Tobamovirus

VIRION

Non-enveloped, rigid helical rods with a helical symmetry. Virion is about 18 nm in diameter, and 300-310 nm in length.

GENOME

Monopartite, linear, ssRNA(+) genome of 6.3-6.5 kb. The 3'-terminus has a tRNA-like structure. The 5' terminus has a methylated nucleotide cap (m7G5’pppG).

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The 5'-proximal ORFs are directly translated to produce the viral constituents of the replicase complex. RdRp is translated through suppression of termination at the end of ORF1. The small replicase is involved in replication and acts as a suppressor of RNA silencing. The movement proteins and the capsid protein are expressed from separate subgenomic mRNAs.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce the two proteins necessary for RNA synthesis (replication and transcription).
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. The RdRp recognizes internal subgenomic promoters on the negative-sense RNA to transcribe the 3’co-terminal subgenomic RNAs that will generate the capsid protein, movement protein(s) and viral suppressor of RNA silencing (VSR).
  7. Virus assembly in the cytoplasm. Each segment (if multipartite) is encapsidated.
  8. Viral movement protein probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Tobacco mosaic virus 126-kDa small replicase subunit suppresses RNA silencing .

Matching UniProtKB/Swiss-Prot entries

78 entries grouped by protein (browse by keywords)

All proteins are shown (view only 54 complete proteome entries)

35 entries

Capsid protein (Coat protein)

Select_allDeselect_all
CAPSD_CGMVS
Cucumber green mottle mosaic virus (strain watermelon SH) (CGMMV) reference strain
CAPSD_SHMV
Sunn-hemp mosaic virus (SHMV) (TMV strain cowpea) reference strain
CAPSD_TMGMV
Tobacco mild green mosaic virus (TMGMV) (TMV strain U2) reference strain
CAPSD_TMV
Tobacco mosaic virus (strain vulgare) (TMV) (Tobacco mosaic virus (strain U1)) reference strain
CAPSD_TVCV
Turnip vein-clearing virus (TVCV) reference strain
CAPSD_CGMVW
Cucumber green mottle mosaic virus (strain watermelon W) (CGMMV)
CAPSD_ORSVC
Odontoglossum ringspot virus (isolate Korean Cy) (ORSV-Cy)
CAPSD_ORSVJ
Odontoglossum ringspot virus (isolate Japan) (ORSV)
CAPSD_ORSVS
Odontoglossum ringspot virus (isolate Singapore 1) (ORSV)
CAPSD_PMMV
Paprika mild mottle virus (PaMMV)
CAPSD_PMMV0
Pepper mild mottle virus (strain P0) (PMMV)
CAPSD_PMMV1
Pepper mild mottle virus (strain P1) (PMMV)
CAPSD_PMMV2
Pepper mild mottle virus (strain P2) (PMMV)
CAPSD_PMMVI
Pepper mild mottle virus (strain Italian) (PMMV-I)
CAPSD_PMMVJ
Pepper mild mottle virus (strain Japan) (PMMV-J)
CAPSD_PMMVS
Pepper mild mottle virus (strain Spain) (PMMV-S)
CAPSD_RMV
Ribgrass mosaic virus (RMV)
CAPSD_RMVCA
Ribgrass mosaic virus (strain CAB) (RMV)
CAPSD_RMVHR
Ribgrass mosaic virus (strain Hr) (RMV) (TMV strain Holmes ribgrass)
CAPSD_TMOB
Tobamovirus Ob
CAPSD_TMV06
Tobacco mosaic virus (strain 06) (TMV-06)
CAPSD_TMVB
Tobacco mosaic virus (strain B935A) (TMV)
CAPSD_TMVDA
Tobacco mosaic virus (strain Dahlemense) (TMV)
CAPSD_TMVER
Tobacco mosaic virus (strain ER) (TMV)
CAPSD_TMVKO
Tobacco mosaic virus (strain Kokubu) (TMV)
CAPSD_TMVKR
Tobacco mosaic virus (strain Korean NC 82) (TMV)
CAPSD_TMVO
Tobacco mosaic virus (strain O) (TMV)
CAPSD_TMVOM
Tobacco mosaic virus (strain OM) (TMV)
CAPSD_TMVRA
Tobacco mosaic virus (strain Rakkyo) (TMV-R)
CAPSD_TOMK1
Tomato mosaic virus (strain Kazakh K1) (ToMV) (TMV strain K1)
CAPSD_TOMK2
Tomato mosaic virus (strain Kazakh K2) (ToMV) (TMV strain K2)
CAPSD_TOMKO
Tomato mosaic virus (strain Korean) (ToMV)
CAPSD_TOML
Tomato mosaic virus (strain L) (ToMV) (TMV strain tomato)
CAPSD_TOMS1
Tomato mosaic virus (strain S-1) (ToMV)
CAPSD_YOMV
Youcai mosaic virus (YoMV)

24 entries

Movement protein (30 kDa protein) (Cell-to-cell transport protein)

Select_allDeselect_all
MVP_CGMVS
Cucumber green mottle mosaic virus (strain watermelon SH) (CGMMV) reference strain

Movement protein (28.8 kDa protein) (Cell-to-cell transport protein)

MVP_SHMV
Sunn-hemp mosaic virus (SHMV) (TMV strain cowpea) reference strain
MVP_TMGMV
Tobacco mild green mosaic virus (TMGMV) (TMV strain U2) reference strain

Movement protein (28.5 kDa protein) (Cell-to-cell transport protein)

MVP_TMV
Tobacco mosaic virus (strain vulgare) (TMV) (Tobacco mosaic virus (strain U1)) reference strain
MVP_TVCV
Turnip vein-clearing virus (TVCV) reference strain
MVP_CGMVW
Cucumber green mottle mosaic virus (strain watermelon W) (CGMMV)

Movement protein (28.8 kDa protein) (Cell-to-cell transport protein)

MVP_ORSVC
Odontoglossum ringspot virus (isolate Korean Cy) (ORSV-Cy)

Movement protein (33.4 kDa protein) (Cell-to-cell transport protein)

MVP_ORSVJ
Odontoglossum ringspot virus (isolate Japan) (ORSV)

Movement protein (33.4 kDa protein) (Cell-to-cell transport protein)

MVP_ORSVS
Odontoglossum ringspot virus (isolate Singapore 1) (ORSV)
MVP_PMMVJ
Pepper mild mottle virus (strain Japan) (PMMV-J)
MVP_PMMVS
Pepper mild mottle virus (strain Spain) (PMMV-S)
MVP_RMV
Ribgrass mosaic virus (RMV)
MVP_TMOB
Tobamovirus Ob
MVP_TMVB
Tobacco mosaic virus (strain B935A) (TMV)
MVP_TMVKR
Tobacco mosaic virus (strain Korean NC 82) (TMV)
MVP_TMVOM
Tobacco mosaic virus (strain OM) (TMV)
MVP_TMVRA
Tobacco mosaic virus (strain Rakkyo) (TMV-R)
MVP_TOMK1
Tomato mosaic virus (strain Kazakh K1) (ToMV) (TMV strain K1)
MVP_TOMK2
Tomato mosaic virus (strain Kazakh K2) (ToMV) (TMV strain K2)
MVP_TOML
Tomato mosaic virus (strain L) (ToMV) (TMV strain tomato)
MVP_TOML2
Tomato mosaic virus (strain LII) (ToMV)
MVP_TOMLA
Tomato mosaic virus (strain LIIa) (ToMV)
MVP_TOMS1
Tomato mosaic virus (strain S-1) (ToMV)
MVP_YOMV
Youcai mosaic virus (YoMV)

19 entries

Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) (RNA-directed RNA polymerase)

Select_allDeselect_all
RDRP_CGMVS
Cucumber green mottle mosaic virus (strain watermelon SH) (CGMMV) reference strain

Replicase large subunit (EC 2.7.7.48) (186 kDa protein)

RDRP_SHMV
Sunn-hemp mosaic virus (SHMV) (TMV strain cowpea) reference strain
RDRP_TMGMV
Tobacco mild green mosaic virus (TMGMV) (TMV strain U2) reference strain
RDRP_TMV
Tobacco mosaic virus (strain vulgare) (TMV) (Tobacco mosaic virus (strain U1)) reference strain
RDRP_TMVOM
Tobacco mosaic virus (strain OM) (TMV) reference strain
RDRP_TVCV
Turnip vein-clearing virus (TVCV) reference strain
RDRP_ORSVC
Odontoglossum ringspot virus (isolate Korean Cy) (ORSV-Cy)
RDRP_ORSVS
Odontoglossum ringspot virus (isolate Singapore 1) (ORSV)
RDRP_PMMVJ
Pepper mild mottle virus (strain Japan) (PMMV-J)
RDRP_PMMVS
Pepper mild mottle virus (strain Spain) (PMMV-S)
RDRP_TMOB
Tobamovirus Ob
RDRP_TMVB
Tobacco mosaic virus (strain B935A) (TMV)
RDRP_TMVKR
Tobacco mosaic virus (strain Korean NC 82) (TMV)
RDRP_TMVRA
Tobacco mosaic virus (strain Rakkyo) (TMV-R)
RDRP_TOMK1
Tomato mosaic virus (strain Kazakh K1) (ToMV) (TMV strain K1)
RDRP_TOMK2
Tomato mosaic virus (strain Kazakh K2) (ToMV) (TMV strain K2)
RDRP_TOML
Tomato mosaic virus (strain L) (ToMV) (TMV strain tomato)
RDRP_TOMS1
Tomato mosaic virus (strain S-1) (ToMV)
RDRP_YOMV
Youcai mosaic virus (YoMV)

Replicase large subunit (EC 2.7.7.48) (182 kDa protein)