HIV virion

Virion composition

Science of HIV web site (movies)


Nucleic acids
Genomic viral RNA2 copies
tRNA Lys20 copies: about 8 tRNAlys3, and 12 tRNAlys1,2
spliced viral mRNA?
host SRP RNA/7SL ?
Unconfirmed: Host U6 RNA, host polIII RNA


Surface proteins
gp120/gp41 About 12-30
ICAM-1 ?
Proteins inside virion
Immature virion
Estimates with 61% complete Gag shell
Mature virion
Estimates with 61% complete Gag shell
Gag About 2500
(1400 , 2500 to 5000 )
-
Matrix-about 2500
(relative to Gag)
Capsid-one or two capsids composed of 1000-1500 CA proteins
Nucleoprotein-about 2500
(relative to Gag)
Gag-Pol About 120
(120 to 200 )
-
Protease-about 120
(relative to Gag-Pol)
Reverse transcriptaseabout 120
(relative to Gag-Pol)
Integrase-about 120
(relative to Gag-Pol)
Vpr 16-300?
(14-18 , or up to 300 )
16-300?
(14-18 , or up to 300 )
Host components
Actin about 280about 280
PPIA(CypA about 230about 230
Ezrin about 50about 50
Moesin about 50about 50
Unconfirmed components
ERK2???

Database of putative host proteins inside virion

The HIV resource is supported by the Swiss South Africa Joint Research Programme.