I18A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
NRAM_I18A0 Neuraminidase (EC 3.2.1.18)
PAX_I18A0 Protein PA-X
PA_I18A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB1F2_I18A0 Protein PB1-F2
RDRP_I18A0 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/Chile/1/1983 H1N1)

Select_allDeselect_all
HEMA_I83A1 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NEP_I83A1 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NCAP_I83A1 Nucleoprotein (Nucleocapsid protein) (Protein N)
M2_I83A1 Matrix protein 2
M1_I83A1 Matrix protein 1 (M1)
NS1_I83A1 Non-structural protein 1 (NS1) (NS1A)
NRAM_I83A1 Neuraminidase (EC 3.2.1.18)
PB2_I83A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I83A1 Protein PB1-F2
PAX_I83A1 Protein PA-X
PA_I83A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
RDRP_I83A1 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

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HEMA_I96A3 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I96A3 Nucleoprotein (Nucleocapsid protein) (Protein N)
NEP_I96A3 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
M2_I96A3 Matrix protein 2
M1_I96A3 Matrix protein 1 (M1)
NRAM_I96A3 Neuraminidase (EC 3.2.1.18)
NS1_I96A3 Non-structural protein 1 (NS1) (NS1A)
PB2_I96A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I96A3 Protein PB1-F2
PAX_I96A3 Protein PA-X
PA_I96A3 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
RDRP_I96A3 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/Henry/1936 H1N1)

Select_allDeselect_all
HEMA_I36A0 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I36A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
M1_I36A0 Matrix protein 1 (M1)
M2_I36A0 Matrix protein 2
NS1_I36A0 Non-structural protein 1 (NS1) (NS1A)
NRAM_I36A0 Neuraminidase (EC 3.2.1.18)
NEP_I36A0 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
PAX_I36A0 Protein PA-X
PB2_I36A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I36A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB1F2_I36A0 Protein PB1-F2
RDRP_I36A0 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/Hickox/1940 H1N1)

Select_allDeselect_all
HEMA_I40A0 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I40A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
NEP_I40A0 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NRAM_I40A0 Neuraminidase (EC 3.2.1.18)
M1_I40A0 Matrix protein 1 (M1)
M2_I40A0 Matrix protein 2
PA_I40A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
NS1_I40A0 Non-structural protein 1 (NS1) (NS1A)
PB1F2_I40A0 Protein PB1-F2
PAX_I40A0 Protein PA-X
PB2_I40A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
RDRP_I40A0 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/India/6263/1980 H1N1)

Select_allDeselect_all
HEMA_I80AA Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I80AA Nucleoprotein (Nucleocapsid protein) (Protein N)
M1_I80AA Matrix protein 1 (M1)
M2_I80AA Matrix protein 2
NS1_I80AA Non-structural protein 1 (NS1) (NS1A)
NEP_I80AA Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
PAX_I80AA Protein PA-X
NRAM_I80AA Neuraminidase (EC 3.2.1.18)
PB1F2_I80AA Protein PB1-F2
PA_I80AA Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I80AA Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
RDRP_I80AA RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)

Select_allDeselect_all
HEMA_I54A2 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NEP_I54A2 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NCAP_I54A2 Nucleoprotein (Nucleocapsid protein) (Protein N)
M1_I54A2 Matrix protein 1 (M1)
M2_I54A2 Matrix protein 2
NS1_I54A2 Non-structural protein 1 (NS1) (NS1A)
PA_I54A2 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB1F2_I54A2 Protein PB1-F2
NRAM_I54A2 Neuraminidase (EC 3.2.1.18)
PAX_I54A2 Protein PA-X
PB2_I54A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
RDRP_I54A2 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)

Select_allDeselect_all
HEMA_I06A0 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I06A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
NEP_I06A0 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NRAM_I06A0 Neuraminidase (EC 3.2.1.18)
M2_I06A0 Matrix protein 2
M1_I06A0 Matrix protein 1 (M1)
PAX_I06A0 Protein PA-X
PA_I06A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
NS1_I06A0 Non-structural protein 1 (NS1) (NS1A)
PB1F2_I06A0 Protein PB1-F2
PB2_I06A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
RDRP_I06A0 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)

Select_allDeselect_all
HEMA_I61A1 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I61A1 Nucleoprotein (Nucleocapsid protein) (Protein N)
NEP_I61A1 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NRAM_I61A1 Neuraminidase (EC 3.2.1.18)
M1_I61A1 Matrix protein 1 (M1)
M2_I61A1 Matrix protein 2 (Proton channel protein M2)
NS1_I61A1 Non-structural protein 1 (NS1) (NS1A)
PAX_I61A1 Protein PA-X
PB1F2_I61A1 Protein PB1-F2
PB2_I61A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I61A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
RDRP_I61A1 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/USA:Albany/12/1951 H1N1)

Select_allDeselect_all
HEMA_I51A0 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NEP_I51A0 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NCAP_I51A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
M1_I51A0 Matrix protein 1 (M1)
M2_I51A0 Matrix protein 2
NS1_I51A0 Non-structural protein 1 (NS1) (NS1A)
NRAM_I51A0 Neuraminidase (EC 3.2.1.18)
PAX_I51A0 Protein PA-X
PA_I51A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I51A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I51A0 Protein PB1-F2
RDRP_I51A0 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)

Select_allDeselect_all
HEMA_I45A0 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I45A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
NEP_I45A0 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NRAM_I45A0 Neuraminidase (EC 3.2.1.18)
M2_I45A0 Matrix protein 2
M1_I45A0 Matrix protein 1 (M1)
NS1_I45A0 Non-structural protein 1 (NS1) (NS1A)
PB2_I45A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PAX_I45A0 Protein PA-X
PB1F2_I45A0 Protein PB1-F2
PA_I45A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
RDRP_I45A0 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/USA:Iowa/1943 H1N1)

Select_allDeselect_all
HEMA_I43A0 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NEP_I43A0 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NCAP_I43A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
M2_I43A0 Matrix protein 2
M1_I43A0 Matrix protein 1 (M1)
PA_I43A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB1F2_I43A0 Protein PB1-F2
NS1_I43A0 Non-structural protein 1 (NS1) (NS1A)
NRAM_I43A0 Neuraminidase (EC 3.2.1.18)
PAX_I43A0 Protein PA-X
PB2_I43A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
RDRP_I43A0 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)

Select_allDeselect_all
HEMA_I96A2 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NEP_I96A2 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NCAP_I96A2 Nucleoprotein (Nucleocapsid protein) (Protein N)
M1_I96A2 Matrix protein 1 (M1)
M2_I96A2 Matrix protein 2
NS1_I96A2 Non-structural protein 1 (NS1) (NS1A)
PAX_I96A2 Protein PA-X
NRAM_I96A2 Neuraminidase (EC 3.2.1.18)
PA_I96A2 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I96A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I96A2 Protein PB1-F2
RDRP_I96A2 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/USA:Phila/1935 H1N1)

Select_allDeselect_all
HEMA_I35A3 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NEP_I35A3 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NCAP_I35A3 Nucleoprotein (Nucleocapsid protein) (Protein N)
M2_I35A3 Matrix protein 2
M1_I35A3 Matrix protein 1 (M1)
NRAM_I35A3 Neuraminidase (EC 3.2.1.18)
NS1_I35A3 Non-structural protein 1 (NS1) (NS1A)
PB1F2_I35A3 Protein PB1-F2
PAX_I35A3 Protein PA-X
PB2_I35A3 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PA_I35A3 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
RDRP_I35A3 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/USSR/90/1977 H1N1)

Select_allDeselect_all
HEMA_I77AB Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I77AB Nucleoprotein (Nucleocapsid protein) (Protein N)
NEP_I77AB Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
M2_I77AB Matrix protein 2 (Proton channel protein M2)
M1_I77AB Matrix protein 1 (M1)
NS1_I77AB Non-structural protein 1 (NS1) (NS1A)
NRAM_I77AB Neuraminidase (EC 3.2.1.18)
PAX_I77AB Protein PA-X
PA_I77AB Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I77AB Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I77AB Protein PB1-F2
RDRP_I77AB RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

12 entries

Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))

Select_allDeselect_all
HEMA_I33A0 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NEP_I33A0 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NCAP_I33A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
M1_I33A0 Matrix protein 1 (M1)
M2_I33A0 Matrix protein 2 (Proton channel protein M2)
NS1_I33A0 Non-structural protein 1 (NS1) (NS1A)
PB1F2_I33A0 Protein PB1-F2
PA_I33A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
NRAM_I33A0 Neuraminidase (EC 3.2.1.18)
PAX_I33A0 Protein PA-X
PB2_I33A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
RDRP_I33A0 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

11 entries

Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)

Select_allDeselect_all
HEMA_I00A1 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NEP_I00A1 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NCAP_I00A1 Nucleoprotein (Nucleocapsid protein) (Protein N)
M1_I00A1 Matrix protein 1 (M1)
NS1_I00A1 Non-structural protein 1 (NS1) (NS1A)
NRAM_I00A1 Neuraminidase (EC 3.2.1.18)
PAX_I00A1 Protein PA-X
PA_I00A1 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB1F2_I00A1 Protein PB1-F2
PB2_I00A1 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
RDRP_I00A1 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

11 entries

Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)

Select_allDeselect_all
HEMA_I67A2 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NEP_I67A2 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NCAP_I67A2 Nucleoprotein (Nucleocapsid protein) (Protein N)
NRAM_I67A2 Neuraminidase (EC 3.2.1.18)
M1_I67A2 Matrix protein 1 (M1)
M2_I67A2 Matrix protein 2
PB1F2_I67A2 Protein PB1-F2
PA_I67A2 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I67A2 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PAX_I67A2 Protein PA-X
RDRP_I67A2 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

10 entries

Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)

Select_allDeselect_all
HEMA_I07A0 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NEP_I07A0 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NCAP_I07A0 Nucleocapsid protein
NS1_I07A0 Non-structural protein 1 (NS1) (NS1A)
NRAM_I07A0 Neuraminidase (EC 3.2.1.18)
PA_I07A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I07A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
PB1F2_I07A0 Protein PB1-F2
PAX_I07A0 Protein PA-X
RDRP_I07A0 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

8 entries

Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)

Select_allDeselect_all
NCAP_I47A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
NEP_I47A0 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
PAX_I47A0 Protein PA-X
NRAM_I47A0 Neuraminidase (EC 3.2.1.18)
NS1_I47A0 Non-structural protein 1 (NS1) (NS1A)
PA_I47A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I47A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
RDRP_I47A0 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

8 entries

Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)

Select_allDeselect_all
HEMA_I30A0 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I30A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
M2_I30A0 Matrix protein 2 (Proton channel protein M2)
M1_I30A0 Matrix protein 1 (M1)
NS1_I30A0 Non-structural protein 1 (NS1) (NS1A)
PAX_I30A0 Protein PA-X
PA_I30A0 Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PB2_I30A0 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

5 entries

Influenza A virus (strain A/Fort Warren/1/1950 H1N1)

Select_allDeselect_all
NCAP_I50A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
NEP_I50A0 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
M2_I50A0 Matrix protein 2 (Proton channel protein M2)
M1_I50A0 Matrix protein 1 (M1)
NS1_I50A0 Non-structural protein 1 (NS1) (NS1A)

5 entries

Influenza A virus (strain A/Kiev/59/1979 H1N1)

Select_allDeselect_all
HEMA_I79A4 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I79A4 Nucleoprotein (Nucleocapsid protein) (Protein N)
NRAM_I79A4 Neuraminidase (EC 3.2.1.18)
PB2_I79A4 Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)
RDRP_I79A4 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

5 entries

Influenza A virus (strain A/Leningrad/1/1954 H1N1)

Select_allDeselect_all
HEMA_I54A0 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I54A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
NEP_I54A0 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NRAM_I54A0 Neuraminidase (EC 3.2.1.18)
NS1_I54A0 Non-structural protein 1 (NS1) (NS1A)

4 entries

Influenza A virus (strain A/Swine/Netherlands/12/1985 H1N1)

Select_allDeselect_all
HEMA_I85A4 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I85A4 Nucleoprotein (Nucleocapsid protein) (Protein N)
M2_I85A4 Matrix protein 2 (Proton channel protein M2)
M1_I85A4 Matrix protein 1 (M1)

4 entries

Influenza A virus (strain A/Swine/Ontario/2/1981 H1N1)

Select_allDeselect_all
NCAP_I81A4 Nucleoprotein (Nucleocapsid protein) (Protein N)
M1_I81A4 Matrix protein 1 (M1)
M2_I81A4 Matrix protein 2 (Proton channel protein M2)
RDRP_I81A4 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

4 entries

Influenza A virus (strain A/Swine/Tennessee/24/1977 H1N1)

Select_allDeselect_all
NCAP_I77AC Nucleoprotein (Nucleocapsid protein) (Protein N)
M1_I77AC Matrix protein 1 (M1)
M2_I77AC Matrix protein 2 (Proton channel protein M2)
PB2_I77AC Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

4 entries

Influenza A virus (strain A/Wisconsin/3523/1988 H1N1)

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NCAP_I88A7 Nucleoprotein (Nucleocapsid protein) (Protein N)
M1_I88A7 Matrix protein 1 (M1)
M2_I88A7 Matrix protein 2 (Proton channel protein M2)
RDRP_I88A7 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

3 entries

Influenza A virus (strain A/Swine/29/1937 H1N1)

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NCAP_I37A0 Nucleoprotein (Nucleocapsid protein) (Protein N)
M2_I37A0 Matrix protein 2 (Proton channel protein M2)
M1_I37A0 Matrix protein 1 (M1)

3 entries

Influenza A virus (strain A/Swine/Iowa/17672/1988 H1N1)

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NCAP_I88A5 Nucleoprotein (Nucleocapsid protein) (Protein N)
M2_I88A5 Matrix protein 2 (Proton channel protein M2)
M1_I88A5 Matrix protein 1 (M1)

3 entries

Influenza A virus (strain A/Swine/May/1954 H1N1)

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NCAP_I54A1 Nucleoprotein (Nucleocapsid protein) (Protein N)
M2_I54A1 Matrix protein 2 (Proton channel protein M2)
M1_I54A1 Matrix protein 1 (M1)

3 entries

Influenza A virus (strain A/Swine/Tennessee/26/1977 H1N1)

Select_allDeselect_all
PA_I77AD Polymerase acidic protein (EC 3.1.-.-) (RNA-directed RNA polymerase subunit P2)
PAX_I77AD Protein PA-X
RDRP_I77AD RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

2 entries

Influenza A virus (strain A/Duck/Australia/749/1980 H1N1)

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HEMA_I80A1 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I80A1 Nucleoprotein (Nucleocapsid protein) (Protein N)

2 entries

Influenza A virus (strain A/New Jersey/8/1976 H1N1)

Select_allDeselect_all
NCAP_I76A7 Nucleoprotein (Nucleocapsid protein) (Protein N)
NRAM_I76A7 Neuraminidase (EC 3.2.1.18)

2 entries

Influenza A virus (strain A/Swine/New Jersey/11/1976 H1N1)

Select_allDeselect_all
HEMA_I76AI Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NRAM_I76AI Neuraminidase (EC 3.2.1.18)

2 entries

Influenza A virus (strain A/Turkey/Bethlehem-Glilit/1492-B/1982 H1N1)

Select_allDeselect_all
NEP_I82A8 Nuclear export protein (NEP) (Non-structural protein 2) (NS2)
NS1_I82A8 Non-structural protein 1 (NS1) (NS1A)

2 entries

Influenza A virus (strain A/Turkey/Minnesota/1661/1981 H1N1)

Select_allDeselect_all
HEMA_I81A3 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]
NCAP_I81A3 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Beijing/11/1956 H1N1)

RDRP_I56A0 RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) ...

1 entry

Influenza A virus (strain A/California/10/1978 H1N1)

NCAP_I78A6 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Duck/Alberta/35/1976 H1N1)

HEMA_I76A4 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]

1 entry

Influenza A virus (strain A/Duck/Bavaria/2/1977 H1N1)

NCAP_I77A3 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/England/19/1955 H1N1)

NCAP_I55A0 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Ohio/4/1983 H1N1)

NCAP_I83A2 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Swine/41/1949 H1N1)

NCAP_I49A2 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Swine/Cambridge/1/1935 H1N1)

NCAP_I35A1 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Swine/Indiana/1726/1988 H1N1)

HEMA_I88A6 Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]

1 entry

Influenza A virus (strain A/Swine/Iowa/1946 H1N1)

NCAP_I46A1 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Swine/Iowa/1976/1931 H1N1)

NCAP_I76AF Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Swine/Italy/141/1981 H1N1)

NCAP_I81A1 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Swine/Italy/2/1979 H1N1)

NCAP_I79A5 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Swine/Italy/437/1976 H1N1)

NCAP_I76AG Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Swine/Italy/839/1989 H1N1)

NCAP_I89A6 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Swine/Jamesburg/1942 H1N1)

NCAP_I42A0 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Swine/Ohio/23/1935 H1N1)

NCAP_I35A2 Nucleoprotein (Nucleocapsid protein) (Protein N)

1 entry

Influenza A virus (strain A/Swine/Wisconsin/1/1957 H1N1)

NCAP_I57A7 Nucleoprotein (Nucleocapsid protein) (Protein N)