Ostreavirus

VIRION

Enveloped, spherical to pleomorphic, 150-200 nm in diameter, T=16 icoseadral symmetry. Capsid consists of 162 capsomers. Glycoproteins complexes are embeded in the lipid envelope.

GENOME

Monopartite, linear, dsDNA genome of 134 kb. The genome contains terminal and internal reiterated sequences.

GENE EXPRESSION

Each viral transcript usually encodes a single protein and has a promoter/regulatory sequence, a TATA box, a transcription initiation site, a 5' leader sequence of 30-300 bp (not translated), a 3' nontranslated sequence of 10-30 bp, and a poly A signal. There are many gene overlaps. There are only few spliced genes. Some of the expressed ORFs are antisense to each other. Some ORFs can be accessed from more than one promoter. There are some non-coding genes.

REPLICATION

NUCLEAR

Lytic replication:

  1. Virus attaches to host receptors through gB, gC, gD and gH .
  2. Fusion with the plasma membrane to release the core and the tegument proteins into the host cytoplasm.
  3. The capsid is transported to the nuclear pore where the viral DNA is released into the nucleus.
  4. Transcription of immediate early genes which promote transcription of early genes.
  5. Transcription of early viral mRNA by host polymerase II, transport into the cytoplasm and translation into early proteins.
  6. Early proteins are involved in replication of the viral DNA and are transported back into the nucleus.
  7. Synthesis of multiple copies of viral DNA by the viral DNA-dependent DNA polymerase.
  8. Transcription of late mRNAs by host polymerase II, transport into the cytoplasm and translation into late proteins.
  9. Late proteins are structural or core proteins and are transported back into the nucleus.
  10. Assembly of the virus and budding through the inner lamella of the nuclear membrane which has been modified by the insertion of herpes glycoproteins, throughout the Golgi and final release at the plasma membrane.

Latent replication : replication of circular viral episome in tandem with the host cell DNA using the host cell replication machinery.

Matching UniProtKB/Swiss-Prot entries

114 entries grouped by protein (browse by keywords)

1 entry

DNA polymerase (EC 2.7.7.7)

DPOL_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative apoptosis inhibitor ORF42

IAP1_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative apoptosis inhibitor ORF87

IAP2_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative apoptosis inhibitor ORF99

IAP3_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative apoptosis inhibitor ORF106

IAP4_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative primase (EC 2.7.7.-)

PRIM_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1)

RIR1_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1)

RIR2_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF1

Y001_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF2

Y002_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF3

Y003_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF4

Y004_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF6

Y006_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF8

Y008_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative RING finger protein ORF9

Y009_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF10

Y010_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF12

Y012_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF13

Y013_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF14

Y014_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF15

Y015_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF16

Y016_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF17

Y017_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF18

Y018_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF19

Y019_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF21

Y021_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF22

Y022_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF23

Y023_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF24

Y024_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative transmembrane protein ORF25

Y025_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF26

Y026_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF27

Y027_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF28

Y028_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF29

Y029_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF30

Y030_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF31

Y031_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF33

Y033_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF34

Y034_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF35

Y035_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF36

Y036_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF37

Y037_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative RING finger protein ORF38

Y038_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF39

Y039_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF40

Y040_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF41

Y041_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF43

Y043_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF44

Y044_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF45

Y045_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF46

Y046_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF47

Y047_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF48

Y048_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF49

Y049_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF52

Y052_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF53

Y053_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF54

Y054_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF55

Y055_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF56

Y056_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative transmembrane protein ORF57

Y057_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF58

Y058_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF59

Y059_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF60

Y060_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF61

Y061_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF64

Y064_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF67

Y067_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative transmembrane protein ORF68

Y068_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF69

Y069_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF70

Y070_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF71

Y071_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF72

Y072_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF74

Y074_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF75

Y075_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF76

Y076_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF77

Y077_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF78

Y078_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF79

Y079_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF80

Y080_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF81

Y081_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF82

Y082_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF83

Y083_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF84

Y084_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF85

Y085_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF86

Y086_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative transmembrane protein ORF88

Y088_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF89

Y089_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF90

Y090_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF91

Y091_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF92

Y092_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF93

Y093_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF94

Y094_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF95

Y095_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative RING finger protein ORF96

Y096_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative RING finger protein ORF97

Y097_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF98

Y098_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF101

Y101_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF102

Y102_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative transmembrane protein ORF103

Y103_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF104

Y104_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF107

Y107_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF108

Y108_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF109

Y109_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF110

Y110_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative transmembrane protein ORF111

Y111_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF112

Y112_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF113

Y113_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF114

Y114_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF115

Y115_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF116

Y116_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative RING finger protein ORF117

Y117_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative RING finger protein ORF118

Y118_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF119

Y119_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF120

Y120_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Putative zinc finger protein ORF121

Y121_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF122

Y122_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF123

Y123_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain

1 entry

Uncharacterized protein ORF124

Y124_OSHVF
Ostreid herpesvirus 1 (isolate France) (OsHV-1) (Pacific oyster herpesvirus) reference strain