Cytorhabdovirus

VIRION

Enveloped, bullet shaped. 180 nm long and 75 nm wide. Certain plant rhabdoviruses are bacilliform in shape and almost twice the length.

GENOME

Negative-stranded RNA linear genome, about 13 kb in size. Encodes for six (LNYV) to nine (NCMV) proteins.

GENE EXPRESSION

The viral RNA dependent RNA polymerase binds the encapsidated genome at the leader region, then sequentially transcribes each genes by recognizing start and stop signals flanking viral genes. mRNAs are capped and polyadenylated by the L protein during synthesis.

REPLICATION

CYTOPLASMIC

  1. Attachment of the viral G glycoproteins to host receptors.
  2. Fusion of virus membrane with the vesicle membrane; ribonucleocapsid is released into the cytoplasm.
  3. Sequential transcription , viral mRNAs are capped and polyadenylated by polymerase stuttering in the cytoplasm.
  4. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  5. The ribonucleocapsid can penetrate in neighboring cells through plasmodesmata transport
  6. The ribonucleocapsid binds to the matrix protein and budding of particles occurs at the cell membrane, releasing new virions.

Host-virus interaction

Movement through plasmodesmata

Viral movement protein

Viral movement protein presumably interacts with host plasmodesmata to allow tubule guided movement of viral genomic material from cell to cell without budding.

Matching UniProtKB/Swiss-Prot entries

14 entries grouped by protein (browse by keywords)

2 entries

Glycoprotein

Select_allDeselect_all
GLYCO_LNYV3
Lettuce necrotic yellows virus (isolate 318) (LNYV) reference strain
GLYCO_NCMV
Northern cereal mosaic virus (NCMV) reference strain

1 entry

RNA-directed RNA polymerase L (Protein L) (Large structural protein) (Replicase) (Transcriptase)

L_LNYV3
Lettuce necrotic yellows virus (isolate 318) (LNYV) reference strain

2 entries

Matrix protein

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MATRX_LNYV3
Lettuce necrotic yellows virus (isolate 318) (LNYV) reference strain
MATRX_NCMV
Northern cereal mosaic virus (NCMV) reference strain

1 entry

Probable movement protein 4b (MP) (Cell-to-cell transport protein) (Protein 4b)

MVP_LNYV3
Lettuce necrotic yellows virus (isolate 318) (LNYV) reference strain

2 entries

Nucleoprotein (NP) (Nucleocapsid protein) (Protein N)

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NCAP_LNYV3
Lettuce necrotic yellows virus (isolate 318) (LNYV) reference strain
NCAP_NCMV
Northern cereal mosaic virus (NCMV) reference strain

1 entry

Phosphoprotein (Protein P) (Protein M1)

PHOSP_NCMV
Northern cereal mosaic virus (NCMV) reference strain

1 entry

Protein 3

VP3_NCMV
Northern cereal mosaic virus (NCMV) reference strain

1 entry

Protein 4

VP4_NCMV
Northern cereal mosaic virus (NCMV) reference strain

1 entry

Phosphoprotein (Protein P) (Protein 4a)

VP4A_LNYV3
Lettuce necrotic yellows virus (isolate 318) (LNYV) reference strain

1 entry

Protein 5

VP5_NCMV
Northern cereal mosaic virus (NCMV) reference strain

1 entry

Protein 6

VP6_NCMV
Northern cereal mosaic virus (NCMV) reference strain