Chloriridovirus

VIRION

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Polyhedral virions 180 nm in diameter. The capsid displays an icosahedral symmetry T=189-217, with an internal lipid membrane. Virions are either externally enveloped or not depending whether they budded from the cell membrane, or were arranged in paracrystaline array in the host cell cytoplasm and were released by lysis.

GENOME

Linear, dsDNA genome of about 135 kb. The genome contains terminal and redundant sequences and is circularly permuted. Encodes for about 126 proteins. The genome is not methylated.

GENE EXPRESSION

REPLICATION

NUCLEO-CYTOPLASMIC

  1. Attachment of the viral proteins to host receptors mediates endocytosis of the virus into the host cell.
  2. Fusion with the plasma membrane to release the DNA core into the host cytoplasm.
  3. Viral DNA is transported to the cell nucleus where host macromolecular synthesis is rapidly shutdown. Transcription is initiated by virally modified host RNA polymerase II.
  4. Parental DNA is used to produce genome and greater than genome length DNA.
  5. Progeny DNA is transported into cytoplasmic viral factories where large concatamers of viral DNA are formed by recombination. Transcription of very late transcripts may also take place in the cytoplasm.
  6. Assembly of new virions in the cytoplasm.
  7. Virions exit the cell by budding or cell lysis.

Host-virus interaction

Apoptosis modulation

Invertebrate iridescent virus 3 encodes a protein homolog to the Chilo iridescent virus functional inhibitor of apoptosis (IAP) . This ORF may therefore play a role in the modulation of host apoptosis.

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

129 entries grouped by strain (browse by keywords)

126 entries

Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus) reference strain

Select_allDeselect_all
VF439_IIV3 Probable kinase 098L (EC 2.7.-.-)
095L_IIV3 Probable matrix metalloproteinase 095L (EC 3.4.24.-)
TOP2_IIV3 DNA topoisomerase 2 (EC 5.6.2.2) (DNA topoisomerase II)
RIR1_IIV3 Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleotide reductase large ...
RIR2_IIV3 Probable ribonucleoside-diphosphate reductase small subunit 048L (EC 1.17.4.1) (Ribonucleotide ...
124R_IIV3 Uncharacterized protein 124R
VF184_IIV3 Putative helicase 121R (EC 3.6.4.-)
DPOL_IIV3 DNA polymerase 120R (EC 2.7.7.7)
VF414_IIV3 Putative hydrolase 111R (EC 3.6.1.-)
VF161_IIV3 Putative helicase 109L (EC 3.6.4.-)
VF355_IIV3 Putative CTD phosphatase-like protein 355R (EC 3.1.3.-)
RNC_IIV3 Putative ribonuclease 3 (EC 3.1.26.3)
VF347_IIV3 Putative FAD-linked sulfhydryl oxidase 096R (EC 1.8.3.2)
RPB1_IIV3 Probable DNA-directed RNA polymerase II subunit RPB1 homolog (EC 2.7.7.6)
VF022_IIV3 Putative helicase 087L (EC 3.6.4.-)
VF232_IIV3 Putative ubiquitin thioesterase 232R (EC 3.4.19.12)
080R_IIV3 Putative hydrolase 080R (EC 3.6.1.-)
VF244_IIV3 Putative phosphoesterase 078R (EC 3.1.-.-)
VF369_IIV3 Probable RAD2-like endonuclease 076L (EC 3.1.-.-)
VF197_IIV3 Putative tyrosine phosphatase 067L (EC 3.1.3.48)
VF349_IIV3 Putative transcription elongation factor S-II-like protein 055R
VF205_IIV3 Putative DNA ligase 052L (EC 6.5.1.2)
VF337_IIV3 Putative membrane protein 047R
044L_IIV3 Putative serine/threonine-protein kinase 040L (EC 2.7.11.-)
VF010_IIV3 Uncharacterized protein 043R
VF453_IIV3 Putative thioredoxin-like protein 041R
VF143_IIV3 Putative kinase protein 029R (EC 2.7.-.-)
VF224_IIV3 Probable cysteine proteinase 024R (EC 3.4.-.-)
VF193_IIV3 Putative apoptosis inhibitor 021L
MCP_IIV3 Major capsid protein (MCP)
VF380_IIV3 Probable serine/threonine-protein kinase 010L (EC 2.7.11.1)
RPB2_IIV3 Probable DNA-directed RNA polymerase II subunit RPB2 homolog (EC 2.7.7.6)
VF118_IIV3 Putative myristoylated protein 006R
VF067_IIV3 Uncharacterized protein 004R
126R_IIV3 Uncharacterized protein 126R
125R_IIV3 Uncharacterized protein 125R
123L_IIV3 Uncharacterized protein 123L
122R_IIV3 Uncharacterized protein 122R
119R_IIV3 Uncharacterized protein 119R
118R_IIV3 Uncharacterized protein 118R
117L_IIV3 Uncharacterized protein 117L
116R_IIV3 Uncharacterized protein 116R
VF342_IIV3 Uncharacterized protein 115R
114L_IIV3 Uncharacterized protein 114L
VF155_IIV3 Uncharacterized protein 113L
VF466_IIV3 Uncharacterized protein 112R
110R_IIV3 Uncharacterized protein 110R
108L_IIV3 Uncharacterized protein 108L
VF117_IIV3 Uncharacterized protein 107R
VF030_IIV3 Uncharacterized protein 106R
VF359_IIV3 Uncharacterized protein 105R
103L_IIV3 Uncharacterized protein 103L
102R_IIV3 Uncharacterized protein 102R
VF378_IIV3 Uncharacterized protein 100L
VF329_IIV3 Uncharacterized protein 099R
VF170_IIV3 Uncharacterized protein 97L
VF050_IIV3 Uncharacterized protein 094L
VF019_IIV3 Putative MSV199 domain-containing protein 093L
092R_IIV3 Uncharacterized protein 092R
VF396_IIV3 Uncharacterized protein 091L
089L_IIV3 Uncharacterized protein 089L
VF075_IIV3 Uncharacterized protein 088R
VF203_IIV3 Uncharacterized protein 085L
VF358_IIV3 Uncharacterized protein 083L
082L_IIV3 Uncharacterized protein 082L
081L_IIV3 Putative FAS1 domain-containing protein 081L
VF282_IIV3 Putative transcription factor 079L
077R_IIV3 Uncharacterized protein 077R
075R_IIV3 Uncharacterized protein 075R
VF268_IIV3 Uncharacterized protein 074L
073R_IIV3 Uncharacterized protein 073R
072L_IIV3 Uncharacterized protein 072L
VF259_IIV3 Uncharacterized protein 071L
VF306_IIV3 Putative SWIB domain-containing protein 070L
VF198_IIV3 Uncharacterized protein 069L
VF401_IIV3 High mobility group protein homolog 068R
VF357_IIV3 Transmembrane protein 066L
064L_IIV3 Uncharacterized protein 064L
VF309_IIV3 Uncharacterized protein 063R
062L_IIV3 Uncharacterized protein 062L
VF467_IIV3 Uncharacterized protein 061R
VF436_IIV3 Uncharacterized protein 060L
EX0N_IIV3 Putative exonuclease 059L (EC 3.1.11.-)
VF391_IIV3 Uncharacterized protein 058R
057L_IIV3 Uncharacterized protein 057L
VF287_IIV3 Uncharacterized protein 056L
054L_IIV3 Uncharacterized protein 054L
053L_IIV3 Uncharacterized protein 053L
VF213_IIV3 Uncharacterized protein 051L
VF145_IIV3 Uncharacterized protein 050L
049R_IIV3 Uncharacterized protein 049R
VF229_IIV3 Uncharacterized protein 229L
045R_IIV3 Uncharacterized protein 045R
VF136_IIV3 Uncharacterized protein 042R
040R_IIV3 Uncharacterized protein 040R
ICP46_IIV3 Immediate-early protein ICP-46 homolog
VF098_IIV3 Uncharacterized protein 038R
037L_IIV3 Uncharacterized protein 037L
VF219_IIV3 Uncharacterized protein 036R
VF179_IIV3 Uncharacterized protein 035R
VF077_IIV3 Putative zinc finger protein 034R
VF307_IIV3 Uncharacterized protein 033L
032R_IIV3 Uncharacterized protein 032R
VF115_IIV3 Uncharacterized protein 031R
030L_IIV3 uncharacterized protein 030L
028R_IIV3 Uncharacterized protein 028R
VF157_IIV3 Putative RING finger protein 027R
VF350_IIV3 Uncharacterized protein 026R
025R_IIV3 Uncharacterized protein 025R
023R_IIV3 Uncharacterized protein 023R
022L_IIV3 Transmembrane protein 022L
VF196_IIV3 Uncharacterized protein 020R
VF201_IIV3 Putative Bro-N domain-containing protein 019R
VF415_IIV3 Uncharacterized protein 018L
VF335_IIV3 Uncharacterized protein 017R
VF295_IIV3 Uncharacterized protein 016R
VF015_IIV3 Uncharacterized protein 015R
013L_IIV3 Uncharacterized protein IIV3-013L
VF302_IIV3 Putative zinc finger protein 012R
011L_IIV3 Uncharacterized protein 011L
008L_IIV3 Uncharacterized protein 008L
007R_IIV3 Uncharacterized protein 007R
005L_IIV3 Uncharacterized protein 005L
003L_IIV3 Uncharacterized protein 003L
002R_IIV3 Uncharacterized protein 002R
VF395_IIV3 Uncharacterized protein 001R

2 entries

Simulium iridescent virus (IIV-22) (Insect iridescent virus type 22)

Select_allDeselect_all
MCP_IRV22 Major capsid protein (MCP) (P50)
VF015_IRV22 Uncharacterized 15.9 kDa protein in MSP 5'region

1 entry

Wiseana iridescent virus (WIV) (Insect iridescent virus type 9)

MCP_IRV9 Major capsid protein (MCP) (P50)