Corticoviridae (taxid:10659)

VIRION

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Icosahedral pseudo T=21 capsid 56 nm in diameter, composed of 1200 P1 (spike) and 60 P2 (capsid) proteins. The pentameric receptor-binding spikes are protruding from the 12 fivefold axes. The capsid encloses an internal lipid core containing the structural proteins P3 to P9.

  • Double jelly roll-fold major capsid protein [MCP P2]
  • Triple jelly roll-fold penton capsid protein [Spike P1]
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GENOME

Circular, supercoiled dsDNA genome of about 10 kb encoding for 21 proteins. Displays a very high number of negative supercoils.

GENE EXPRESSION

The genome is organized in three operons.

ENZYMES

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attach to target cell
  2. Injection: viral DNA is injected in host cell cytoplasm
  3. Transcription and translation of early genes
  4. Replication of genomic DNA via a rolling-circle mechanism
  5. Transcription and translation of late genes
  6. Capsid proteins polymerize around a lipoprotein vesicle translocated in the cytoplasm by virion assembly factors.
  7. Genomic DNA is packaged in new virions
  8. Mature virions are released from the cell by lysis

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

21 entries grouped by strain

21 entries

Pseudoalteromonas phage PM2 (Bacteriophage PM2) reference strain

Select_allDeselect_all
CAPSD_BPPM2 Major capsid protein P2 (Protein II)
P4_BPPM2 Protein P4 (Protein IV)
P6_BPPM2 Protein P6 (Protein VI)
P5_BPPM2 Protein P5 (Protein V)
SPIKE_BPPM2 Spike protein P1 (Protein I)
P8_BPPM2 Protein P8 (Protein VIII)
P3_BPPM2 Protein P3 (Protein III)
EXLYS_BPPM2 Peptidoglycan hydrolase P7 (Protein VII)
P9_BPPM2 Protein P9 (Protein IX)
P12_BPPM2 Probable replication protein P12 (EC 3.1.-.-) (Protein XII)
GPB_BPPM2 Uncharacterized protein Gp-b*
GPL_BPPM2 Uncharacterized protein Gp-l
GPK_BPPM2 Uncharacterized protein Gp-k
GPJ_BPPM2 Uncharacterized protein Gp-j
GPH_BPPM2 Uncharacterized protein Gp-h
P14_BPPM2 Uncharacterized protein P14 (Protein XIV)
P13_BPPM2 Transcription factor P13 (Protein XIII)
GPE_BPPM2 Uncharacterized protein Gp-e
GPD_BPPM2 Uncharacterized protein Gp-d
GPC_BPPM2 Uncharacterized protein Gp-c
GPA_BPPM2 Uncharacterized protein Gp-a