Genomoviridae (taxid:1910928)

VIRION

Non-enveloped, round, T=1 icosahedral symmetry, about 20 nm in diameter.

GENOME

Monopartite, circular, ssDNA genome genome of about 2.17 kb. There are coding regions in both the virion (positive) and complementary (negative) sense strands.
The replication (Rep) protein initiates and terminates rolling circle replication. Two intergenic regions separate the two ORFs.
The short intergenic region contains bidirectional polyadenylation signals.

GENE EXPRESSION

Transcription is bidirectional from the long intergenic region (LIR) which contains two divergent promoters. The resulting transcripts encode a capsid protein and a replication-associated protein.

ENZYMES

Cress-type Endonuclease [Rep]

REPLICATION

Virus attaches to host cell, and genomic DNA penetrates into the cytoplasm.
Presumably the ssDNA is converted to dsDNA.
Transcription of viral genes, possibly by a host RNA polymerase.
Genome replication, possibly by rolling circle
Assembly and release of virions.

DB LINKS

TAXONOMY Group II: ssDNA viruses

Realm:	Monodnaviria
Kingdom:	Shotokuvirae
Phylum:	Cressdnaviricota
Class:	Repensiviricetes
Order:	Geplafuvirales
Family:	Genomoviridae
Genus:	Gemycircularvirus Gemyduguivirus Gemygorvirus Gemykibivirus Gemykolovirus Gemykrogvirus Gemykroznavirus Gemytondvirus Gemyvongvirus

ETYMOLOGY Gemycircular: for GEmini-like MYco-infecting CIRCULAR virus.

VIRUS

Bovine associated gemykrogvirus 1
Dragonfly associated gemyduguivirus 1
Dragonfly associated gemykibivirus 1
Human associated gemyvongvirus 1
Ostrich associated gemytondvirus 1
Pteropus associated gemykolovirus 1
Rabbit associated gemykroznavirus 1
Sclerotinia gemycircularvirus 1
Starling associated gemygorvirus 1
Badger associated gemykibivirus 1
Black robin associated gemykibivirus 1
Blackbird associated gemycircularvirus 1
Blackbird associated gemykibivirus 1
Bovine associated gemycircularvirus 1
Bovine associated gemykibivirus 1
Bromus associated gemycircularvirus 1
Canine associated gemygorvirus 1
Caribou associated gemykrogvirus 1
Cassava associated gemycircularvirus 1
Chickadee associated gemycircularvirus 1
Chicken associated gemycircularvirus 1
Chicken associated gemycircularvirus 2
Dragonfly associated gemycircularvirus 1
Equine associated gemycircularvirus 1
Fur seal associated gemycircularvirus 1
Gerygone associated gemycircularvirus 1
Gerygone associated gemycircularvirus 2
Gerygone associated gemycircularvirus 3
Human associated gemykibivirus 1
Human associated gemykibivirus 2
Human associated gemykibivirus 3
Human associated gemykibivirus 4
Human associated gemykibivirus 5
Hypericum associated gemycircularvirus 1
Lama associated gemycircularvirus 1
Mallard associated gemycircularvirus 1
Mallard associated gemygorvirus 1
Miniopterus associated gemycircularvirus 1
Mongoose associated gemycircularvirus 1
Mongoose associated gemykibivirus 1
Mosquito associated gemycircularvirus 1
Odonata associated gemycircularvirus 1
Odonata associated gemycircularvirus 2
Poaceae associated gemycircularvirus 1
Porcine associated gemycircularvirus 1
Porcine associated gemycircularvirus 2
Pteropus associated gemycircularvirus 1
Pteropus associated gemycircularvirus 10
Pteropus associated gemycircularvirus 2
Pteropus associated gemycircularvirus 3
Pteropus associated gemycircularvirus 4
Pteropus associated gemycircularvirus 5
Pteropus associated gemycircularvirus 6
Pteropus associated gemycircularvirus 7
Pteropus associated gemycircularvirus 8
Pteropus associated gemycircularvirus 9
Pteropus associated gemygorvirus 1
Pteropus associated gemykibivirus 1
Pteropus associated gemykolovirus 2
Rat associated gemycircularvirus 1
Rhinolophus associated gemykibivirus 1
Rhinolophus associated gemykibivirus 2
Sewage derived gemycircularvirus 1
Sewage derived gemycircularvirus 2
Sewage derived gemycircularvirus 3
Sewage derived gemycircularvirus 4
Sewage derived gemycircularvirus 5
Sewage derived gemygorvirus 1
Sewage derived gemykibivirus 1
Sewage derived gemykibivirus 2
Sewage derived gemykrogvirus 1
Sheep associated gemycircularvirus 1
Soybean associated gemycircularvirus 1

Host

NATURAL HOSTS Human, mammals, birds and fungi

TROPISM

INTERACTIONS Cell receptors: -
Host-virus interaction

Ecology and disease

GEOGRAPHY

ASSOCIATED DISEASES

TRANSMISSION

VACCINE

ANTIVIRAL DRUGS

These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna

(ModelArchive).

Badger associated gemykibivirus 1 taxid:1634484

Protein	ModelArchive
Capsid	ma-jd-viral-28699
Rep	ma-jd-viral-20578

Black robin associated gemykibivirus 1 taxid:1391037

Protein	ModelArchive
Capsid protein	ma-jd-viral-28668
Replication-associated protein	ma-jd-viral-20292

Blackbird associated gemykibivirus 1 taxid:1391038

Protein	ModelArchive
Capsid protein	ma-jd-viral-28704
Replication-associated protein	ma-jd-viral-20297

Cassava associated gemycircularvirus 1 taxid:1985374

Protein	ModelArchive
Capsid protein	ma-jd-viral-28711
Replication-associated protein	ma-jd-viral-17049

Chicken stool-associated gemycircularvirus taxid:1930298

Protein	ModelArchive
Capsid protein	ma-jd-viral-28710
Replication associated protein	ma-jd-viral-16985

Common bean-associated gemycircularvirus taxid:1897538

Protein	ModelArchive
Capsid protein	ma-jd-viral-28682
RepA	ma-jd-viral-17005
Replication-associated protein	ma-jd-viral-20218

Dragonfly associated gemykibivirus 1 taxid:1234887

Protein	ModelArchive
Putative coat protein	ma-jd-viral-28700
Replication-associated protein	ma-jd-viral-16989
Replication-associated protein	ma-jd-viral-20144
Spliced replication-associated protein	ma-jd-viral-17017

Dragonfly-associated circular virus 2 taxid:1234886

Protein	ModelArchive
Putative coat protein	ma-jd-viral-28726
Replication-associated protein	ma-jd-viral-17019
Replication-associated protein	ma-jd-viral-20141
Replication-associated protein	ma-jd-viral-20403

Dragonfly-associated circular virus 3 taxid:1234884

Protein	ModelArchive
Putative coat protein	ma-jd-viral-28717
Replication-associated protein	ma-jd-viral-17053
Replication-associated protein	ma-jd-viral-17001
Replication-associated protein	ma-jd-viral-20143

Faeces associated gemycircularvirus 10 taxid:1391025

Protein	ModelArchive
Capsid protein	ma-jd-viral-28720
Replication-associated protein	ma-jd-viral-20392

Faeces associated gemycircularvirus 11 taxid:1391026

Protein	ModelArchive
Capsid protein	ma-jd-viral-27776
Replication associated protein	ma-jd-viral-20260

Faeces associated gemycircularvirus 12 taxid:1391027

Protein	ModelArchive
Capsid protein	ma-jd-viral-27475
Replication associated protein	ma-jd-viral-20175

Faeces associated gemycircularvirus 14 taxid:1843734

Protein	ModelArchive
Capsid protein	ma-jd-viral-28667
RepA	ma-jd-viral-17040
Replication-associated protein	ma-jd-viral-17036

Faeces associated gemycircularvirus 15 taxid:1843735

Protein	ModelArchive
Capsid protein	ma-jd-viral-28715
RepA	ma-jd-viral-17047
Replication-associated protein	ma-jd-viral-16994

Faeces associated gemycircularvirus 16 taxid:1843736

Protein	ModelArchive
Capsid protein	ma-jd-viral-28729
RepA	ma-jd-viral-17024
Replication-associated protein	ma-jd-viral-20247

Faeces associated gemycircularvirus 17 taxid:1843737

Protein	ModelArchive
Capsid protein	ma-jd-viral-28725
RepA	ma-jd-viral-55596
Replication-associated protein	ma-jd-viral-55597

Faeces associated gemycircularvirus 18 taxid:1843738

Protein	ModelArchive
Capsid protein	ma-jd-viral-28684
RepA	ma-jd-viral-17027
Replication-associated protein	ma-jd-viral-20527

Faeces associated gemycircularvirus 19 taxid:1843739

Protein	ModelArchive
Capsid protein	ma-jd-viral-28712
RepA	ma-jd-viral-17046
Replication-associated protein	ma-jd-viral-20629

Faeces associated gemycircularvirus 2 taxid:1391031

Protein	ModelArchive
Capsid protein	ma-jd-viral-28683
Replication associated protein	ma-jd-viral-20287

Faeces associated gemycircularvirus 20 taxid:1843740

Protein	ModelArchive
Capsid protein	ma-jd-viral-28671
RepA	ma-jd-viral-16993
Replication-associated protein	ma-jd-viral-20353

Faeces associated gemycircularvirus 21 taxid:1843741

Protein	ModelArchive
Capsid protein	ma-jd-viral-28718
RepA	ma-jd-viral-20174
Replication-associated protein	ma-jd-viral-20352

Faeces associated gemycircularvirus 22 taxid:1843742

Protein	ModelArchive
Capsid protein	ma-jd-viral-28692
RepA	ma-jd-viral-17022
Replication associated protein	ma-jd-viral-17013

Faeces associated gemycircularvirus 4 taxid:1391033

Protein	ModelArchive
Capsid protein	ma-jd-viral-28677
Replication-associated protein	ma-jd-viral-20559

Faeces associated gemycircularvirus 5 taxid:1391034

Protein	ModelArchive
Capsid protein	ma-jd-viral-28706
Replication-associated protein	ma-jd-viral-20545

Faeces associated gemycircularvirus 6 taxid:1391035

Protein	ModelArchive
Capsid protein	ma-jd-viral-28737
Replication-associated protein	ma-jd-viral-20476

Faeces associated gemycircularvirus 7 taxid:1391036

Protein	ModelArchive
Capsid protein	ma-jd-viral-28736
Replication associated protein	ma-jd-viral-20235

Gemycircularvirus HV-GcV1 taxid:1862824

Protein	ModelArchive
Capsid protein	ma-jd-viral-28735
Replication initiation associated protein 1	ma-jd-viral-31880
Replication initiation associated protein 2	ma-jd-viral-20142
Uncharacterized protein	ma-jd-viral-64870

Gemycircularvirus HV-GcV2 taxid:1862825

Protein	ModelArchive
Capsid protein	ma-jd-viral-28713
Replication initiation associated protein	ma-jd-viral-20249
Uncharacterized protein	ma-jd-viral-33825

Gemycircularvirus gemy-ch-rat1 taxid:1708653

Protein	ModelArchive
Capsid protein	ma-jd-viral-28663
Minor capsid protein	ma-jd-viral-31882
Replication-associated protein	ma-jd-viral-20241

Gerygone associated gemycircularvirus 3 taxid:1985383

Protein	ModelArchive
Capsid protein	ma-jd-viral-28694
Replication associated protein	ma-jd-viral-20446

Human genital-associated circular DNA virus-1 taxid:1488574

Protein	ModelArchive
Capsid protein	ma-jd-viral-28727
RepA	ma-jd-viral-17032
Replication-associated protein	ma-jd-viral-20306

Human plasma-associated gemycircularvirus taxid:1707330

Protein	ModelArchive
Capsid protein	ma-jd-viral-28702
Putative ORF3 protein	ma-jd-viral-43129
Replication-associated protein	ma-jd-viral-20382

Mongoose feces-associated gemycircularvirus a taxid:1634485

Protein	ModelArchive
Capsid	ma-jd-viral-28658
Rep	ma-jd-viral-16984

Mongoose feces-associated gemycircularvirus b taxid:1634486

Protein	ModelArchive
Capsid	ma-jd-viral-28733
Rep	ma-jd-viral-20478

Mongoose feces-associated gemycircularvirus c taxid:1634488

Protein	ModelArchive
Capsid	ma-jd-viral-28666
Replication-associated protein	ma-jd-viral-20454

Mongoose feces-associated gemycircularvirus d taxid:1634487

Protein	ModelArchive
Capsid	ma-jd-viral-28707
Replication-associated protein	ma-jd-viral-20455

Poecile atricapillus GI tract-associated gemycircularvirus taxid:1699094

Protein	ModelArchive
Putative capsid protein	ma-jd-viral-28685
Putative replication-associated protein	ma-jd-viral-17006

Sclerotinia sclerotiorum hypovirulence associated DNA virus 1 taxid:664785

Protein	ModelArchive
Coat protein	ma-jd-viral-28669
Replication-associated protein	ma-jd-viral-20285

Sewage associated gemycircularvirus 3 taxid:1843761

Protein	ModelArchive
Capsid protein	ma-jd-viral-28680
RepA	ma-jd-viral-17012
Replication-associated protein	ma-jd-viral-17034

Thrips-associated genomovirus 1 taxid:1941233

Protein	ModelArchive
Capsid protein	ma-jd-viral-28734
RepA	ma-jd-viral-17010
Replication-associated protein	ma-jd-viral-20372

Thrips-associated genomovirus 2 taxid:1941234

Protein	ModelArchive
Capsid protein	ma-jd-viral-28691
RepA	ma-jd-viral-17045
Replication-associated protein	ma-jd-viral-16987

Thrips-associated genomovirus 3 taxid:1941237

Protein	ModelArchive
Capsid protein	ma-jd-viral-28708
RepA	ma-jd-viral-17033
Replication-associated protein	ma-jd-viral-17016

Thrips-associated genomovirus 4 taxid:1941239

Protein	ModelArchive
Capsid protein	ma-jd-viral-28701
RepA	ma-jd-viral-17052
Replication-associated protein	ma-jd-viral-20370