Peropuvirus

VIRION

Enveloped, spherical. Diameter from 70 to 100nm.

GENOME

Negative-stranded RNA linear genome, about 12.3 kb in size. Encodes for five proteins.

GENE EXPRESSION

The viral RNA dependent RNA polymerase binds the encapsidated genome at the leader region, then sequentially transcribes each genes by recognizing start and stop signals flanking viral genes.

REPLICATION

CYTOPLASM

  1. Attachement of the viral glycoproteins to host receptors.
  2. Fusion of virus membrane with the vesicle membrane.
  3. Sequential transcription.
  4. Replication .
  5. Cytoplasmic ribo-nucleocapsids buds out of the cell,releasing new virions.