Potyviridae

VIRION

Non-enveloped, flexuous, filamentous, of one (650-900 nm) or two (500-600 and 200-300 nm) lengths x 12-15 nm in diameter. Symmetry helical. Presence of characteristic inclusion bodies within infected plant cells.

GENOME

Monopartite or bipartite, linear, ssRNA(+) genome of 8,5-12 kb in size. 3' terminus has a poly (A) tract. 5' terminus has a genome-linked protein (VPg).

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The genomic RNA (or genome segments) is translated into polyprotein(s) subsequently processed by virus-encoded proteases into functional products. P3N-PIPO is expressed by a polymerase slippage mechanism from the P3 ORF and probably acts as a movement protein.


Cleavage sites in the family Potyviridae

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce a polyprotein which is processed by viral proteases into the RdRp protein and structural proteins.
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Virus assembly in the cytoplasm.
  7. Viral movement protein P3N-PIPO probably mediates virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

P1 proteins of TriMV and Wheat streak mosaic virus function as suppressors of RNA silencing .
Sweet potato mild mottle ipomovirus P1 protein acts as a suppressor of RNA silencing .
Potyviruses HC-PRO functions as a suppressor of RNA silencing .

Matching UniProtKB/Swiss-Prot entries

64 entries grouped by strain (browse by keywords)

All proteins are shown (view only 62 complete proteome entries)

2 entries

Barley yellow mosaic virus (isolate China/Yancheng/1998) (BaYMV) reference strain

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POL1_BAYMY Genome polyprotein 1 [Cleaved into: Protein P3; 6 kDa protein 1 (6K1); Cytoplasmic inclusion protein ...
POL2_BAYMY Genome polyprotein 2 [Cleaved into: Helper component proteinase (HC-pro) (EC 3.4.22.45); 70 kDa ...

2 entries

Potato virus Y (strain N) (PVY) reference strain

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POLG_PVYN Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_PVYN P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

1 entry

Blackberry virus Y (isolate Blackberry plant/USA:Arkansas/C3ARK/2005) (BVY) reference strain

POLG_BVY3 Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

1 entry

Brome streak virus (strain 11-Cal) (BStV) (Brome streak mosaic rymovirus) reference strain

POLG_BSTV1 Genome polyprotein [Cleaved into: P1 proteinase (N-terminal protein); Helper component proteinase ...

1 entry

Ryegrass mosaic virus (isolate Denmark/Danish) (RGMV) reference strain

POLG_RGMVD Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

1 entry

Sweet potato mild mottle virus (isolate Salazar) (SPMMV) reference strain

POLG_SPMMV Genome polyprotein [Cleaved into: P1 proteinase (N-terminal protein); Helper component proteinase ...

2 entries

Barley mild mosaic virus (strain Na1) (BaMMV)

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POL2_BAMMN Genome polyprotein 2 [Cleaved into: Helper component proteinase (HC-pro) (EC 3.4.22.45); 70 kDa ...
POL1_BAMMN Genome polyprotein 1 [Cleaved into: Protein P3; 6 kDa protein 1 (6K1); Cytoplasmic inclusion protein ...

2 entries

Barley yellow mosaic virus (isolate Germany) (BaYMV)

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POL1_BAYMG Genome polyprotein 1 [Cleaved into: Protein P3; 6 kDa protein 1 (6K1); Cytoplasmic inclusion protein ...
POL2_BAYMG Genome polyprotein 2 [Cleaved into: Helper component proteinase (HC-pro) (EC 3.4.22.45); 70 kDa ...

2 entries

Barley yellow mosaic virus (strain Japanese II-1) (BaYMV)

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POL2_BAYMJ Genome polyprotein 2 [Cleaved into: Helper component proteinase (HC-pro) (EC 3.4.22.45); 70 kDa ...
POL1_BAYMJ Genome polyprotein 1 [Cleaved into: Protein P3; 6 kDa protein 1 (6K1); Cytoplasmic inclusion protein ...

2 entries

Bean common mosaic necrosis virus (strain NL-3) (BCMNV) (Bean common mosaic virus serotype A (strain NL-3))

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MVP_BCMNN P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_BCMNN Genome polyprotein [Cleaved into: P1 proteinase (N-terminal protein); Helper component proteinase ...

2 entries

Bean yellow mosaic virus

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MVP_BYMV P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_BYMV Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Beet mosaic virus (BtMV)

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MVP_BTMV P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_BTMV Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Lettuce mosaic virus (strain 0 / isolate French) (LMV)

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POLG_LMV0 Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_LMV0 P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Lettuce mosaic virus (strain E) (LMV)

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POLG_LMVE Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_LMVE P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Papaya ringspot virus (strain P / mutant HA)

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MVP_PRSVH P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_PRSVH Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Pea seed-borne mosaic virus (strain DPD1)

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POLG_PSBMV Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_PSBMV P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Peanut mottle virus (strain M)

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POLG_PEMVM Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_PEMVM P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Pepper mottle virus (isolate California) (PeMV) (PepMoV C)

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POLG_PEMVC Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_PEMVC P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Plum pox potyvirus (isolate NAT) (PPV)

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MVP_PPVNA P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_PPVNA Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Plum pox potyvirus (strain D) (PPV)

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POLG_PPVD Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_PPVD P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Plum pox potyvirus (strain SK 68) (PPV)

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POLG_PPVSK Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_PPVSK P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Potato virus A (PVA)

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POLG_PVMA Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_PVMA P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Potato virus Y (strain Hungarian) (PVY)

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POLG_PVYHU Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_PVYHU P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Soybean mosaic virus (strain G2) (SMV)

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POLG_SBMVG Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_SBMVG P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Soybean mosaic virus (strain N) (SMV)

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POLG_SBMVN Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_SBMVN P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Tobacco etch virus (TEV)

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POLG_TEV Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_TEV P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Tobacco vein mottling virus (TVMV)

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MVP_TVMV P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_TVMV Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Turnip mosaic virus (strain Japanese) (TuMV)

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POLG_TUMVJ Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_TUMVJ P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Turnip mosaic virus (strain Quebec) (TuMV)

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POLG_TUMVQ Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_TUMVQ P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Zucchini yellow mosaic virus (strain California) (ZYMV)

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MVP_ZYMVC P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_ZYMVC Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

2 entries

Zucchini yellow mosaic virus (strain Reunion Island) (ZYMV)

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POLG_ZYMVR Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...
MVP_ZYMVR P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...

2 entries

Zucchini yellow mosaic virus (strain Singapore) (ZYMV)

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MVP_ZYMVS P3N-PIPO polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper ...
POLG_ZYMVS Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

1 entry

Barley mild mosaic virus (strain ASL) (BaMMV)

POL2_BAMMA Genome polyprotein 2 [Cleaved into: Helper component proteinase (HC-pro) (EC 3.4.22.45); 70 kDa ...

1 entry

Barley mild mosaic virus (strain UK-F) (BaMMV)

POL2_BAMMU Genome polyprotein 2 [Cleaved into: Helper component proteinase (HC-pro) (EC 3.4.22.45); 70 kDa ...

1 entry

Plum pox potyvirus (strain Rankovic) (PPV)

POLG_PPVRA Genome polyprotein [Cleaved into: P1 proteinase (EC 3.4.-.-) (N-terminal protein); Helper component ...

1 entry

Triticum mosaic virus (isolate Triticum aestivum/United States/U06-123/2006) (TriMV)

POLG_TRMVU Genome polyprotein [Cleaved into: P1 proteinase (N-terminal protein) (EC 3.4.-.-); Helper component ...