T5virus

VIRION

Non-enveloped, head-tail structure. The capsid is about 90 nm in diameter, with a T=13 icosahedral symmetry . It is composed of 11 pentamers at the vertices and 120 hexamers on the faces. The tail is about 160 nm in length and 9 nm in width, with a subterminal disk and 3 long kinked fibers (120 nm). There is also a conical tip with a single straight central fiber (50 nm).

GENOME

Linear, dsDNA genome of about 121 kb, containing about 160 genes.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
  2. Viral exolysin degrades host cell wall locally.
  3. Ejection by long flexible tail ejection system: viral DNA is injected in host cell cytoplasm.
  4. Transcription and translation of early genes.
  5. Replication of genomic DNA by DNA strand displacement replication.
  6. Transcription and translation of late genes
  7. Assembly of an empty procapsid and packaging of the genome.
  8. Viral tail fibers assembly and viral tail assembly.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

45 entries grouped by protein (browse by keywords)

All proteins are shown (view only 43 complete proteome entries)

1 entry

Protein A1

A1_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

2 entries

Protein A2

Select_allDeselect_all
A2_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain
A2_BPBF2
Escherichia phage Bf23 (Enterobacteria phage BF23)

Protein A2-A3

1 entry

Probable baseplate hub protein (BHP) (Tail protein pb3)

BPPB3_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Major capsid protein (Capsid protein pb8) (Major head protein)

CAPSD_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Tail completion protein (Tail protein p143)

COMPL_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Protein D14

D14_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Putative transcription factor D5

D5_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Decoration protein (Capsid protein pb10)

DECO_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Distal tail protein (Dit) (Tail protein pb9)

DIT_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

5'-deoxynucleotidase (EC 3.1.3.89) (Deoxynucleoside-5'-monophosphatase) (5'-dNMPase) (Protein dmp)

DMP_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Deoxynucleoside-5'-monophosphate kinase (EC 2.7.4.13)

DNMK_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-)

DPOL_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)

DUT_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Putative endonuclease (EC 3.1.-.-)

ENDO1_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Putative endonuclease (EC 3.1.-.-)

ENDO2_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Nicking endonuclease (EC 3.1.21.-)

ENDON_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

L-alanyl-D-glutamate peptidase (EC 3.4.24.-) (Endolysin) (Lysozyme)

ENLYS_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Probable exonuclease subunit 1 (EC 3.1.11.-) (D12)

EXO1_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Probable exonuclease subunit 2 (EC 3.1.11.-) (D13)

EXO2_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

T5 flap endonuclease (T5FEN) (EC 3.1.11.-) (5'-3' exonuclease) (Exodeoxyribonuclease) (EC 3.1.11.3)

EXO5_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Probable central straight fiber (Tail protein pb4)

FIBC_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

L-shaped tail fiber protein pb1 (LTF) (EC 3.4.21.-) (Tail protein pb1)

FIBL1_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

L-shaped tail fiber protein p132

FIBL2_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Dihydrofolate reductase (EC 1.5.1.3)

FRD_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Head completion protein (HCP) (p144)

HCP_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Probable helicase D10 (EC 3.6.4.-) (Protein D10)

HEL10_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Holin

HOLIN_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Lytic conversion lipoprotein

LLP_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Putative replication origin binding protein (D2 helicase)

OBP_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Portal protein (Capsid protein pb7)

PORTL_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Prohead protease (EC 3.4.21.-)

PRO_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Receptor-binding protein (RBP) (Tail protein pb5)

RBP5_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Probable ssDNA-binding protein (Protein D11)

SSDNA_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Minor tail protein (Tail protein p140)

TAIL1_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Terminase, large subunit (EC 3.1.-.-) (DNA-packaging protein)

TERL_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Probable terminase, small subunit

TERS_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

H-N-H endonuclease F-TflI (EC 3.1.21.-) (HNH endodeoxyribonuclease F-TflI) (HNH endonuclease F-TflI)

TFLI_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

H-N-H endonuclease F-TflII (EC 3.1.21.-) (HNH endodeoxyribonuclease F-TflII) (HNH endonuclease F-TflII)

TFLII_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

H-N-H endonuclease F-TflIV (EC 3.1.21.-) (HNH endodeoxyribonuclease F-TflIV) (HNH endonuclease F-TflIV)

TFLIV_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Probable thymidylate synthase (EC 2.1.1.45)

THY_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Probable tape measure protein (Tail protein pb2)

TMP_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Tail tube terminator protein (TrP) (Tail protein p142) (Tail-to-head joining protein) (THJP)

TTTP_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Tail tube protein (TTP) (Tail protein pb6)

TUBE_BPT5
Escherichia phage T5 (Enterobacteria phage T5) reference strain

1 entry

Uncharacterized 9.2 kDa protein

Y9KD_BPBF2
Escherichia phage Bf23 (Enterobacteria phage BF23)