HIV-1 budding P6 protein (P6)

PTAP LYPXnL
FUNCTION
    As part of the Gag polyprotein, facilitates virus ESCRT-dependent budding through two distinct late assembly domains (L-domains) and allows incorporation of Vpr into virus particles .
INTERACTIONS
    Interacts with host Tsg101 and ALIX. Interacts with the viral protein Vpr (when phosphorylated).
SUBCELLULAR LOCATION
  • Virion
  • Cytoplasm
TIMING OF EXPRESSION
    Late