Vespertiliovirus

VIRION

Non-enveloped, rod of filaments of 7 nm in diameter and 1000 to 1200nm long in length. Helical capsid with adsorption proteins on one end.

GENOME

Circular, ssDNA genome (+) of 6.3 to 7.5 kb encoding for 12 to 15 proteins. Replication occurs via dsDNA intermediate and rolling circle.

GENE EXPRESSION

Each gene is transcribed by host cellular machinery, via a specific promoter. Some genes end by a transcription terminator.



REPLICATION

CYTOPLASMIC

  1. Virus mediates pilus-mediated adsorption of the virus onto host cell. Pilus retraction pulls the virion to the host internal membrane.
  2. The proteins of the capsid perform the injection of the viral DNA through bacterial membranes into cell cytoplasm.
  3. Host polymerase convert the (+)ssDNA viral genome into a covalently closed dsDNA called replicative form DNA (RF).
  4. dsDNA transcription by host RNA polymerase gives rise to viral mRNAs.
  5. A viral protein may nick RF DNA strand at the origin of replication.
  6. (+) strand replication occurs by rolling circle.
  7. New (+)ssDNA genomes are converted into new RF molecules, and further transcription occurs.
  8. A conversion into RF dsDNA is inhibited, as neo-synthesized genomic ssDNA is covered with a viral protein.
  9. Assembly of the viral capsid.
  10. New virions are secreted from host cell.
  11. Infected cells continue to divide and produce virions indefinitely.

Matching UniProtKB/Swiss-Prot entries

25 entries grouped by protein (browse by keywords)

2 entries

Putative capsid protein ORF9

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CAPSD_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain
CAPSD_SPV1R
Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1) reference strain

Putative capsid protein ORF9 (Gene 9 protein)

2 entries

Putative integrase ORF3

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INTG_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain
INTG_SPV1R
Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1) reference strain

Putative integrase ORF3 (Gene 3 protein)

2 entries

Uncharacterized protein ORF1

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ORF1_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain
ORF1_SPV1R
Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1) reference strain

Uncharacterized protein ORF1 (Gene 1 protein)

2 entries

Uncharacterized protein ORF10

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ORF10_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain
ORF10_SPV1R
Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1) reference strain

Uncharacterized protein ORF10 (Gene 10 protein)

2 entries

Uncharacterized protein ORF11

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ORF11_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain
ORF11_SPV1R
Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1) reference strain

Uncharacterized protein ORF11 (Gene 11 protein)

2 entries

Uncharacterized protein ORF12

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ORF12_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain
ORF12_SPV1R
Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1) reference strain

Uncharacterized protein ORF12 (Gene 12 protein)

1 entry

Uncharacterized protein ORF13

ORF13_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain

1 entry

Uncharacterized protein ORF14

ORF14_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain

1 entry

Uncharacterized protein ORF15

ORF15_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain

2 entries

Uncharacterized protein ORF2

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ORF2_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain
ORF2_SPV1R
Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1) reference strain

Uncharacterized protein ORF2 (Gene 2 protein)

2 entries

Uncharacterized protein ORF4

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ORF4_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain
ORF4_SPV1R
Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1) reference strain

Uncharacterized protein ORF4 (Gene 4 protein)

2 entries

Uncharacterized protein ORF5

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ORF5_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain
ORF5_SPV1R
Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1) reference strain

Uncharacterized protein ORF5 (Gene 5 protein)

1 entry

Uncharacterized protein ORF6 (Gene 6 protein)

ORF6_SPV1R
Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1) reference strain

2 entries

Uncharacterized protein ORF7

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ORF7_SPV1C
Spiroplasma virus SpV1-C74 (SpV1) reference strain
ORF7_SPV1R
Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1) reference strain

Uncharacterized protein ORF7 (Gene 7 protein)

1 entry

Uncharacterized protein ORF8 (Gene 8 protein)

ORF8_SPV1R
Spiroplasma virus SpV1-R8A2 B (SpV1) (Spiroplasma virus 1) reference strain