Alphanudivirus

VIRION

Rod-shaped, enveloped virion up to 400x100nm

GENOME

Circular, dsDNA genome of 97-128 kb.

GENE EXPRESSION

The genome encodes from 98 to 140 open reading frames .

REPLICATION

NUCLEUS

  1. Virus attaches to host receptors, and is internalized by pinocytosis.
  2. Fusion of virus membrane with the vesicle membrane occurs; DNA genome is released into the nucleus.
  3. Transcription of viral genes, replication of the DNA genome in the nucleus.
  4. Cell nucleus enlarges and ruptures.
  5. Assembly of new virions in the cytoplasm.
  6. Virions bud from the cell membrane.