Luteoviridae

VIRION

Non-enveloped, spherical virion about 25-30 nm in diameter with T=3 icosahedral symmetry composed of 180 CP proteins.

GENOME

Monopartite, linear, ssRNA(+) genome of 5.3-5.7 kb. Poleroviruses and enamoviruses have a VPg bound at the 5' end. There is no poly(A) tail or tRNA-like structure at the 3' end.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The viral polymerase is expressed by a ribosomal frameshifting at the end of ORF1.

Depending on the genus, several proteins can be produced by Leaky scanning. Suppression of termination of the CP stop codon produces CP-RTD (CP extended), the capsid subunit essential for aphid transmission.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA ORF1 and ORF2 are translated to produce the RdRp fusion protein.
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Expression of the 3' coterminal sgRNAs. Traduction of these sgRNAs yields the capsid, CP-RTD and movement proteins.
  7. Virus assembly.
  8. Viral movement protein probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Polerovirus protein P0 acts as a suppressor of RNA silencing by targeting Argonaute 1 for degradation .

Enamovirus protein P0 acts as a suppressor of RNA silencing by targeting Argonaute 1 for degradation

Barley yellow dwarf virus protein P6 acts as a suppressor of RNA silencing

Matching UniProtKB/Swiss-Prot entries

50 entries grouped by strain (browse by keywords)

All proteins are shown (view only 34 complete proteome entries)

8 entries

Potato leafroll virus (strain Potato/Scotland/strain 1/1984) (PLrV) reference strain

Select_allDeselect_all
CAPSD_PLRV1 Major capsid protein (Coat protein) (CP)
MCAPS_PLRV1 Minor capsid protein P3-RTD (P74) (Readthrough protein) (RT protein)
P0_PLRV1 Suppressor of silencing P0 (28 kDa protein) (Protein ORF0)
P6_PLRV1 Uncharacterized protein P6 (ORF6 protein)
MVP_PLRV1 Movement protein (MP) (17 kDa protein)
P1_PLRV1 Protein P1 (69.7 kDa protein) (Genome-linked protein precursor) (Protein ORF1) [Cleaved into: Serine ...
RAP1_PLRV1 Replication-associated protein (Rap1)
RDRP_PLRV1 Protein P1-P2 [Cleaved into: Serine protease (EC 3.4.21.-); RNA-directed RNA polymerase (EC ...

7 entries

Turnip yellows virus (isolate FL-1) (TuYV) (BWYV-FL1) reference strain

Select_allDeselect_all
CAPSD_TYYVF Major capsid protein (Coat protein) (CP)
MCAPS_TYYVF Minor capsid protein P3-RTD (P74) (Readthrough protein) (RT protein)
ORF3A_TYYVF Protein ORF3a
MVP_TYYVF Movement protein (MP) (20 kDa protein)
P0_TYYVF Suppressor of silencing P0 (29 kDa protein) (Protein ORF0)
P1_TYYVF Protein P1 (66.2 kDa protein) (Genome-linked protein precursor) (Protein ORF1) [Cleaved into: Serine ...
RDRP_TYYVF Protein P1-P2 [Cleaved into: Serine protease (EC 3.4.21.-); RNA-directed RNA polymerase (EC ...

6 entries

Barley yellow dwarf virus (isolate PAV) (BYDV) reference strain

Select_allDeselect_all
CAPSD_BYDVP Major capsid protein (Coat protein) (CP)
MCAPS_BYDVP Minor capsid protein (P74) (Readthrough protein) (RT protein)
ORF7_BYDVP Uncharacterized protein ORF7
MVP_BYDVP Movement protein (MP) (17 kDa protein)
ORF6_BYDVP Uncharacterized protein ORF6
RDRP_BYDVP Putative RNA-directed RNA polymerase (EC 2.7.7.48)

5 entries

Pea enation mosaic virus-1 (strain WSG) (PEMV-1) reference strain

Select_allDeselect_all
CAPSD_PEMVW Major capsid protein (Coat protein) (CP)
MCAPS_PEMVW Minor capsid protein P3-RTD (Readthrough protein) (RT protein)
P0_PEMVW Suppressor of silencing P0 (ORF0 protein)
P1_PEMVW Protein P1 (Genome-linked protein precursor) (ORF1 protein) [Cleaved into: Serine protease (EC ...
RDRP_PEMVW Protein P1-P2 [Cleaved into: Serine protease (EC 3.4.21.-); RNA-directed RNA polymerase (EC ...

8 entries

Potato leafroll virus (strain Potato/Netherlands/Wageningen/1989) (PLrV)

Select_allDeselect_all
CAPSD_PLRVW Major capsid protein (Coat protein) (CP)
MCAPS_PLRVW Minor capsid protein P3-RTD (P74) (Readthrough protein) (RT protein)
P0_PLRVW Suppressor of silencing P0 (28 kDa protein) (Protein ORF0)
P6_PLRVW Uncharacterized protein P6 (ORF6 protein)
MVP_PLRVW Movement protein (MP) (17 kDa protein)
P1_PLRVW Protein P1 (69.7 kDa protein) (Genome-linked protein precursor) (Protein ORF1) [Cleaved into: Serine ...
RDRP_PLRVW Protein P1-P2 [Cleaved into: Serine protease (EC 3.4.21.-); RNA-directed RNA polymerase (EC ...
RAP1_PLRVW Replication-associated protein (Rap1)

3 entries

Barley yellow dwarf virus (isolate MAV-PS1) (BYDV)

Select_allDeselect_all
CAPSD_BYDV1 Major capsid protein (Coat protein) (CP)
MVP_BYDV1 Movement protein (MP) (17 kDa protein)
RDRP_BYDV1 Putative RNA-directed RNA polymerase (EC 2.7.7.48)

3 entries

Barley yellow dwarf virus (isolate P-PAV) (BYDV)

Select_allDeselect_all
CAPSD_BYDVR Major capsid protein (Coat protein) (CP)
MVP_BYDVR Movement protein (MP) (17 kDa protein)
RDRP_BYDVR Putative RNA-directed RNA polymerase (EC 2.7.7.48)

2 entries

Barley yellow dwarf virus (isolate NY-RPV) (BYDV)

Select_allDeselect_all
CAPSD_BYDVN Major capsid protein (Coat protein) (CP)
MVP_BYDVN Movement protein (MP) (17 kDa protein)

2 entries

Bean leafroll virus (BLRV)

Select_allDeselect_all
CAPSD_BLRV Major capsid protein (Coat protein) (CP)
MVP_BLRV Movement protein (MP) (16 kDa protein)

2 entries

Potato leafroll virus (PLrV)

Select_allDeselect_all
CAPSD_PLRV Major capsid protein (Coat protein) (CP)
MVP_PLRV Movement protein (MP) (17 kDa protein) (MP17)

2 entries

Potato leafroll virus (strain Potato/Canada/Rowhani/1979) (PLrV)

Select_allDeselect_all
CAPSD_PLRVR Major capsid protein (Coat protein) (CP)
MVP_PLRVR Movement protein (MP) (17 kDa protein)

1 entry

Barley yellow dwarf virus (isolate MAV) (BYDV)

CAPSD_BYDVM Major capsid protein (Coat protein) (CP)

1 entry

Beet western yellows virus (isolate GB1) (BWYV)

MVP_BWYVG Movement protein (MP) (20 kDa protein)