Botrexvirus

VIRION

Non-enveloped, flexuous, filamentous virion, about 720 nm long and 12-13 nm in diameter.

GENOME

Linear ssRNA(+) genome of about 7 kb in size. The 3' terminus is polyadenylated and the 5' end is capped. Encodes 5 proteins.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. RNA-dependent RNA polymerase (RdRp) is translated directly from the genomic RNA. The other ORFs are transcribed presumably as monocistronic subgenomic mRNAs (sgRNAs).

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated as a monocistronic mRNA to produce the RdRp (encoded by the 5'-proximal ORF).
  4. Replication occurs in viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Internal subgenomic promoters are used to transcribe the sgRNAs. Traduction of these sgRNAs yields the capsid and movement proteins.
  7. Assembly of new virus particles.

Matching UniProtKB/Swiss-Prot entries

5 entries grouped by strain (browse by keywords)

5 entries

Botrytis virus X (isolate Botrytis cinerea/New Zealand/Howitt/2006) (BOTV-X) reference strain

Select_allDeselect_all
CAPSD_BOTVX Capsid protein (CP)
ORF4_BOTVX Uncharacterized ORF4 protein
ORF5_BOTVX Uncharacterized ORF5 protein
ORF2_BOTVX Uncharacterized ORF2 protein
RDRP_BOTVX RNA replication protein [Includes: RNA-directed RNA polymerase (EC 2.7.7.48); Helicase (EC ...