Potyvirus

VIRION

Non-enveloped, flexuous, filamentous, of 720-850 nm long and 12-15 nm in diameter. Symmetry helical. Presence of characteristic inclusion bodies within infected plant cells.

GENOME

Monopartite, linear, ssRNA(+) genome of 10 kb in size. 3' terminus has a poly (A) tract. 5' terminus has a genome-linked protein (VPg).

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The genomic RNA is translated into polyproteins which are subsequently processed by the action of three viral-encoded proteinases into functional products. P3N-PIPO is expressed by polymerase slippage mechanism from the P3 ORF and probably acts as a movement protein .

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce a polyprotein which is processed by viral proteases into the RdRp protein and structural proteins.
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Virus assembly in the cytoplasm.
  7. Viral movement protein P3N-PIPO probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Potyviruses HC-PRO functions as a suppressor of RNA silencing .

Suppression of other plant defenses

VPg is a potent inhibitor of PAP depurination of RNA, thereby suppressing one of the plant defense mechanisms .

Matching UniProtKB/Swiss-Prot entries

49 entries grouped by protein (browse by keywords)

24 entries

P3N-PIPO polyprotein

Select_allDeselect_all
MVP_PVYN
Potato virus Y (strain N) (PVY) reference strain
MVP_BCMNN
Bean common mosaic necrosis virus (strain NL-3) (BCMNV) (Bean common mosaic virus serotype A (strain NL-3))
MVP_BTMV
Beet mosaic virus (BtMV)
MVP_BYMV
Bean yellow mosaic virus
MVP_LMV0
Lettuce mosaic virus (strain 0 / isolate French) (LMV)
MVP_LMVE
Lettuce mosaic virus (strain E) (LMV)
MVP_PEMVC
Pepper mottle virus (isolate California) (PeMV) (PepMoV C)
MVP_PEMVM
Peanut mottle virus (strain M)
MVP_PPVD
Plum pox potyvirus (strain D) (PPV)
MVP_PPVNA
Plum pox potyvirus (isolate NAT) (PPV)
MVP_PPVSK
Plum pox potyvirus (strain SK 68) (PPV)
MVP_PRSVH
Papaya ringspot virus (strain P / mutant HA)
MVP_PSBMV
Pea seed-borne mosaic virus (strain DPD1)
MVP_PVMA
Potato virus A (PVA)
MVP_PVYHU
Potato virus Y (strain Hungarian) (PVY)
MVP_SBMVG
Soybean mosaic virus (strain G2) (SMV)
MVP_SBMVN
Soybean mosaic virus (strain N) (SMV)
MVP_TEV
Tobacco etch virus (TEV)
MVP_TUMVJ
Turnip mosaic virus (strain Japanese) (TuMV)
MVP_TUMVQ
Turnip mosaic virus (strain Quebec) (TuMV)
MVP_TVMV
Tobacco vein mottling virus (TVMV)
MVP_ZYMVC
Zucchini yellow mosaic virus (strain California) (ZYMV)
MVP_ZYMVR
Zucchini yellow mosaic virus (strain Reunion Island) (ZYMV)
MVP_ZYMVS
Zucchini yellow mosaic virus (strain Singapore) (ZYMV)

25 entries

Genome polyprotein

Select_allDeselect_all
POLG_PVYN
Potato virus Y (strain N) (PVY) reference strain
POLG_BCMNN
Bean common mosaic necrosis virus (strain NL-3) (BCMNV) (Bean common mosaic virus serotype A (strain NL-3))
POLG_BTMV
Beet mosaic virus (BtMV)
POLG_BYMV
Bean yellow mosaic virus
POLG_LMV0
Lettuce mosaic virus (strain 0 / isolate French) (LMV)
POLG_LMVE
Lettuce mosaic virus (strain E) (LMV)
POLG_PEMVC
Pepper mottle virus (isolate California) (PeMV) (PepMoV C)
POLG_PEMVM
Peanut mottle virus (strain M)
POLG_PPVD
Plum pox potyvirus (strain D) (PPV)
POLG_PPVNA
Plum pox potyvirus (isolate NAT) (PPV)
POLG_PPVRA
Plum pox potyvirus (strain Rankovic) (PPV)
POLG_PPVSK
Plum pox potyvirus (strain SK 68) (PPV)
POLG_PRSVH
Papaya ringspot virus (strain P / mutant HA)
POLG_PSBMV
Pea seed-borne mosaic virus (strain DPD1)
POLG_PVMA
Potato virus A (PVA)
POLG_PVYHU
Potato virus Y (strain Hungarian) (PVY)
POLG_SBMVG
Soybean mosaic virus (strain G2) (SMV)
POLG_SBMVN
Soybean mosaic virus (strain N) (SMV)
POLG_TEV
Tobacco etch virus (TEV)
POLG_TUMVJ
Turnip mosaic virus (strain Japanese) (TuMV)
POLG_TUMVQ
Turnip mosaic virus (strain Quebec) (TuMV)
POLG_TVMV
Tobacco vein mottling virus (TVMV)
POLG_ZYMVC
Zucchini yellow mosaic virus (strain California) (ZYMV)
POLG_ZYMVR
Zucchini yellow mosaic virus (strain Reunion Island) (ZYMV)
POLG_ZYMVS
Zucchini yellow mosaic virus (strain Singapore) (ZYMV)