Virus Family Viral protein Primary receptor(s) Entry receptor(s) entry mode
Rhesus Rotavirus Reoviridae, Rotavirus VP4 Sialic acids
JAM-A
Integrin α2 β1
Integrin α4 β1
Integrin αV β3
Clathrin/caveolin-independent endocytosis
Porcine Rotavirus Reoviridae, Rotavirus VP4 Sialic acids ? Clathrin-mediated endocytosis
Human Rotavirus strain Wa Reoviridae, Rotavirus VP4 JAM-A Integrin α2 β1 Clathrin-mediated endocytosis
Mammalian reovirus Reoviridae,
Orthoreovirus
Sigma-1 JAM-A , Carbohydrates Integrin β1
RTN4R(NgR1)
Clathrin-mediated endocytosis
Bluetongue virus Reoviridae ,
Orbivirus
Outer capsid protein VP2 Sialic acids?
Heparan sulfate
Clathrin-mediated endocytosis
VP7 Integrin? Clathrin-mediated endocytosis