Gemycircularvirus (taxid:1542744)



Non-enveloped, round, T=1 icosahedral symmetry, about 20 nm in diameter.



Monopartite, circular, ssDNA genome genome of about 2.17 kb. There are coding regions in both the virion (positive) and complementary (negative) sense strands.
The replication (Rep) protein initiates and terminates rolling circle replication. Two intergenic regions separate the two ORFs, the large intergenic region (LIR, 133 nt) and the small intergenic region (SIR, 119 nt). There is a potential stem-loop structure in the LIR that includes a nona-nucleotide sequence (TAATATTAT) where ssDNA replication is initiated.
The short intergenic region contains bidirectional polyadenylation signals.


Transcription is bidirectional from the long intergenic region (LIR) which contains two divergent promoters. The resulting transcripts encode a capsid protein and a replication-associated protein.



  1. Virus attaches to host cell, and genomic DNA penetrates into the cytoplasm.
  2. Presumably the ssDNA is converted to dsDNA.
  3. Transcription of viral genes, possibly by a host RNA polymerase.
  4. Genome replication, possibly by rolling circle
  5. Assembly and release of virions.
These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna (ModelArchive).

Cassava associated gemycircularvirus 1 taxid:1985374

Protein ModelArchive
Capsid protein ma-jd-viral-28711
Replication-associated protein ma-jd-viral-17049

Common bean-associated gemycircularvirus taxid:1897538

Protein ModelArchive
Capsid protein ma-jd-viral-28682
RepA ma-jd-viral-17005
Replication-associated protein ma-jd-viral-20218

Dragonfly-associated circular virus 2 taxid:1234886

Protein ModelArchive
Putative coat protein ma-jd-viral-28726
Replication-associated protein ma-jd-viral-17019
Replication-associated protein ma-jd-viral-20141
Replication-associated protein ma-jd-viral-20403

Faeces associated gemycircularvirus 16 taxid:1843736

Protein ModelArchive
Capsid protein ma-jd-viral-28729
RepA ma-jd-viral-17024
Replication-associated protein ma-jd-viral-20247

Faeces associated gemycircularvirus 17 taxid:1843737

Protein ModelArchive
Capsid protein ma-jd-viral-28725
RepA ma-jd-viral-55596
Replication-associated protein ma-jd-viral-55597

Faeces associated gemycircularvirus 18 taxid:1843738

Protein ModelArchive
Capsid protein ma-jd-viral-28684
RepA ma-jd-viral-17027
Replication-associated protein ma-jd-viral-20527

Faeces associated gemycircularvirus 19 taxid:1843739

Protein ModelArchive
Capsid protein ma-jd-viral-28712
RepA ma-jd-viral-17046
Replication-associated protein ma-jd-viral-20629

Faeces associated gemycircularvirus 2 taxid:1391031

Protein ModelArchive
Capsid protein ma-jd-viral-28683
Replication associated protein ma-jd-viral-20287

Faeces associated gemycircularvirus 20 taxid:1843740

Protein ModelArchive
Capsid protein ma-jd-viral-28671
RepA ma-jd-viral-16993
Replication-associated protein ma-jd-viral-20353

Faeces associated gemycircularvirus 21 taxid:1843741

Protein ModelArchive
Capsid protein ma-jd-viral-28718
RepA ma-jd-viral-20174
Replication-associated protein ma-jd-viral-20352

Faeces associated gemycircularvirus 22 taxid:1843742

Protein ModelArchive
Capsid protein ma-jd-viral-28692
RepA ma-jd-viral-17022
Replication associated protein ma-jd-viral-17013

Faeces associated gemycircularvirus 4 taxid:1391033

Protein ModelArchive
Capsid protein ma-jd-viral-28677
Replication-associated protein ma-jd-viral-20559

Faeces associated gemycircularvirus 5 taxid:1391034

Protein ModelArchive
Capsid protein ma-jd-viral-28706
Replication-associated protein ma-jd-viral-20545

Faeces associated gemycircularvirus 6 taxid:1391035

Protein ModelArchive
Capsid protein ma-jd-viral-28737
Replication-associated protein ma-jd-viral-20476

Faeces associated gemycircularvirus 7 taxid:1391036

Protein ModelArchive
Capsid protein ma-jd-viral-28736
Replication associated protein ma-jd-viral-20235

Gemycircularvirus HV-GcV1 taxid:1862824

Protein ModelArchive
Capsid protein ma-jd-viral-28735
Replication initiation associated protein 1 ma-jd-viral-31880
Replication initiation associated protein 2 ma-jd-viral-20142
Uncharacterized protein ma-jd-viral-64870

Gemycircularvirus gemy-ch-rat1 taxid:1708653

Protein ModelArchive
Capsid protein ma-jd-viral-28663
Minor capsid protein ma-jd-viral-31882
Replication-associated protein ma-jd-viral-20241

Gerygone associated gemycircularvirus 3 taxid:1985383

Protein ModelArchive
Capsid protein ma-jd-viral-28694
Replication associated protein ma-jd-viral-20446

Mongoose feces-associated gemycircularvirus d taxid:1634487

Protein ModelArchive
Capsid ma-jd-viral-28707
Replication-associated protein ma-jd-viral-20455

Poecile atricapillus GI tract-associated gemycircularvirus taxid:1699094

Protein ModelArchive
Putative capsid protein ma-jd-viral-28685
Putative replication-associated protein ma-jd-viral-17006

Sclerotinia sclerotiorum hypovirulence associated DNA virus 1 taxid:664785

Protein ModelArchive
Coat protein ma-jd-viral-28669
Replication-associated protein ma-jd-viral-20285

Thrips-associated genomovirus 1 taxid:1941233

Protein ModelArchive
Capsid protein ma-jd-viral-28734
RepA ma-jd-viral-17010
Replication-associated protein ma-jd-viral-20372