Reptarenavirus (taxid:1653395)

VIRION

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Enveloped, spherical. Diameter from 60 to 300 nm.

GENOME

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Segmented Negative-stranded RNA linear genome, L segment is about 6.9 kb and S segment 3.4 kb.
Encodes four proteins.

GENE EXPRESSION

Both segments are ambisens. The viral RNA dependent RNA polymerase (L) binds to a promoter on each encapsidated segment, and transcribes a messenger RNA. Transcription is terminated by a strong hairpin sequence at the end of each gene. mRNAs are capped, probably by L protein during synthesis.

ENZYMES

REPLICATION

CYTOPLASM

  1. Virus attaches to host receptors though GP glycoprotein and is endocytosed into vesicles in the host cell by apoptotic mimicry.
  2. Fusion of virus membrane with the vesicle membrane; ribonucleocapsid is released in the cytoplasm.
  3. Sequential transcription, viral mRNAs are capped in the cytoplasm.
  4. Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
  5. The ribonucleocapsid interacts with the Z protein under the plasma membrane and buds, releasing the virion.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

4 entries grouped by strain

4 entries

Alethinophid 1 reptarenavirus (isolate AlRrV1/Boa/USA/BC/2009) (Golden Gate virus) reference strain

Select_allDeselect_all
L_GOGV RNA-directed RNA polymerase L (Protein L) (EC 2.7.7.48) (Large structural protein) (Replicase) ...
NCAP_GOGV Nucleoprotein (Nucleocapsid protein) (Protein N)
GLYC_GOGV Glycoprotein
MEM_GOGV Putative membrane protein