Potexvirus

VIRION

Non-enveloped, flexuous, filamentous, 470-1000 nm or more long and 12-13 nm in diameter.

GENOME

Linear ssRNA(+) genome of 5.9-7 kb in size. The 5' end is capped and 3' terminus is polyadenylated. Encodes for 5 proteins.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. RNA-dependent RNA polymerase (RdRp) is translated directly from the genomic RNA. The other ORFS are transcribed presumably as monocistronic subgenomic mRNAs (sgRNAs). TGB3 is expressed by leaky scanning of the TGB2 subgenomic mRNA.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated as a monocistronic mRNA to produce the RdRp (encoded by the 5'-proximal ORF).
  4. Replication occurs in viral factories recruited by TGB1. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Internal subgenomic promoters are used to transcribe the sgRNAs. Traduction of these sgRNAs yields the capsid and movement proteins.
  7. Assembly of new virus particles.
  8. Triple gene block proteins (TGBp) allow cell-to-cell and long-distance movement.

Host-virus interaction

Suppression of RNA silencing

Potato virus X TGBp1 protein functions as a suppressor of RNA silencing inhibiting the PTGS pathway .

Matching UniProtKB/Swiss-Prot entries

71 entries grouped by protein (browse by keywords)

All proteins are shown (view only 58 complete proteome entries)

17 entries

Coat protein (Capsid protein) (CP)

Select_allDeselect_all
CAPSD_FXMV
Foxtail mosaic virus reference strain
CAPSD_NMV
Narcissus mosaic virus (NMV) reference strain
CAPSD_P1AMV
Plantago asiatica mosaic potexvirus (P1AMV) reference strain
CAPSD_PMV
Papaya mosaic potexvirus (PMV) reference strain
CAPSD_PVXX3
Potato virus X (strain X3) (PVX) reference strain
CAPSD_SMYEA
Strawberry mild yellow edge-associated virus (SMYEaV) reference strain
CAPSD_WCMVM
White clover mosaic virus (strain M) (WCMV) reference strain
CAPSD_CMVSI
Cymbidium mosaic virus (strain Singapore)
CAPSD_CYMV
Clover yellow mosaic virus (CYMV)
CAPSD_LVX
Lily virus X
CAPSD_PAMV
Potato aucuba mosaic virus (PAMV)
CAPSD_PVX
Potato virus X (PVX)
CAPSD_PVXCP
Potato virus X (strain CP) (PVX)
CAPSD_PVXHB
Potato virus X (strain HB) (PVX)
CAPSD_PVXU3
Potato virus X (strain UK3) (PVX)
CAPSD_PVXXC
Potato virus X (strain Xc) (PVX)
CAPSD_WCMVO
White clover mosaic virus (strain O) (WCMV)

11 entries

RNA replication protein (165 kDa protein) (ORF1 protein)

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RDRP_FXMV
Foxtail mosaic virus reference strain

RNA replication protein (152 kDa protein) (ORF1 protein)

RDRP_NMV
Narcissus mosaic virus (NMV) reference strain

RNA replication protein (186 kDa protein) (ORF1 protein)

RDRP_P1AMV
Plantago asiatica mosaic potexvirus (P1AMV) reference strain

RNA replication protein (156 kDa protein) (ORF1 protein)

RDRP_PMV
Papaya mosaic potexvirus (PMV) reference strain

RNA replication protein (176 kDa protein) (ORF1 protein)

RDRP_PVXX3
Potato virus X (strain X3) (PVX) reference strain
RDRP_SMYEA
Strawberry mild yellow edge-associated virus (SMYEaV) reference strain

RNA replication protein (150 kDa protein) (ORF1 protein)

RDRP_WCMVM
White clover mosaic virus (strain M) (WCMV) reference strain

RNA replication protein (147 kDa protein) (ORF1 protein)

RDRP_PVX
Potato virus X (PVX)
RDRP_PVXCP
Potato virus X (strain CP) (PVX)
RDRP_PVXHB
Potato virus X (strain HB) (PVX)
RDRP_WCMVO
White clover mosaic virus (strain O) (WCMV)

RNA replication protein (147 kDa protein) (ORF1 protein)

12 entries

Movement and silencing protein TGBp1 (25 kDa protein) (Silencing suppressor P25) (Triple gene block 1 protein) (TGBp1)

Select_allDeselect_all
TGB1_FXMV
Foxtail mosaic virus reference strain
TGB1_NMV
Narcissus mosaic virus (NMV) reference strain
TGB1_P1AMV
Plantago asiatica mosaic potexvirus (P1AMV) reference strain
TGB1_PMV
Papaya mosaic potexvirus (PMV) reference strain
TGB1_PVXX3
Potato virus X (strain X3) (PVX) reference strain
TGB1_SMYEA
Strawberry mild yellow edge-associated virus (SMYEaV) reference strain
TGB1_WCMVM
White clover mosaic virus (strain M) (WCMV) reference strain
TGB1_LVX
Lily virus X
TGB1_PVX
Potato virus X (PVX)
TGB1_PVXCP
Potato virus X (strain CP) (PVX)
TGB1_PVXHB
Potato virus X (strain HB) (PVX)
TGB1_WCMVO
White clover mosaic virus (strain O) (WCMV)

12 entries

Movement protein TGB2 (12 kDa protein) (Triple gene block 2 protein) (TGBp2)

Select_allDeselect_all
TGB2_FXMV
Foxtail mosaic virus reference strain
TGB2_NMV
Narcissus mosaic virus (NMV) reference strain

Movement protein TGB2 (14 kDa protein) (Triple gene block 2 protein) (TGBp2)

TGB2_P1AMV
Plantago asiatica mosaic potexvirus (P1AMV) reference strain
TGB2_PMV
Papaya mosaic potexvirus (PMV) reference strain
TGB2_PVXX3
Potato virus X (strain X3) (PVX) reference strain
TGB2_SMYEA
Strawberry mild yellow edge-associated virus (SMYEaV) reference strain
TGB2_WCMVM
White clover mosaic virus (strain M) (WCMV) reference strain

Movement protein TGB2 (13 kDa protein) (Triple gene block 2 protein) (TGBp2)

TGB2_LVX
Lily virus X
TGB2_PVX
Potato virus X (PVX)
TGB2_PVXCP
Potato virus X (strain CP) (PVX)
TGB2_PVXHB
Potato virus X (strain HB) (PVX)
TGB2_WCMVO
White clover mosaic virus (strain O) (WCMV)

Movement protein TGB2 (13 kDa protein) (Triple gene block 2 protein) (TGBp2)

14 entries

Movement protein TGBp3 (7 kDa protein) (Triple gene block 3 protein) (TGBp3)

Select_allDeselect_all
TGB3_FXMV
Foxtail mosaic virus reference strain
TGB3_NMV
Narcissus mosaic virus (NMV) reference strain
TGB3_P1AMV
Plantago asiatica mosaic potexvirus (P1AMV) reference strain

Movement protein TGBp3 (13 kDa protein) (Triple gene block 3 protein) (TGBp3)

TGB3_PMV
Papaya mosaic potexvirus (PMV) reference strain
TGB3_PVXX3
Potato virus X (strain X3) (PVX) reference strain
TGB3_SMYEA
Strawberry mild yellow edge-associated virus (SMYEaV) reference strain

Movement protein TGBp3 (8.1 kDa protein) (Triple gene block 3 protein) (TGBp3)

TGB3_WCMVM
White clover mosaic virus (strain M) (WCMV) reference strain
TGB3_CMVSI
Cymbidium mosaic virus (strain Singapore)

Movement protein TGBp3 (9.7 kDa protein) (Triple gene block 3 protein) (TGBp3)

TGB3_CYMV
Clover yellow mosaic virus (CYMV)
TGB3_PVX
Potato virus X (PVX)
TGB3_PVXCP
Potato virus X (strain CP) (PVX)
TGB3_PVXHB
Potato virus X (strain HB) (PVX)

Movement protein TGBp3 (9.7 kDa protein) (Triple gene block 3 protein) (TGBp3)

TGB3_PVXXC
Potato virus X (strain Xc) (PVX)
TGB3_WCMVO
White clover mosaic virus (strain O) (WCMV)

1 entry

Uncharacterized 12.4 kDa protein

Y12K_CMVSI
Cymbidium mosaic virus (strain Singapore)

1 entry

Uncharacterized 14.1 kDa protein in ORF1 coding strand

Y14K_PMV
Papaya mosaic potexvirus (PMV) reference strain

1 entry

Uncharacterized 14.7 kDa protein in coat protein coding strand

Y15K_PMV
Papaya mosaic potexvirus (PMV) reference strain

1 entry

Uncharacterized 5.8 kDa protein

Y5K_CYMV
Clover yellow mosaic virus (CYMV)

1 entry

Uncharacterized 10 kDa protein (ORF 6)

YOR6_NMV
Narcissus mosaic virus (NMV) reference strain