Hp1virus

VIRION

Non-enveloped, head-tail structure. Heads are about 60 nm in diameter and tails 135 × 18 nm. The tail is contractile, has 6 long terminal fibers, 6 short spikes and a small base plate. The capsid has an elongated icosahedral symmetry T=7, composed of 72 capsomers (60 hexamers and 12 pentamers). Upon contraction, the tail sheath becomes loose and slides along the tail core.

GENOME

Linear, dsDNA genome of about 33 kb, encoding for about 45 proteins.

GENE EXPRESSION

Genes are transcribed by operons.

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to the target cell through its tail fibers.
  2. Viral exolysin degrades cell wall locally
  3. Ejection of the viral DNA into host cell cytoplasm by contraction of the tail sheath.
  4. Transcription and translation of early genes.
  5. Replication of genomic DNA by rolling circle. Linear molecules are generated from closed circular monomer product by viral terminase proteins.
  6. Transcription and translation of late genes.
  7. Assembly of an empty procapsid and packaging of the genome.
  8. Viral tail fibers assembly and viral tail assembly.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

41 entries grouped by protein (browse by keywords)

1 entry

Putative baseplate protein gp29 (Gene 29 protein) (Gp29)

BP29_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Major capsid protein (Gene product 18) (gp18) (Major head protein) (ORF18)

CAPSD_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Probable tail fiber protein (Gene product 31) (gp31) (ORF31)

FIB31_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Holin

HOLI_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Lysozyme (EC 3.2.1.17) (Endolysin) (Lysis protein) (Muramidase)

LYS_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Probable portal protein (ORF15)

PORTL_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Replication protein (EC 3.1.-.-)

REP_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Repressor protein CI

RPC1_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Capsid assembly scaffolding protein (Gene product 17) (Gp17) (Head morphogenesis protein) (Scaffold protein)

SCAF_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Putative tail protein gp30 (Gene product 30) (gp30)

TAIL1_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Probable tape measure protein (TMP) (Gene product 27) (gp27)

TMP_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Regulatory protein cox

VCOX_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Integrase (EC 2.7.7.-) (EC 3.1.-.-)

VINT_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Probable head completion/stabilization protein (ORF20)

VPL_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Probable terminase, endonuclease subunit (ORF19)

VPM_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Probable terminase, ATPase subunit (ORF16)

VPP_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 23.2 kDa protein in int-C1 intergenic region (ORF1)

YO01_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 7.9 kDa protein in int-C1 intergenic region (ORF16) (ORF2)

YO02_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 8.9 kDa protein in int-C1 intergenic region (ORF17) (ORF3)

YO03_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 8.9 kDa protein in int-C1 intergenic region (ORF18) (ORF4)

YO04_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 19.2 kDa protein in cox-rep intergenic region (ORF21) (ORF5)

YO05_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 14.1 kDa protein in cox-rep intergenic region (ORF22) (ORF6)

YO06_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 7.3 kDa protein in cox-rep intergenic region (ORF23) (ORF7)

YO07_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 10.8 kDa protein in cox-rep intergenic region (ORF24) (ORF8)

YO08_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 9.7 kDa protein in cox-rep intergenic region (ORF25) (ORF9)

YO09_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 11.1 kDa protein in rep-hol intergenic region (ORF10)

YO10_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 8.3 kDa protein in rep-hol intergenic region (ORF11)

YO11_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 18.2 kDa protein in rep-hol intergenic region (ORF12)

YO12_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized adenine-specific methylase (EC 2.1.1.72) (ORF13)

YO13_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 14.9 kDa protein in rep-hol intergenic region (ORF14)

YO14_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 19.2 kDa protein in rep-hol intergenic region (ORF21)

YO21_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 26.0 kDa protein in rep-hol intergenic region (ORF22)

YO22_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Putative tail sheath protein (ORF23)

YO23_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Putative tail tube protein (ORF24)

YO24_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 13.1 kDa protein in lys 3'region (ORF25)

YO25_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 11.3 kDa protein in lys 3'region (ORF26)

YO26_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 12.7 kDa protein in lys 3'region (ORF28)

YO28_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 23.3 kDa protein in lys 3'region (ORF32)

YO32_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 28.3 kDa protein in lys 3'region (ORF33)

YO33_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 20.8 kDa protein in lys 3'region (ORF34)

YO34_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain

1 entry

Uncharacterized 58.7 kDa protein in lys 3'region (ORF35)

YO35_BPHC1
Haemophilus phage HP1 (strain HP1c1) (Bacteriophage HP1) reference strain