Ascovirus

VIRION

Virions consist of an envelope, a core, and an internal lipid membrane associated with the inner particle. Virion can be bacilliform, ovoidal or allantoid in shape, mesuring about 130 nm in diameter, by 200-400 nm in length. Contains at least 15 different proteins.

GENOME

Circular, dsDNA genome of 156-186 kb. The genome contains two tandem of inverted repeats.

GENE EXPRESSION

Encode for up to 180 open reading frames.

REPLICATION

NUCLEUS

  1. Attachment of the viral proteins to host receptors mediates endocytosis of the virus into the host cell.
  2. Fusion with the plasma membrane occurs; and the viral DNA is released into the nucleus.
  3. Transcription of viral genes, replication of the DNA genome in the nucleus.
  4. Cell nucleus enlarges and ruptures.
  5. Assembly of new virions in the cytoplasm.
  6. Host cell is cleaved in cluster of virion-containing vesicles.

Host-virus interaction

Apoptosis modulation

The Spodoptera frugiperda ascovirus encodes a viral caspase that is able to induce apoptosis in insect cells.

Matching UniProtKB/Swiss-Prot entries

34 entries grouped by protein (browse by keywords)

3 entries

Major capsid protein

Select_allDeselect_all
CAPSD_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain
CAPSD_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain
CAPSD_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Executioner caspase (EC 3.4.22.-)

CASP_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

2 entries

Caspase-like protein

Select_allDeselect_all
CSPL_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain
CSPL_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

3 entries

DNA polymerase (EC 2.7.7.7)

Select_allDeselect_all
DPOL_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain
DPOL_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain
DPOL_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

2 entries

Putative esterase (EC 3.1.1.-)

Select_allDeselect_all
ESTE_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain
ESTE_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

3 entries

Putative ATP-dependent RNA helicase (EC 3.6.4.13)

Select_allDeselect_all
HELI1_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain
HELI1_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain
HELI1_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

3 entries

Putative matrix metalloproteinase (EC 3.4.24.-)

Select_allDeselect_all
MMP_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain
MMP_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain
MMP_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Uncharacterized protein ORF11

Y011_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

1 entry

Uncharacterized protein ORF12

Y012_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

1 entry

Uncharacterized protein ORF17

Y017_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain

1 entry

Uncharacterized protein ORF18

Y018_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain

1 entry

Uncharacterized protein ORF42

Y042_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

2 entries

Structural protein ORF43

Select_allDeselect_all
Y043_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

Uncharacterized protein ORF43

Y043_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Uncharacterized protein ORF57

Y057_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain

1 entry

Uncharacterized protein ORF58

Y058_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain

1 entry

Uncharacterized protein ORF59

Y059_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain

1 entry

Putative structural protein ORF84

Y084_SFAVA
Spodoptera frugiperda ascovirus 1a (SfAV-1a) reference strain

1 entry

Structural protein ORF142

Y142_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Putative structural protein ORF146

Y146_HVAVE
Heliothis virescens ascovirus 3e (HvAV-3e) reference strain

1 entry

Structural protein ORF147

Y147_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Uncharacterized protein ORF148

Y148_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Uncharacterized protein ORF149

Y149_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain

1 entry

Uncharacterized protein ORF150

Y150_TNAVC
Trichoplusia ni ascovirus 2c (TnAV-2c) reference strain