Bacterial host gene expression shutoff by virus

Bacterial viruses are in competition with the host for the cellular replication, transcription or translation machinery, prompting many of them to inhibit host cell gene expression. To achieve this goal, they possess a wide array of mechanisms that inactivate host transcription or even completely degrade the host chromosome.

degradation chromosome transcription shutoff

Matching UniProtKB/Swiss-Prot entries

12 entries grouped by strain (browse by keywords)

4 entries

Enterobacteria phage T4 (Bacteriophage T4) reference strain

ALC_BPT4 Protein alc (Protein unf)
EXO1_BPT4 Exonuclease subunit 1 (EC 3.1.11.-) (Gene product 47) (gp47)
EXO2_BPT4 Exonuclease subunit 2 (EC 3.1.11.-) (Gene product 46) (gp46)
END2_BPT4 Endonuclease II (EC

4 entries

Escherichia phage T7 (Bacteriophage T7) reference strain

PK_BPT7 Protein kinase 0.7 (EC (Gene product 0.7) (Gp0.7) (Protein kinase gp0.7)
VRPI_BPT7 Bacterial RNA polymerase inhibitor (Gene product 2) (Gp2)
ENDO_BPT7 Endonuclease I (EC (Gene product 3) (Gp3) (Junction-resolving enzyme gp3)
EXRN_BPT7 Exonuclease (Exonuclease gp6) (Gene product 6) (Gp6) (EC

3 entries

Escherichia phage T5 (Enterobacteria phage T5) reference strain

A1_BPT5 Protein A1
EXO2_BPT5 Probable exonuclease subunit 2 (EC 3.1.11.-) (D13)
EXO1_BPT5 Probable exonuclease subunit 1 (EC 3.1.11.-) (D12)

1 entry

Enterobacteria phage T3 (Bacteriophage T3)

VRPI_BPT3 Bacterial RNA polymerase inhibitor (Gene product 2) (Gp2)