Phicbkvirus

VIRION

Non-enveloped, head-tail structure. The prolate head is about 205 nm by 60 nm. Tail length is about 350 nm.

GENOME

Linear, dsDNA genome of about 205-213 kb with approximately 10 kb terminal repeats, containing about 318 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
  2. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
  3. DNA genome is circularized or integrated into host chromosome
  4. Transcription and translation of early genes
  5. Replication of genomic DNA.
  6. Transcription and translation of late genes
  7. Assembly of an empty procapsid and packaging of the genome.
  8. Viral tail fiber assembly and viral tail assembly.
  9. Mature virions are released from the cell by lysis.