Leviviridae

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VIRION

Non-enveloped, spherical virion about 26 nm in diameter with T=3 icosahedral symmetry composed of 178 CP proteins and a single A maturation protein .

GENOME

Monopartite, linear, ssRNA(+) genome about 3.4-4.3 kb in size. The 5' end is capped. Encodes 3 (Allelovirus ) or 4 proteins (Levivirus ).

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. Encodes 4 ORFs. Cp protein represses replicase translation by binding a RNA hairpin at the start site of this gene.
Lysis protein is expressed by suppression of termination of an UGA nonsense codon in Allolevivirus genus.

REPLICATION

  1. Adsorption to F pili of target cells induces cleavage and release of the maturation protein.
  2. Genomic RNA enters the bacterium.
  3. Viral proteins are translated.
  4. Viral replicase assembles with host proteins (ribosomal protein S1, translation elongation factors EF-Tu and EF-Ts) to form the active RNA polymerase.
  5. Replication of genomic RNA into a minus strand, which serves as template to produce new positive strand genomes.
  6. Late in infection CP protein bind to a RNA hairpin on the genome, and new virus particles are assembled in the cytoplasm.
  7. Release by cell lysis.

Matching UniProtKB/Swiss-Prot entries

31 entries grouped by strain (browse by keywords)

All proteins are shown (view only 24 complete proteome entries)

4 entries

Enterobacteria phage GA (Bacteriophage GA) reference strain

Select_allDeselect_all
CAPSD_BPGA Capsid protein (CP) (Coat protein)
LYS_BPGA Lysis protein
MATA_BPGA Maturation protein A (MP) (Assembly protein) (A protein)
RDRP_BPGA RNA-directed RNA polymerase beta chain (EC 2.7.7.48) (RNA replicase beta chain)

4 entries

Enterobacteria phage MX1 (Bacteriophage MX1) reference strain

Select_allDeselect_all
A1_BPMX1 Minor capsid protein A1
CAPSD_BPMX1 Capsid protein (CP) (Coat protein)
MATA2_BPMX1 Maturation protein A2 (MP) (A2) (Assembly protein) (A protein)
RDRP_BPMX1 RNA-directed RNA polymerase subunit beta (EC 2.7.7.48) (RNA replicase beta chain)

4 entries

Enterobacteria phage SP (Bacteriophage SP) reference strain

Select_allDeselect_all
A1_BPSP Minor capsid protein A1
CAPSD_BPSP Capsid protein (CP) (Coat protein)
MATA2_BPSP Maturation protein A2 (MP) (A2) (Assembly protein) (A protein)
RDRP_BPSP RNA-directed RNA polymerase subunit beta (EC 2.7.7.48) (RNA replicase beta chain)

4 entries

Escherichia phage MS2 (Bacteriophage MS2) reference strain

Select_allDeselect_all
CAPSD_BPMS2 Capsid protein (CP) (Coat protein)
LYS_BPMS2 Lysis protein (L protein)
MATA_BPMS2 Maturation protein A (MP) (Assembly protein) (A protein)
RDRP_BPMS2 RNA-directed RNA polymerase beta chain (EC 2.7.7.48) (RNA replicase beta chain)

4 entries

Enterobacteria phage fr (Bacteriophage fr)

Select_allDeselect_all
CAPSD_BPFR Capsid protein (CP) (Coat protein)
MATA_BPFR Maturation protein A (MP) (Assembly protein) (A protein)
LYS_BPFR Lysis protein
RDRP_BPFR RNA-directed RNA polymerase beta chain (EC 2.7.7.48) (RNA replicase beta chain)

4 entries

Escherichia phage Qbeta (Bacteriophage Q-beta)

Select_allDeselect_all
A1_BPQBE Minor capsid protein A1 (A1 read-through protein)
CAPSD_BPQBE Capsid protein (CP) (Coat protein)
MATA2_BPQBE Maturation protein A2 (MP) (A2 protein)
RDRP_BPQBE RNA-directed RNA polymerase subunit beta (EC 2.7.7.48) (RNA replicase beta chain) (RNA-directed RNA ...

2 entries

Enterobacteria phage JP34 (Bacteriophage JP34)

Select_allDeselect_all
CAPSD_BPJP3 Capsid protein (CP) (Coat protein)
LYS_BPJP3 Lysis protein

1 entry

Enterobacteria phage R17 (Bacteriophage R17)

CAPSD_BPR17 Capsid protein (CP) (Coat protein)

1 entry

Enterobacteria phage ZR (Bacteriophage ZR)

CAPSD_BPZR Capsid protein (CP) (Coat protein)

1 entry

Enterobacteria phage f2 (Bacteriophage f2)

CAPSD_BPF2 Capsid protein (CP) (Coat protein)

1 entry

Pseudomonas phage PP7 (Bacteriophage PP7)

COAT_BPPP7 Coat protein

1 entry

Pseudomonas phage PRR1 (Bacteriophage PRR1)

COAT_BPPRR Coat protein