Chloriridovirus

VIRION

Polyhedral virions 180 nm in diameter. The capsid displays an icosahedral symmetry T=189-217, with an internal lipid membrane. Virions are either externally enveloped or not depending whether they budded from the cell membrane, or were arranged in paracrystaline array in the host cell cytoplasm and were released by lysis.

GENOME

Linear, dsDNA genome of about 135 kb. The genome contains terminal and redundant sequences and is circularly permuted. Encodes for about 126 proteins. The genome is not methylated.

GENE EXPRESSION

REPLICATION

NUCLEO-CYTOPLASMIC

  1. Attachment of the viral proteins to host receptors mediates endocytosis of the virus into the host cell.
  2. Fusion with the plasma membrane to release the DNA core into the host cytoplasm.
  3. Viral DNA is transported to the cell nucleus where host macromolecular synthesis is rapidly shutdown. Transcription is initiated by virally modified host RNA polymerase II.
  4. Parental DNA is used to produce genome and greater than genome length DNA.
  5. Progeny DNA is transported into cytoplasmic viral factories where large concatamers of viral DNA are formed by recombination. Transcription of very late transcripts may also take place in the cytoplasm.
  6. Assembly of new virions in the cytoplasm.
  7. Virions exit the cell by budding or cell lysis.

Host-virus interaction

Apoptosis modulation

Invertebrate iridescent virus 3 encodes a protein homolog to the Chilo iridescent virus functional inhibitor of apoptosis (IAP) . This ORF may therefore play a role in the modulation of host apoptosis.

Matching UniProtKB/Swiss-Prot entries

126 entries grouped by strain (browse by keywords)

126 entries

Invertebrate iridescent virus 3 (IIV-3) (Mosquito iridescent virus) reference strain

Select_allDeselect_all
DPOL_IIV3 DNA polymerase 120R (EC 2.7.7.7)
EX0N_IIV3 Putative exonuclease 059L (EC 3.1.11.-)
RNC_IIV3 Putative ribonuclease 3 (EC 3.1.26.3)
RPB2_IIV3 Probable DNA-directed RNA polymerase II subunit RPB2 homolog (EC 2.7.7.6)
RPB1_IIV3 Probable DNA-directed RNA polymerase II subunit RPB1 homolog (EC 2.7.7.6)
ICP46_IIV3 Immediate-early protein ICP-46 homolog
TOP2_IIV3 DNA topoisomerase 2 (EC 5.99.1.3) (DNA topoisomerase II)
RIR1_IIV3 Ribonucleoside-diphosphate reductase large subunit (EC 1.17.4.1) (Ribonucleotide reductase large ...
RIR2_IIV3 Probable ribonucleoside-diphosphate reductase small subunit 048L (EC 1.17.4.1) (Ribonucleotide ...
MCP_IIV3 Major capsid protein (MCP)
VF022_IIV3 Putative helicase 087L (EC 3.6.4.-)
VF030_IIV3 Uncharacterized protein 106R
VF050_IIV3 Uncharacterized protein 094L
VF067_IIV3 Uncharacterized protein 004R
VF075_IIV3 Uncharacterized protein 088R
VF077_IIV3 Putative zinc finger protein 034R
VF098_IIV3 Uncharacterized protein 038R
VF115_IIV3 Uncharacterized protein 031R
VF118_IIV3 Putative myristoylated protein 006R
VF145_IIV3 Uncharacterized protein 050L
VF157_IIV3 Putative RING finger protein 027R
VF179_IIV3 Uncharacterized protein 035R
VF184_IIV3 Putative helicase 121R (EC 3.6.4.-)
VF193_IIV3 Putative apoptosis inhibitor 021L
VF196_IIV3 Uncharacterized protein 020R
VF198_IIV3 Uncharacterized protein 069L
VF201_IIV3 Putative Bro-N domain-containing protein 019R
VF203_IIV3 Uncharacterized protein 085L
VF213_IIV3 Uncharacterized protein 051L
VF224_IIV3 Probable cysteine proteinase 024R (EC 3.4.-.-)
VF244_IIV3 Putative phosphoesterase 078R (EC 3.1.-.-)
VF259_IIV3 Uncharacterized protein 071L
VF268_IIV3 Uncharacterized protein 074L
VF282_IIV3 Putative transcription factor 079L
VF306_IIV3 Putative SWIB domain-containing protein 070L
VF309_IIV3 Uncharacterized protein 063R
VF355_IIV3 Putative CTD phosphatase-like protein 355R (EC 3.1.3.-)
VF357_IIV3 Transmembrane protein 066L
VF369_IIV3 Probable RAD2-like endonuclease 076L (EC 3.1.-.-)
VF378_IIV3 Uncharacterized protein 100L
VF380_IIV3 Probable serine/threonine-protein kinase 010L (EC 2.7.11.1)
VF401_IIV3 High mobility group protein homolog 068R
VF436_IIV3 Uncharacterized protein 060L
VF466_IIV3 Uncharacterized protein 112R
VF010_IIV3 Uncharacterized protein 043R
VF015_IIV3 Uncharacterized protein 015R
VF019_IIV3 Putative MSV199 domain-containing protein 093L
VF117_IIV3 Uncharacterized protein 107R
VF136_IIV3 Uncharacterized protein 042R
VF143_IIV3 Putative kinase protein 029R (EC 2.7.-.-)
VF155_IIV3 Uncharacterized protein 113L
VF161_IIV3 Putative helicase 109L (EC 3.6.4.-)
VF170_IIV3 Uncharacterized protein 97L
VF197_IIV3 Putative tyrosine phosphatase 067L (EC 3.1.3.-)
VF205_IIV3 Putative DNA ligase 052L (EC 6.5.1.2)
VF219_IIV3 Uncharacterized protein 036R
VF229_IIV3 Uncharacterized protein 229L
VF232_IIV3 Putative ubiquitin thioesterase 232R (EC 3.4.19.12)
VF287_IIV3 Uncharacterized protein 056L
VF295_IIV3 Uncharacterized protein 016R
VF302_IIV3 Putative zinc finger protein 012R
VF307_IIV3 Uncharacterized protein 033L
VF329_IIV3 Uncharacterized protein 099R
VF335_IIV3 Uncharacterized protein 017R
VF337_IIV3 Putative membrane protein 047R
VF342_IIV3 Uncharacterized protein 115R
VF347_IIV3 Putative FAD-linked sulfhydryl oxidase 096R (EC 1.8.3.2)
VF349_IIV3 Putative transcription elongation factor S-II-like protein 055R
VF350_IIV3 Uncharacterized protein 026R
VF358_IIV3 Uncharacterized protein 083L
VF359_IIV3 Uncharacterized protein 105R
VF391_IIV3 Uncharacterized protein 058R
VF395_IIV3 Uncharacterized protein 001R
VF396_IIV3 Uncharacterized protein 091L
VF414_IIV3 Putative hydrolase 111R (EC 3.6.1.-)
VF415_IIV3 Uncharacterized protein 018L
VF439_IIV3 Probable kinase 098L (EC 2.7.-.-)
VF453_IIV3 Putative thioredoxin-like protein 041R
VF467_IIV3 Uncharacterized protein 061R
053L_IIV3 Uncharacterized protein 053L
103L_IIV3 Uncharacterized protein 103L
002R_IIV3 Uncharacterized protein 002R
092R_IIV3 Uncharacterized protein 092R
062L_IIV3 Uncharacterized protein 062L
126R_IIV3 Uncharacterized protein 126R
122R_IIV3 Uncharacterized protein 122R
095L_IIV3 Probable matrix metalloproteinase 095L (EC 3.4.24.-)
023R_IIV3 Uncharacterized protein 023R
119R_IIV3 Uncharacterized protein 119R
073R_IIV3 Uncharacterized protein 073R
089L_IIV3 Uncharacterized protein 089L
011L_IIV3 Uncharacterized protein 011L
037L_IIV3 Uncharacterized protein 037L
005L_IIV3 Uncharacterized protein 005L
123L_IIV3 Uncharacterized protein 123L
108L_IIV3 Uncharacterized protein 108L
057L_IIV3 Uncharacterized protein 057L
007R_IIV3 Uncharacterized protein 007R
013L_IIV3 Uncharacterized protein IIV3-013L
022L_IIV3 Transmembrane protein 022L
025R_IIV3 Uncharacterized protein 025R
110R_IIV3 Uncharacterized protein 110R
049R_IIV3 Uncharacterized protein 049R
030L_IIV3 uncharacterized protein 030L
081L_IIV3 Putative FAS1 domain-containing protein 081L
102R_IIV3 Uncharacterized protein 102R
117L_IIV3 Uncharacterized protein 117L
118R_IIV3 Uncharacterized protein 118R
008L_IIV3 Uncharacterized protein 008L
082L_IIV3 Uncharacterized protein 082L
072L_IIV3 Uncharacterized protein 072L
116R_IIV3 Uncharacterized protein 116R
077R_IIV3 Uncharacterized protein 077R
028R_IIV3 Uncharacterized protein 028R
114L_IIV3 Uncharacterized protein 114L
075R_IIV3 Uncharacterized protein 075R
124R_IIV3 Uncharacterized protein 124R
125R_IIV3 Uncharacterized protein 125R
032R_IIV3 Uncharacterized protein 032R
054L_IIV3 Uncharacterized protein 054L
003L_IIV3 Uncharacterized protein 003L
045R_IIV3 Uncharacterized protein 045R
040R_IIV3 Uncharacterized protein 040R
080R_IIV3 Putative hydrolase 080R (EC 3.6.1.-)
044L_IIV3 Putative serine/threonine-protein kinase 040L (EC 2.7.11.-)
064L_IIV3 Uncharacterized protein 064L