Dendritic cells are key determinants of viral disease outcome since they are able to trigger immune responses during viral infection. Several viruses prevent cytokine production by dendritic cells in order to facilitate release of progeny. Viruses can interfere at several steps of Denritic cells induced immunity including generation, survival, migration and maturation, as well as processing/presentation of antigen by DCs.
Table. Viruses modulating the activity of dendritic cells.
| Virus | Family | Viral protein | References |
| Measles virus | Paramyxoviridae, Morbillivirus | protein V |  |
| HCV | Flaviviridae, Hepacivirus | Core protein | |
| HTLV-1 | Retroviridae, Deltaretrovirus | Tax | |
| HIV | Retroviridae, Lentivirus | Vpu | |
| Influenza A | Orthomyxoviridae, Influenzavirus A | NS1 | |
| HHV-1 | Herpesviridae, Simplexvirus | ICP34.5 | |
| Ebola virus | Filoviridae, Ebola-like viruses | VP35 | |
Modulation of the Immune System by Human Rhinoviruses Int Arch Allergy Immunol 2007;142:1-10 by DC and activation of T-cell responses by DC
Table. Viruses infecting host dendritic cells.
| Virus | Family | References | |
| Porcine respiratory and reproductive syndrome virus | Arteriviridae, Arterivirus | |
|
| Herpes simplex virus | Herpesviridae, Simplexvirus | |
|
| HIV1 | Retroviridae, Lentivirus | |
|
| HIV | Retroviridae, Lentivirus | |
|
| Influenza A | Orthomyxoviridae, Influenzavirus A | NS1 | |
| HHV-1 | Herpesviridae, Simplexvirus | ICP34.5 | |
| Ebola virus | Filoviridae, Ebola-like viruses | VP35 | |