Bromoviridae

VIRION

Non enveloped, icosahedral or bacilliform 26-35 nm in diameter. Symmetry icosahedral (T = 3, or T = 1 ). Three genomic and one subgenomic segments are encapsidated in distinct particles, resulting in several different types of virion.

GENOME

Segmented, tripartite linear ssRNA(+) genome composed of RNA1, RNA2, RNA3. Each genomic segment has a 3' tRNA-like structure and a 5’cap.

GENE EXPRESSION

Genomic RNAs serve as messenger RNAs. RNA1 and RNA2 encode respectively proteins 1a and 2a, both involved in genome replication and internal transcription of sgRNA4 from the minus-strand copy of RNA3. RNA3 and sgRNA4 are translated respectively into movement and capsid proteins.
Cucumovirus and ilarvirus have an additional overlapping ORF2b.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. Expression of protein 1a and 2a to produce replication proteins.
  4. Replication occurs in viral factories made of membrane vesicles derived from the ER (spherules). A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Subgenomic RNA4 is translated producing capsid proteins.
  7. Assembly of new virus particles.
  8. Viral movement protein triggers the formation of tubular structures that mediate virion cell-to-cell transfer via a tubule-guided mechanism.

Host-virus interaction

Suppression of RNA silencing

Cucumovirus (and possibly ilarvirus) protein 2b acts as a suppressor of RNA silencing .

Matching UniProtKB/Swiss-Prot entries

109 entries grouped by strain (browse by keywords)

All proteins are shown (view only 44 complete proteome entries)

5 entries

Cucumber mosaic virus (strain FNY) (CMV) reference strain

Select_allDeselect_all
1A_CMVFN Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
2B_CMVFN Suppressor of silencing 2b (Protein 2b)
CAPSD_CMVFN Capsid protein (CP) (Coat protein)
MVP_CMVFN Movement protein (MP) (Protein 3A)
RDRP_CMVFN RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

5 entries

Cucumber mosaic virus (strain Q) (CMV) reference strain

Select_allDeselect_all
1A_CMVQ Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
2B_CMVQ Suppressor of silencing 2b (Protein 2b)
CAPSD_CMVQ Capsid protein (CP) (Coat protein)
MVP_CMVQ Movement protein (MP) (Protein 3A)
RDRP_CMVQ RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

5 entries

Tobacco streak virus (strain WC) (TSV) reference strain

Select_allDeselect_all
2B_TOBSV Suppressor of silencing 2b (Protein 2b)
1A_TOBSV Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_TOBSV Capsid protein (CP) (Coat protein)
MVP_TOBSV Movement protein (MP) (Protein 3A)
RDRP_TOBSV RNA-directed RNA polymerase 2a (2a pol) (EC 2.7.7.48) (2a polymerase)

5 entries

Tomato aspermy virus (TAV) reference strain

Select_allDeselect_all
1A_TAV Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
2B_TAV Suppressor of silencing 2b (Protein 2b)
CAPSD_TAV Capsid protein (CP) (Coat protein)
MVP_TAV Movement protein (MP) (Protein 3A)
RDRP_TAV RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Alfalfa mosaic virus (strain 425 / isolate Leiden) reference strain

Select_allDeselect_all
1A_AMVLE Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_AMVLE Capsid protein (CP) (Coat protein)
MVP_AMVLE Movement protein (MP) (Protein 3A)
RDRP_AMVLE RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Brome mosaic virus (BMV) reference strain

Select_allDeselect_all
1A_BMV Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_BMV Capsid protein (CP) (Coat protein)
MVP_BMV Movement protein (MP) (Protein 3A)
RDRP_BMV RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Olive latent virus 2 (isolate Italy) (OLV-2) reference strain

Select_allDeselect_all
1A_OLV2I Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_OLV2I Capsid protein (CP) (Coat protein)
MVP_OLV2I Movement protein (MP) (Protein 3A)
RDRP_OLV2I RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Pelargonium zonate spot virus (isolate Tomato/Italy/1982) (PZSV) (Pelargonium zonate spot virus (isolate Tomato)) reference strain

Select_allDeselect_all
1A_PZSVT Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_PZSVT Capsid protein (CP) (Coat protein)
MVP_PZSVT Movement protein (MP) (Protein 3A)
RDRP_PZSVT RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Broad bean mottle virus

Select_allDeselect_all
1A_BBMV Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_BBMV Capsid protein (CP) (Coat protein)
MVP_BBMV Movement protein (MP) (Protein 3A)
RDRP_BBMV RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Cowpea chlorotic mottle virus (CCMV)

Select_allDeselect_all
1A_CCMV Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_CCMV Capsid protein (CP) (Coat protein)
MVP_CCMV Movement protein (MP) (Protein 3A)
RDRP_CCMV RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Cucumber mosaic virus (strain Ixora) (CMV)

Select_allDeselect_all
1A_CMVIX Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_CMVIX Capsid protein (CP) (Coat protein)
MVP_CMVIX Movement protein (MP) (Protein 3A)
RDRP_CMVIX RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Cucumber mosaic virus (strain NT9) (CMV)

Select_allDeselect_all
1A_CMVNT Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_CMVNT Capsid protein (CP) (Coat protein)
MVP_CMVNT Movement protein (MP) (Protein 3A)
RDRP_CMVNT RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Cucumber mosaic virus (strain Y) (CMV)

Select_allDeselect_all
1A_CMVY Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_CMVY Capsid protein (CP) (Coat protein)
MVP_CMVY Movement protein (MP) (Protein 3A)
RDRP_CMVY RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

4 entries

Peanut stunt virus (strain J) (PSV)

Select_allDeselect_all
1A_PSVJ Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_PSVJ Capsid protein (CP) (Coat protein)
MVP_PSVJ Movement protein (MP) (Protein 3A)
RDRP_PSVJ RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

3 entries

Cucumber mosaic virus (strain As) (CMV)

Select_allDeselect_all
CAPSD_CMVAS Capsid protein (CP) (Coat protein)
MVP_CMVAS Movement protein (MP) (Protein 3A)
RDRP_CMVAS RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

3 entries

Cucumber mosaic virus (strain Iizuka) (CMV)

Select_allDeselect_all
1A_CMVII Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_CMVII Capsid protein (CP) (Coat protein)
RDRP_CMVII RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

3 entries

Cucumber mosaic virus (strain Kor) (CMV)

Select_allDeselect_all
CAPSD_CMVKO Capsid protein (CP) (Coat protein)
MVP_CMVKO Movement protein (MP) (Protein 3A)
RDRP_CMVKO RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

3 entries

Cucumber mosaic virus (strain O) (CMV)

Select_allDeselect_all
1A_CMVO Replication protein 1a [Includes: ATP-dependent helicase (EC 3.6.4.-); Methyltransferase (EC ...
CAPSD_CMVO Capsid protein (CP) (Coat protein)
MVP_CMVO Movement protein (MP) (Protein 3A)

2 entries

Alfalfa mosaic virus (strain 425 / isolate Madison)

Select_allDeselect_all
CAPSD_AMVMA Capsid protein (CP) (Coat protein)
MVP_AMVMA Movement protein (MP) (Protein 3A)

2 entries

Alfalfa mosaic virus (strain Strasbourg)

Select_allDeselect_all
CAPSD_AMVST Capsid protein (CP) (Coat protein)
MVP_AMVST Movement protein (MP) (Protein 3A)

2 entries

Alfalfa mosaic virus (strain YSMV)

Select_allDeselect_all
CAPSD_AMVYS Capsid protein (CP) (Coat protein)
MVP_AMVYS Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain C7-2) (CMV)

Select_allDeselect_all
CAPSD_CMVC7 Capsid protein (CP) (Coat protein)
MVP_CMVC7 Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain CS) (CMV)

Select_allDeselect_all
CAPSD_CMVCS Capsid protein (CP) (Coat protein)
MVP_CMVCS Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain FT) (CMV)

Select_allDeselect_all
CAPSD_CMVFT Capsid protein (CP) (Coat protein)
MVP_CMVFT Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain Kin) (CMV)

Select_allDeselect_all
CAPSD_CMVKI Capsid protein (CP) (Coat protein)
MVP_CMVKI Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain M) (CMV)

Select_allDeselect_all
CAPSD_CMVM Capsid protein (CP) (Coat protein)
MVP_CMVM Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain M48) (CMV)

Select_allDeselect_all
CAPSD_CMVM4 Capsid protein (CP) (Coat protein)
MVP_CMVM4 Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain N) (CMV)

Select_allDeselect_all
CAPSD_CMVN Capsid protein (CP) (Coat protein)
MVP_CMVN Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain Pepo) (CMV)

Select_allDeselect_all
CAPSD_CMVPE Capsid protein (CP) (Coat protein)
MVP_CMVPE Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain S) (CMV)

Select_allDeselect_all
CAPSD_CMVS Capsid protein (CP) (Coat protein)
MVP_CMVS Movement protein (MP) (Protein 3A)

2 entries

Cucumber mosaic virus (strain Trk7) (CMV)

Select_allDeselect_all
CAPSD_CMVTR Capsid protein (CP) (Coat protein)
MVP_CMVTR Movement protein (MP) (Protein 3A)

1 entry

Cucumber mosaic virus (strain B) (CMV)

RDRP_CMVB RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

1 entry

Cucumber mosaic virus (strain Banana) (CMV)

CAPSD_CMVBA Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain C) (CMV)

CAPSD_CMVC Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain DKRD) (CMV)

CAPSD_CMVDK Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain E5) (CMV)

CAPSD_CMVE5 Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain FC) (CMV)

CAPSD_CMVFC Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain I17F) (CMV)

CAPSD_CMVI1 Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain K) (CMV)

RDRP_CMVK RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

1 entry

Cucumber mosaic virus (strain MB-8) (CMV)

RDRP_CMVMB RNA-directed RNA polymerase 2a (protein 2a) (EC 2.7.7.48)

1 entry

Cucumber mosaic virus (strain P6) (CMV)

CAPSD_CMVP6 Capsid protein (CP) (Coat protein)

1 entry

Cucumber mosaic virus (strain WL) (CMV)

CAPSD_CMVWL Capsid protein (CP) (Coat protein)