Potyvirus

VIRION

Non-enveloped, flexuous, filamentous, of 720-850 nm long and 12-15 nm in diameter. Symmetry helical. Presence of characteristic inclusion bodies within infected plant cells.

GENOME

Monopartite, linear, ssRNA(+) genome of 10 kb in size. 3' terminus has a poly (A) tract. 5' terminus has a genome-linked protein (VPg).

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The genomic RNA is translated into polyproteins which are subsequently processed by the action of three viral-encoded proteinases into functional products. P3N-PIPO is expressed by polymerase slippage mechanism from the P3 ORF and probably acts as a movement protein .

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce a polyprotein which is processed by viral proteases into the RdRp protein and structural proteins.
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Virus assembly in the cytoplasm.
  7. Viral movement protein P3N-PIPO probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Potyviruses HC-PRO functions as a suppressor of RNA silencing .

Suppression of other plant defenses

VPg is a potent inhibitor of PAP depurination of RNA, thereby suppressing one of the plant defense mechanisms .

Matching UniProtKB/Swiss-Prot entries

49 entries grouped by strain (browse by keywords)

2 entries

Potato virus Y (strain N) (PVY) reference strain

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MVP_PVYN P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_PVYN Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Bean common mosaic necrosis virus (strain NL-3) (BCMNV) (Bean common mosaic virus serotype A (strain NL-3))

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MVP_BCMNN P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_BCMNN Genome polyprotein [Cleaved into: P1 proteinase (N-terminal protein); Helper component proteinase ...

2 entries

Bean yellow mosaic virus

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MVP_BYMV P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_BYMV Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Beet mosaic virus (BtMV)

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MVP_BTMV P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_BTMV Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Lettuce mosaic virus (strain 0 / isolate French) (LMV)

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MVP_LMV0 P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_LMV0 Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Lettuce mosaic virus (strain E) (LMV)

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MVP_LMVE P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_LMVE Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Papaya ringspot virus (strain P / mutant HA)

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MVP_PRSVH P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_PRSVH Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Pea seed-borne mosaic virus (strain DPD1)

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MVP_PSBMV P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_PSBMV Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Peanut mottle virus (strain M)

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MVP_PEMVM P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_PEMVM Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Pepper mottle virus (isolate California) (PeMV) (PepMoV C)

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MVP_PEMVC P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_PEMVC Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Plum pox potyvirus (isolate NAT) (PPV)

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MVP_PPVNA P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_PPVNA Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Plum pox potyvirus (strain D) (PPV)

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MVP_PPVD P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_PPVD Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Plum pox potyvirus (strain SK 68) (PPV)

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MVP_PPVSK P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_PPVSK Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Potato virus A (PVA)

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MVP_PVMA P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_PVMA Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Potato virus Y (strain Hungarian) (PVY)

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MVP_PVYHU P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_PVYHU Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Soybean mosaic virus (strain G2) (SMV)

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MVP_SBMVG P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_SBMVG Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Soybean mosaic virus (strain N) (SMV)

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MVP_SBMVN P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_SBMVN Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Tobacco etch virus (TEV)

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MVP_TEV P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_TEV Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Tobacco vein mottling virus (TVMV)

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MVP_TVMV P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_TVMV Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Turnip mosaic virus (strain Japanese) (TuMV)

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MVP_TUMVJ P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_TUMVJ Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Turnip mosaic virus (strain Quebec) (TuMV)

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MVP_TUMVQ P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_TUMVQ Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Zucchini yellow mosaic virus (strain California) (ZYMV)

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MVP_ZYMVC P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_ZYMVC Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Zucchini yellow mosaic virus (strain Reunion Island) (ZYMV)

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MVP_ZYMVR P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_ZYMVR Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Zucchini yellow mosaic virus (strain Singapore) (ZYMV)

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MVP_ZYMVS P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_ZYMVS Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

1 entry

Plum pox potyvirus (strain Rankovic) (PPV)

POLG_PPVRA Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...