Fimoviridae

VIRION

Enveloped, spherical.

GENOME

The genome is segmented and consists of four segments of linear negative-sense and single-stranded RNA. The complete genome is around 12.2 kb.

GENE EXPRESSION

The viral RNA dependent RNA polymerase (L) binds to a promoter on each encapsidated segment, and transcribes the mRNAs. These are capped by L protein during synthesis using cap snatching

REPLICATION

CYTOPLASMIC

  1. Virus attaches to host receptors.
  2. Fusion of virus membrane with the cell membrane; ribonucleocapsid segments are released in the cell.
  3. Transcription, viral mRNAs are capped in the cytoplasm.
  4. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  5. The ribonucleocapsids buds from a cellular membrane, releasing the virion.

Matching UniProtKB/Swiss-Prot entries

4 entries grouped by protein (browse by keywords)

1 entry

Envelope glycoprotein (GP)

GLYC_EMARV
European mountain ash ringspot-associated virus (isolate Sorbus aucuparia) (EMARAV) reference strain

1 entry

RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) (Transcriptase)

L_EMARV
European mountain ash ringspot-associated virus (isolate Sorbus aucuparia) (EMARAV) reference strain

1 entry

Nucleoprotein (NP) (Nucleocapsid protein) (Protein N)

NCAP_EMARV
European mountain ash ringspot-associated virus (isolate Sorbus aucuparia) (EMARAV) reference strain

1 entry

Uncharacterized 27 kDa protein

VG27_EMARV
European mountain ash ringspot-associated virus (isolate Sorbus aucuparia) (EMARAV) reference strain