Inhibition of host DNA replication by virus (kw:KW-1248)

Some bacterial viruses shut off host DNA replication to arrest host growth. The advantage for the virus might be to have all the pool of nucleotides available for its own replication.
Bacteriophage N4 (Gp8 protein) and Staphylococcus bacteriophages for example shut off the host DNA replication by inhibiting the processivity clamp of the replicating polymerase .

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