Viral tail assembly (kw:KW-1245)

Siphoviridae and Myoviridae tail and head assemblies occur independently. Tail assembly follows a sequential order . The tail measure protein (or tape measure protein, ruler) determines the length of Sipho- and Myoviridae tails .

image

Tail tube protein polymerization starts from baseplate assembly. The tail measure protein possibly assembles with tail assembly chaperones, and the resulting complex interacts with baseplate to form the tail initiator. Tail tube protein polymerizes on this template and displaces the chaperones thereby creating the tube. It is unclear whether the tail measure protein is trapped inside.Once polymerization of the cylindrical part(s) of the tail has reached the expected length, terminator proteins stop the polymerization . In the phage lambda, the TMP is matured.

In many viruses, the tail assembly gene is expressed through a programmed translational frameshift and gives rise to two chaperone proteins with overlapping sequences .

Viral molecular biology Virion
Virus entry
Virus latency
Transcription and replication
Host-virus interactions
Virus exit
Links Uniprot Keyword:KW-1245
GO ontology:GO:0098003
Virus Myoviridae
Siphoviridae

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

90 entries grouped by protein

1 entry

Baseplate wedge protein gp6 (Gene product 6) (gp6)

BP06_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

pdb 3H2T; 3H3W; 3H3Y; 5HX2; 5IV5; 5IV7

1 entry

Baseplate wedge protein gp7 (Gene product 7) (gp7)

BP07_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

pdb 5HX2; 5IV5; 5IV7

1 entry

Baseplate wedge protein gp8 (Gene product 8) (gp8)

BP08_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

pdb 1N7Z; 1N80; 1N8B; 1PDM; 1TJA; 5HX2; 5IV5; 5IV7

1 entry

Baseplate protein gp9 (Gene product 9) (gp9)

BP09_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

pdb 1PDP; 1QEX; 1S2E; 1TJA; 1ZKU; 5IV5; 5IV7

1 entry

Baseplate wedge protein gp10 (Gene product 10) (gp10)

BP10_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

pdb 2FKK; 2FL8; 2FL9; 5HX2; 5IV5; 5IV7

1 entry

Baseplate wedge protein gp11 (Gene product 11) (gp11)

BP11_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

pdb 1EL6; 1PDF; 1TJA; 5IV5; 5IV7

1 entry

Baseplate central spike complex protein gp27 (Gene product 27) (gp27) (Hub protein 27)

BP27_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

pdb 1K28; 1PDJ; 1WTH; 2Z6B; 5IV5

1 entry

Baseplate hub protein gp44 (43 kDa tail protein) (Gene product 44) (gp44) (Gene product P) (gpP)

BP44_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain

pdb 1WRU

1 entry

Baseplate puncturing device gp45 (Baseplate spike protein) (Gene product 45) (gp45) (Gene product Q) (gpQ)

BP45_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain

pdb 3VTN; 3VTO

1 entry

Baseplate protein gp46 (Gene product 46) (gp46) (Gene product V) (gpV)

BP46_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain

1 entry

Baseplate protein gp47 (Gene product 47) (gp47) (Gene product W) (gpW)

BP47_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain

2 entries

Baseplate protein gp48 (Gene product 48) (gp48) (Gene product R) (gpR)

Select_allDeselect_all
BP48_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain
BP48_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

Baseplate tail-tube junction protein gp48 (Baseplate-tube cap) (Gene product 48) (gp48)

pdb 5IV5

1 entry

Baseplate wedge protein gp53 (Gene product 53) (gp53)

BP53_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

pdb 5HX2; 5IV5; 5IV7

1 entry

Baseplate tail-tube junction protein gp54 (Gene product 54) (gp54)

BP54_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

pdb 5IV5

1 entry

Baseplate protein I (Gene I protein) (GpI)

BPI_BPP2
Escherichia phage P2 (Bacteriophage P2) reference strain

1 entry

Baseplate protein W (Gene W protein) (GpW)

BPW_BPP2
Escherichia phage P2 (Bacteriophage P2) reference strain

1 entry

DNA circularization protein N (64 kDa virion protein) (Gene product 43) (gp43) (Gene product N) (gpN)

CIRCN_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain

2 entries

Tail completion protein gp17 (Gene product 17) (gp17) (Head-tail joining protein gp17) (Tail-to-head joining protein)

Select_allDeselect_all
COMPL_BPSPP
Bacillus phage SPP1 (Bacteriophage SPP1) reference strain

pdb 2LFP; 5A20; 5A21

COMPL_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

Tail completion protein p143 (Tail protein p143)

2 entries

Tail assembly protein G (Gene product 14) (gp14) (Gene product G) (gpG) (Minor tail protein G) (Tail assembly chaperone) (TAC)

Select_allDeselect_all
G_BPN15
Escherichia phage N15 (Bacteriophage N15) reference strain
G_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

Tail assembly protein G (Gene product G) (gpG) (Minor tail protein G) (Tail assembly chaperone) (TAC)

2 entries

Chaperone protein gp12 (Gene product 12) (gp12)

Select_allDeselect_all
GP12_BPLSK
Lactococcus phage SK1 (Lactococcus lactis bacteriophage SK1) reference strain

Chaperone protein gp12 (Gene product 12) (gp12) (Probable chaperone protein gp12)

GP12_BPLP2
Lactococcus phage p2 (Lactococcus lactis bacteriophage p2)

pdb 3D8L

2 entries

Morphogenesis protein 1 (Gene product 13) (gp13) (Protein p13)

Select_allDeselect_all
GP13_BPPH2
Bacillus phage phi29 (Bacteriophage phi-29) reference strain

pdb 3CSQ; 3CSR; 3CSZ; 3CT0; 3CT1; 3CT5

GP13_BPPZA
Bacillus phage PZA (Bacteriophage PZA)

1 entry

Baseplate hub assembly protein gp26 (Gene product 26) (gp26) (Hub protein 26)

GP26_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

1 entry

Baseplate hub assembly protein gp28 (Gene product 28) (gp28)

GP28_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

1 entry

Putative sheath terminator protein (Gene product 38) (gp38)

GP38_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain

1 entry

Tail fiber assembly helper protein (Gene product 57) (gp57)

GP57_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

2 entries

Protein 7.3 (Gene product 7.3) (Gp7.3)

Select_allDeselect_all
GP73_BPT7
Escherichia phage T7 (Bacteriophage T7) reference strain
GP73_BPT3
Enterobacteria phage T3 (Bacteriophage T3)

Protein 7.3 (Gene product 7.3) (Gp7.3) (Host specificity protein B)

2 entries

Tail assembly protein GT (Gene product 15) (gp15) (Gene product GT) (gpGT) (Minor tail protein GT)

Select_allDeselect_all
GT_BPN15
Escherichia phage N15 (Bacteriophage N15) reference strain
GT_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

2 entries

Pre-baseplate central spike protein Gp5 (Pre-Gp5) (Peptidoglycan hydrolase gp5) (EC 3.2.1.17)

Select_allDeselect_all
NEEDL_BPKVM
Vibrio phage KVP40 (isolate Vibrio parahaemolyticus/Japan/Matsuzaki/1991) (KVP40) (Bacteriophage KVP40) reference strain

Protein Gp5

NEEDL_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

pdb 1K28; 1PDL; 1WTH; 2Z6B; 3A1M; 4JIV; 4JIW; 4JJ2; 4KU0; 4OSD; 5IV5; 6P1Z; 6P20; 6P22; 6P2A; 6XC0; 6XC1; 7CN7

1 entry

Spike protein (Baseplate assembly protein gpV) (Gene V protein) (GpV)

SPIKE_BPP2
Escherichia phage P2 (Bacteriophage P2) reference strain

pdb 3AQJ; 3QR7; 3QR8; 8VOL; 8VOM; 8VON

2 entries

Probable tail assembly protein gp41 (Gene product 41) (gp41) (Tail assembly chaperone)

Select_allDeselect_all
TAP_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain
TAP_BPP2
Escherichia phage P2 (Bacteriophage P2) reference strain

Tail assembly protein E (Gene product E) (gpE) (Tail assembly chaperone) (TAC)

2 entries

Tail assembly protein Gp25 (Gene 25 protein) (Gp25)

Select_allDeselect_all
TAP25_BPMD2
Mycobacterium phage D29 (Mycobacteriophage D29) reference strain
TAP25_BPML5
Mycobacterium phage L5 (Mycobacteriophage L5) reference strain

1 entry

Baseplate hub assembly protein gp51 (Gene product 51) (gp51) (Hub assembly chaperone gp51) (Tail assembly protein gp51)

TAP51_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

2 entries

Probable tail assembly protein FS-gp41

Select_allDeselect_all
TAPFS_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain
TAPFS_BPP2
Escherichia phage P2 (Bacteriophage P2) reference strain

Tail assembly protein E' (Gene product E') (gpE') (Tail assembly chaperone) (TAC)

5 entries

Probable tail fiber assembly protein (P37)

Select_allDeselect_all
TFA_BPAPS
Acyrthosiphon pisum secondary endosymbiont phage 1 (Bacteriophage APSE-1) reference strain
TFA_BPP2
Escherichia phage P2 (Bacteriophage P2) reference strain

Probable tail fiber assembly protein (GpG)

TFA_BPSF5
Shigella phage SfV (Shigella flexneri bacteriophage V) (Bacteriophage SfV) reference strain
TFA_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

Tail fiber assembly protein (Gene product 38) (gp38) (Receptor recognizing protein)

TFA_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

Tail fiber assembly protein

2 entries

Tail tip assembly protein I

Select_allDeselect_all
TIPI_BPN15
Escherichia phage N15 (Bacteriophage N15) reference strain

Tail tip assembly protein I (Gene product 20) (gp20)

TIPI_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

pdb 8IYK; 8IYL; 8K35; 8XCG

1 entry

Tip attachment protein J (Central tail fiber) (Host specificity protein J)

TIPJ_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

pdb 8IYK; 8IYL; 8JVM; 8K35; 8XCG; 8XCI; 8XCJ; 8XCK

2 entries

Tail tip assembly protein K (Gene product 19) (gp19) (Probable endopeptidase) (EC 3.4.-.-) (Tail assembly protein K)

Select_allDeselect_all
TIPK_BPN15
Escherichia phage N15 (Bacteriophage N15) reference strain
TIPK_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

Tail tip assembly protein K (Probable endopeptidase) (EC 3.4.-.-) (Tail assembly protein K)

2 entries

Tail tip protein L

Select_allDeselect_all
TIPL_BPN15
Escherichia phage N15 (Bacteriophage N15) reference strain

Tail tip protein L (Gene product 18) (gp18)

TIPL_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

pdb 8IYK; 8IYL; 8K35; 8XCG

1 entry

Tail tip protein M

TIPM_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

pdb 8IYK; 8IYL; 8K35; 8XCG

20 entries

Probable tape measure protein (TMP)

Select_allDeselect_all
TMP_BPBMU
Burkholderia phage BcepMu (isolate -/United States/Summer/2002) (Bacteriophage BcepMu) reference strain

Probable tape measure protein (TMP) (Gene product 44) (gp44)

TMP_BPDP1
Pneumococcus phage Dp-1 (Bacteriophage Dp-1) reference strain

Tape measure protein (TMP)

TMP_BPFO1
Salmonella phage Felix O1 (isolate Felix O1-VT1) (Bacteriophage Felix O1) reference strain
TMP_BPHA1
Halomonas phage phiHAP-1 (isolate -/Gulf of Mexico/-/2001) (Bacteriophage phiHAP-1) reference strain

Probable tape measure protein (TMP) (Gene product 23) (gp23)

TMP_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

Probable tape measure protein (TMP) (Gene product 27) (gp27)

TMP_BPLC2
Lactococcus phage c2 reference strain

Probable tape measure protein (TMP) (Gene product 110) (gp110)

TMP_BPLSK
Lactococcus phage SK1 (Lactococcus lactis bacteriophage SK1) reference strain

Probable tape measure protein (TMP) (Gene product 14) (gp14)

TMP_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain

Probable tape measure protein (TMP) (Gene product 42) (gp42) (Gene product Y) (gpY)

TMP_BPN15
Escherichia phage N15 (Bacteriophage N15) reference strain

Tape measure protein (TMP) (Gene product 16) (gp16)

TMP_BPP2
Escherichia phage P2 (Bacteriophage P2) reference strain

Probable tape measure protein (TMP) (Gene product T) (gpT)

TMP_BPPAJ
Pseudomonas phage PAJU2 reference strain

Tape measure protein (TMP) (ORF10 protein) (Structural protein 1)

TMP_BPPCD
Clostridium phage phiCD119 (strain Clostridium difficile/United States/Govind/2006) (Bacteriophage phiCD119) reference strain
TMP_BPPHC
Streptomyces phage phiC31 (Bacteriophage phi-C31) reference strain

Probable tape measure protein (TMP) (Gene product 43) (gp43)

TMP_BPSPB
Bacillus phage SPbeta (Bacillus phage SPBc2) (Bacteriophage SP-beta) reference strain

Probable tape measure protein (TMP) (Transglycosylase) (EC 4.2.2.n1)

TMP_BPSPP
Bacillus phage SPP1 (Bacteriophage SPP1) reference strain

Tail tape measure protein gp18 (Gene product 18) (gp18)

TMP_BPT1
Escherichia phage T1 (Bacteriophage T1) reference strain

Tape measure protein (TMP) (Gene product 38) (gp38)

TMP_BPT4
Enterobacteria phage T4 (Bacteriophage T4) reference strain

Tape measure protein (TMP) (Gene product 29) (gp29) (Tail length regulator)

TMP_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

Tape measure protein pb2 precursor (TMP-pb2) (Pore-forming protein pb2) (Tail protein pb2)

pdb 7ZHJ; 7ZN2; 7ZQB; 7ZQP

TMP_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

Tape measure protein (TMP) (Gene product H) (gpH) (Minor tail protein H)

pdb 8IYK; 8IYL; 8K35

TMP_BPLP2
Lactococcus phage p2 (Lactococcus lactis bacteriophage p2)

Probable tape measure protein (TMP) (Gene product 14) (gp14)

1 entry

Probable tail terminator protein (TrP) (Gene product 37) (gp37) (Gene product K) (gpK)

TRP_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain

5 entries

Probable tail terminator protein (Gene product 10) (gp10)

Select_allDeselect_all
TTTP_BPLSK
Lactococcus phage SK1 (Lactococcus lactis bacteriophage SK1) reference strain
TTTP_BPN15
Escherichia phage N15 (Bacteriophage N15) reference strain

Tail tube terminator protein (TrP) (Gene product 12) (gp12) (Tail-to-head joining protein) (THJP)

TTTP_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

Tail tube terminator protein p142 (TrP-142) (Tail protein p142) (Tail-to-head joining protein p142) (THJP)

pdb 8BCP; 8BCU; 9ILV

TTTP_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

Tail tube terminator protein (TrP) (Gene product U) (gpU) (Minor tail protein U) (Tail sheath-stabilizing protein) (Tail-to-head joining protein) (THJP)

pdb 1Z1Z; 3FZ2; 3FZB; 8IYD; 8K37; 8XOW; 8XPM; 8XQB

TTTP_BPLP2
Lactococcus phage p2 (Lactococcus lactis bacteriophage p2)

1 entry

Tail tube protein (TTP) (Gene product V) (gpV) (Major tail protein V)

TUBE_LAMBD
Escherichia phage lambda (Bacteriophage lambda) reference strain

pdb 2K4Q; 2L04; 6P3E; 7T2E; 7T4F; 8IYD; 8IYK; 8IYL; 8K35; 8K36; 8K37; 8KGE; 8XPM

2 entries

Tail fiber assembly protein U (Gene product 50) (gp50) (Gene product U) (gpU)

Select_allDeselect_all
U1_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain

pdb 5YVQ

U1_BPP1
Escherichia phage P1 (Bacteriophage P1) reference strain

Tail fiber assembly protein U (Gene product U) (gpU)

2 entries

Tail fiber assembly protein U' (Gene product U') (gpU')

Select_allDeselect_all
U2_BPMU
Escherichia phage Mu (Bacteriophage Mu) reference strain
U2_BPP1
Escherichia phage P1 (Bacteriophage P1) reference strain

2 entries

Tail assembly protein Gp24 (Gene product 24) (Gp24) (Minor tail protein Gp24)

Select_allDeselect_all
VG24_BPMD2
Mycobacterium phage D29 (Mycobacteriophage D29) reference strain
VG24_BPML5
Mycobacterium phage L5 (Mycobacteriophage L5) reference strain