Skip to main content
ViralZone logo emblem ViralZone

Viral penetration via lysis of host organellar membrane (kw:KW-1174)

image

Non-enveloped viruses transfer their genetic material from endosome compartment to cell cytoplasm through membrane permeabilization or lysis.
Lysis occurs when a viral capsid induces rupture of endosomal membrane. This process occurs after capsid protein conformational change triggered by endosomal acidic pH or upon receptor binding. The result is either viral particle escape to the cytoplasm (Adenovirus 2 and 5) or release of viral genome into the cytoplasm (Human rhinovirus)

Viral molecular biology Virion
Virus entry
Virus latency
Transcription and replication
Host-virus interactions
Virus exit
Links Uniprot Keyword: KW-1174
GO ontology:GO:0039664
Virus Adenoviridae, Mastadenovirus
Ad2, Ad5, Ad7

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

11 entries grouped by strain

1 entry

Fowl adenovirus A serotype 1 (strain CELO / Phelps) (FAdV-1) (Avian adenovirus gal1 (strain Phelps)) reference strain

CAP6_ADEG1 Pre-protein VI (pVI) [Cleaved into: Endosome lysis protein; Protease cofactor (pVI-C)]

1 entry

Human adenovirus A serotype 12 (HAdV-12) (Human adenovirus 12) reference strain

CAP6_ADE12 Pre-protein VI (pVI) [Cleaved into: Endosome lysis protein; Protease cofactor (pVI-C)]

1 entry

Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2) reference strain

CAP6_ADE02 Pre-protein VI (pVI) [Cleaved into: Endosome lysis protein; Protease cofactor (pVI-C)]

pdb 1AVP; 1NLN; 4PID; 4PIE; 5FGY

1 entry

Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) reference strain

CAP6_ADE05 Pre-protein VI (pVI) [Cleaved into: Endosome lysis protein; Protease cofactor (pVI-C)]

pdb 6CGV; 7S78

1 entry

Human adenovirus F serotype 40 (HAdV-40) (Human adenovirus 40) reference strain

CAP6_ADE40 Pre-protein VI (pVI) [Cleaved into: Endosome lysis protein; Protease cofactor (pVI-C)]

1 entry

Snake adenovirus serotype 1 (SnAdV-1) reference strain

CAP6_ADES1 Pre-protein VI (pVI) [Cleaved into: Endosome lysis protein; Protease cofactor (pVI-C)]

1 entry

Canine adenovirus serotype 1 (strain CLL) (CAdV-1) (Canine adenovirus 1 (strain CLL))

CAP6_ADECC Pre-protein VI (pVI) [Cleaved into: Endosome lysis protein; Protease cofactor (pVI-C)]

1 entry

Canine adenovirus serotype 1 (strain RI261) (CAdV-1) (Canine adenovirus 1 (strain RI261))

CAP6_ADECR Pre-protein VI (pVI) [Cleaved into: Endosome lysis protein; Protease cofactor (pVI-C)]

1 entry

Human adenovirus F serotype 41 (HAdV-41) (Human adenovirus 41)

CAP6_ADE41 Pre-protein VI (pVI) [Cleaved into: Endosome lysis protein; Protease cofactor (pVI-C)]

pdb 6YBA; 6Z7N

1 entry

Human rhinovirus 14 (HRV-14)

POLG_HRV14 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion ...

pdb 1D3I; 1HRI; 1HRV; 1K5M; 1NA1; 1NCQ; 1R08; 1R09; 1RMU; 1RUC; 1RUD; 1RUE; 1RUF; 1RUG; 1RUH; 1RUI; 1RUJ; 1RVF; 1VRH; 1XR5; 2B0F; 2HWB; 2HWC; 2IN2; 2R04; 2R06; 2R07; 2RM2; 2RMU; 2RR1; 2RS1; 2RS3; 2RS5; 4PDW; 4RHV; 5W3E; 5W3L; 5W3M; 5W3O; 6HLT; 6KYZ; 6KZ0

1 entry

Murine adenovirus A serotype 1 (MAdV-1) (Murine adenovirus 1)

CAP6_ADEM1 Pre-protein VI (pVI) [Cleaved into: Endosome lysis protein; Protease cofactor (pVI-C)]