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Bacterial host gene expression shutoff by virus (kw:KW-1261)

Bacterial viruses are in competition with the host for the cellular replication, transcription or translation machinery, prompting many of them to inhibit host cell gene expression. To achieve this goal, they possess a wide array of mechanisms that inactivate host transcription or even completely degrade the host chromosome.

degradation chromosome transcription shutoff

Viral molecular biology Virus entry
Virus latency
Transcription and replication
Host-virus interactions
Virus exit
Host cell shutoff Degradation of host chromosome
Transcription shutoff
Links Uniprot Keyword: KW-1190
GO ontology:GO:0039657

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

13 entries grouped by strain

4 entries

Enterobacteria phage T4 (Bacteriophage T4) reference strain

Select_allDeselect_all
END2_BPT4 Endonuclease II (EC 3.1.21.8)

pdb 2WSH

EXO1_BPT4 Exonuclease subunit 1 (EC 3.1.11.-) (Gene product 47) (gp47)
EXO2_BPT4 Exonuclease subunit 2 (EC 3.1.11.-) (Gene product 46) (gp46)
ALC_BPT4 Protein alc (Protein unf)

4 entries

Escherichia phage T5 (Enterobacteria phage T5) reference strain

Select_allDeselect_all
EXO2_BPT5 Probable exonuclease subunit 2 (EC 3.1.11.-) (D13)
APNUC_BPT5 DNA-(apurinic or apyrimidinic site) endonuclease (EC 3.1.-.-) (AP endonuclease) ...
A1_BPT5 Protein A1
EXO1_BPT5 Probable exonuclease subunit 1 (EC 3.1.11.-) (D12)

4 entries

Escherichia phage T7 (Bacteriophage T7) reference strain

Select_allDeselect_all
PK_BPT7 Protein kinase 0.7 (EC 2.7.11.1) (Gene product 0.7) (Gp0.7) (Protein kinase gp0.7)
ENDO_BPT7 Endonuclease I (EC 3.1.21.2) (Gene product 3) (Gp3) (Junction-resolving enzyme gp3)

pdb 1FZR; 1M0D; 1M0I; 2PFJ; 3CAE

EXRN_BPT7 Exonuclease (Exonuclease gp6) (Gene product 6) (Gp6) (EC 3.1.11.3)
VRPI_BPT7 Bacterial RNA polymerase inhibitor (Gene product 2) (Gp2)

pdb 2LMC; 2WNM; 4LK0; 4LLG

1 entry

Enterobacteria phage T3 (Bacteriophage T3)

VRPI_BPT3 Bacterial RNA polymerase inhibitor (Gene product 2) (Gp2)