SARS-Cov-2 resource ~ ViralZone

ViralZone

ViralZone resources

Betacoronavirus fact sheet	Genome and expression	Variants
Coronavirus life cycle	Proteome	Interactome
COVID-19 and treatment	Vaccines	Antiviral drugs

External resources:

COVID-19 UniProt resource	Cellosaurus Cell culture for SARS-Cov-2	Nextstrain Genomic epidemiology of SARSCoV2
SIB SARS-CoV-2 resources	NCBI SARS-CoV-2	Elixir SARS-CoV-2
PDB structures	Worldmeter of COVID-19 infections/deaths	Medical data on COVID-19
	Coronaviruses 101: Focus on Molecular Virology by Britt Glaunsinger, University of California

DB LINKS Nucleotide DB: NCBI
Protein DB: UniProtKB

Virus DB:

TAXONOMY Group IV: ssRNA positive-strand viruses

Order:	Nidovirales
Family:	Coronaviridae
Subfamily:	Coronavirinae
Genus:	Betacoronavirus

ETYMOLOGY Coronavirus: from latin corona (crown), referring to the shape of proteins around the virion

VIRUS

REFERENCE STRAINS SARS-CoV-2
Sequence | UCSC genome | Proteome

Host

NATURAL HOSTS Human. Occasional: Mink, great apes (gorrilla,.), Feline (cats,lion, tigers,.), dogs, bats, pangolin.

TROPISM Primary site of infection: epithelial cells of respiratory or enteric tracts. secondary: Central Nervous System, kidney, heart tissues?

INTERACTIONS Cell receptors:

SARS-CoV-2: ACE2

Ecology and disease

GEOGRAPHY Worldwide, Emerged in China.

ASSOCIATED DISEASES COVID-19: Mainly respiratory diseases (pneumonia), with cardiac complications.

TRANSMISSION Respiratory droplets, fomites.

VACCINE

ANTIVIRAL DRUGS Remdesivir (Experimental, viral polymerase inhibitor)