Syncytium formation induced by viral infection

Syncytia is formed by fusion of an infected cells with neighboring cells leading to the formation of multi-nucleate enlarged cells. This event is induced by surface expression of viral fusion protein that are fusogenic directly at the host cell membrane.
Syncytia canonly happen with viruses able to directly fuse at the cellular surface without the need of endocytosis.

Matching UniProtKB/Swiss-Prot entries

21 entries grouped by strain (browse by keywords)

All proteins are shown (view only 10 complete proteome entries)

1 entry

Bovine respiratory syncytial virus (strain A51908) (BRS) reference strain

FUS_BRSVA Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2'; Interchain peptide; Fusion ...

1 entry

Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus) reference strain

GK_EHV1B Envelope glycoprotein K (Syncytial protein)

1 entry

Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease herpesvirus type 1) reference strain

GK_GAHVM Envelope glycoprotein K

1 entry

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) reference strain

GK_HHV11 Envelope glycoprotein K (Syncytial protein)

1 entry

Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) reference strain

GK_HHV2H Envelope glycoprotein K (Syncytial protein)

1 entry

Human respiratory syncytial virus B (strain B1) reference strain

FUS_HRSVB Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2'; Interchain peptide; ...

1 entry

Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1) (Pacheco's disease virus) reference strain

GK_PSHV1 Envelope glycoprotein K (Syncytial protein)

1 entry

Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3) reference strain

GK_VZVD Envelope glycoprotein K (Syncytial protein)

1 entry

Bovine respiratory syncytial virus (strain Copenhagen) (BRS)

FUS_BRSVC Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2'; Interchain peptide; Fusion ...

1 entry

Bovine respiratory syncytial virus (strain Rb94) (BRS)

FUS_BRSVR Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2'; Interchain peptide; Fusion ...

1 entry

Equine herpesvirus 1 (strain Kentucky A) (EHV-1) (Equine abortion virus)

GK_EHV1K Envelope glycoprotein K (Syncytial protein)

1 entry

Human herpesvirus 1 (strain KOS) (HHV-1) (Human herpes simplex virus 1)

GK_HHV1K Envelope glycoprotein K (Syncytial protein)

1 entry

Human herpesvirus 1 (strain MP) (HHV-1) (Human herpes simplex virus 1)

GK_HHV1M Envelope glycoprotein K (Syncytial protein)

1 entry

Human herpesvirus 1 (strain R15) (HHV-1) (Human herpes simplex virus 1)

GK_HHV1R Envelope glycoprotein K (Syncytial protein)

1 entry

Human herpesvirus 1 (strain R19) (HHV-1) (Human herpes simplex virus 1)

GK_HHV19 Envelope glycoprotein K (Syncytial protein)

1 entry

Human respiratory syncytial virus A (strain A2)

FUS_HRSVA Fusion glycoprotein F0 (Protein F) [Cleaved into: Fusion glycoprotein F2'; Interchain peptide; ...

1 entry

Human respiratory syncytial virus A (strain Long)

FUS_HRSVL Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2'; Interchain peptide; Fusion ...

1 entry

Human respiratory syncytial virus A (strain RSS-2)

FUS_HRSVR Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2'; Interchain peptide; Fusion ...

1 entry

Human respiratory syncytial virus B (strain 18537)

FUS_HRSV1 Fusion glycoprotein F0 [Cleaved into: Fusion glycoprotein F2'; Interchain peptide; Fusion ...

1 entry

Suid herpesvirus 1 (strain Kaplan) (SuHV-1) (Pseudorabies virus (strain Kaplan))

GK_SUHVK Envelope glycoprotein K (Syncytial protein)

1 entry

Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)

GK_VZVO Envelope glycoprotein K (Syncytial protein)