Tectivirus

VIRION

Non enveloped, icosahedral virion with a pseudo T=25 symmetry, consisting of 240 capsid proteins trimers. Virion size is about 66 nm with apical spikes of 20 nm. The capsid encloses a inner membrane vesicle within which the genomic DNA is coiled.

GENOME

Linear, dsDNA genome of about 15 kb flanked by inverted repeats. Encodes for 30 ORFs. Replication is protein-primed.

GENE EXPRESSION

Genes are transcribed by operons.

REPLICATION

CYTOPLASMIC

  1. Adsorption: The phage attaches to target cell adhesion receptors through its spike protein P2. As a result, a protein complex composed of P2, P5, P31 and a part of the capsid (p3) is released, which produces a hole in the capsid.
  2. Internal phage membrane transforms into a tubular structure that protrudes through a hole in the capsid and penetrates the host outer membrane and peptidoglycan layer. This membrane tube then fuses with host plasma membrane, releasing the viral DNA into the cytoplasm.
  3. Transcription and translation of early genes.
  4. Replication of genomic DNA.
  5. Transcription and translation of late genes.
  6. Capsid proteins polymerize around a lipoprotein vesicle translocated in the cytoplasm by virion assembly factors.
  7. Genomic DNA is packaged in new virions.
  8. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

25 entries grouped by strain (browse by keywords)

25 entries

Enterobacteria phage PRD1 (Bacteriophage PRD1) reference strain

Select_allDeselect_all
CAPSD_BPPRD Major capsid protein P3 (Protein P3)
EXLYS_BPPRD Transglycosylase (EC 4.2.2.n1) (Protein P7)
DPOL_BPPRD DNA-directed DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Protein P1)
ENLYS_BPPRD Endolysin (EC 3.2.1.17) (Beta-1,4-N-acetylmuramidase) (Lysozyme) (Lytic enzyme) (Muramidase) ...
PKG6_BPPRD Packaging efficiency factor P6
TERM_BPPRD DNA terminal protein (Protein P8)
HOLIN_BPPRD Holin (Protein P35)
P5_BPPRD Spike protein P5 (Protein P5)
P2_BPPRD Adsorption protein P2 (Protein P2)
PKG20_BPPRD Packaging protein P20
PKG22_BPPRD Packaging protein P22 (GpK) (Protein K)
PKG9_BPPRD DNA packaging ATPase P9 (Protein P9)
VP34_BPPRD Protein P34 (Protein O) (GpO)
VP33_BPPRD Protein P33
VP12_BPPRD Single-stranded DNA-binding protein (Protein P12)
VP16_BPPRD Protein P16 (GpS) (Protein S)
VP30_BPPRD Minor capsid protein P30 (Protein P) (GpP)
VP10_BPPRD Protein P10
VP18_BPPRD Protein P18 (GpM) (Protein M)
VP17_BPPRD Protein P17
VP31_BPPRD Penton protein P31 (GpC) (Protein C)
VP11_BPPRD Infectivity protein P11
VP19_BPPRD Protein P19
VP32_BPPRD Protein P32
YPI_BPPRD Putative uncharacterized 4.5 kDa protein in genes IX-XX intergenic region (ORFi)