Non-enveloped, head-tail structure. The head is about 60 nm in diameter and consists of 72 capsomers (T=7, laevo).


Linear, dsDNA genome of about 48 kb, containing about 70 genes.




  1. Adsorption: The phage attaches to target cell adhesion receptors through its tail fibers.
  2. The baseplate of the virion attaches to the entry receptor.
  3. Ejection of the viral DNA into host cell cytoplasm by long flexible tail ejection system.
  4. Transcription and translation of early genes.
  5. Replication of genomic DNA by theta replication.
  6. Replication of genomic DNA by rolling circle.
  7. Transcription and translation of late genes.
  8. Assembly of empty procapsids and viral genome packaging.
  9. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

170 entries grouped by strain (browse by keywords)

All proteins are shown (view only 86 complete proteome entries)

61 entries

Escherichia phage lambda (Bacteriophage lambda) reference strain

CAPSD_LAMBD Major capsid protein (Gene product E) (gpE) (Major head protein)
COMPL_LAMBD Tail completion protein Z (Gene product Z) (GpZ) (Minor tail protein Z) (Tail terminator protein)
DECO_LAMBD Capsid decoration protein (Auxiliary protein D) (Gene product D) (gpD) (Major capsid protein D)
EXO_LAMBD Exonuclease (EC
EA47_LAMBD Protein ea47
EA22_LAMBD Protein ea22
EA31_LAMBD Protein ea31
EA85_LAMBD Protein ea8.5
ENLYS_LAMBD Endolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)
EA10_LAMBD Protein ea10
EA59_LAMBD Protein ea59
FI_LAMBD DNA-packaging protein FI
FII_LAMBD Head-tail connector protein FII (Head-tail joining protein) (Minor capsid protein FII)
FIBER_LAMBD Tail fiber protein (stf) (Gene product 27) (gp27)
GAM_LAMBD Host-nuclease inhibitor protein gam
GT_LAMBD Tail assembly protein GT (Gene product GT) (gpGT) (Minor tail protein GT)
G_LAMBD Tail assembly protein G (Gene product G) (gpG) (Minor tail protein G) (Tail assembly chaperone) ...
NINB_LAMBD Protein ninB
NIND_LAMBD Protein ninD
NING_LAMBD Protein ninG
NINE_LAMBD Protein ninE (Nin60)
NINF_LAMBD Protein ninF
NINH_LAMBD Protein ninH
PORTL_LAMBD Portal protein B (GpB) (Minor capsid protein B) [Cleaved into: Protein B*]
PP_LAMBD Serine/threonine-protein phosphatase (EC
SCAF_LAMBD Capsid assembly protease C (EC 3.4.21.-) (Gene product C) (GPC) (Minor capsid protein C)
SIEB_LAMBD Superinfection exclusion protein B
TERL_LAMBD Terminase, large subunit (EC (DNA-packaging protein A) (Large terminase protein) (gpA)
TIPM_LAMBD Tail tip protein M
TERS_LAMBD Terminase small subunit (DNA-packaging protein Nu1) (Gene product Nu1) (gpNu1)
TIPL_LAMBD Tail tip protein L
TFA_LAMBD Tail fiber assembly protein
TMP_LAMBD Tape measure protein (TMP) (Gene product H) (gpH) (Minor tail protein H) [Cleaved into: Entry ...
TIPJ_LAMBD Tip attachment protein J (Central tail fiber) (Host specificity protein J)
HCP_LAMBD Head completion protein (HCP) (Head-tail joining protein W) (gpW)
HOLIN_LAMBD Antiholin (Lysis inhibitor S-107)
RAL_LAMBD Restriction inhibitor protein ral (Antirestriction protein)
REGQ_LAMBD Antitermination protein Q
REXA_LAMBD Protein rexA
REXB_LAMBD Protein rexB
REGN_LAMBD Antitermination protein N (Regulatory protein N) (PN)
RCRO_LAMBD Regulatory protein cro
RPC1_LAMBD Repressor protein cI
RPC2_LAMBD Transcriptional activator II
RPC3_LAMBD Protease inhibitor III
SPAN2_LAMBD Spanin, outer lipoprotein subunit (o-spanin) (Outer membrane lipoprotein Rz1)
SPAN1_LAMBD Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz)
TIPI_LAMBD Tail tip assembly protein I
TIPK_LAMBD Tail tip assembly protein K (Probable endopeptidase) (EC 3.4.-.-) (Tail assembly protein K)
TUBE_LAMBD Tail tube protein (TTP) (Gene product V) (gpV) (Major tail protein V)
TTTP_LAMBD Tail tube terminator protein (TrP) (Gene product U) (gpU) (Minor tail protein U) (Tail ...
VKIL_LAMBD Protein kil
VLOM_LAMBD Outer membrane protein lom (ORF 206A)
VINT_LAMBD Integrase (EC 2.7.7.-) (EC 3.1.-.-)
VREN_LAMBD Protein ren
VRPO_LAMBD Replication protein O
VBET_LAMBD Recombination protein bet
VXIS_LAMBD Excisionase
VRPP_LAMBD Replication protein P
Y290_LAMBD Uncharacterized nin region protein ORF290
Y64_LAMBD Putative uncharacterized protein ORF64

20 entries

Bacillus phage SPP1 (Bacteriophage SPP1) reference strain

CAPSD_BPSPP Major capsid protein (Gene product 13) (gp13)
COMPL_BPSPP Tail completion protein gp17 (Gene product 17) (gp17) (Head-tail joining protein gp17) (Tail-to-head ...
DECO_BPSPP Decoration protein gp12 (Gene product 12) (gp12)
DIT_BPSPP Distal tail protein (Dit) (Gene product 19.1) (Gp19.1)
ENLYS_BPSPP Endolysin (EC 3.5.1.-) (LysSPP1) (Putative N-acetylmuramoyl-L-alanine amidase)
FIBER_BPSPP Tail spike protein (TSP) (Gene product 21) (Gp21)
GP7_BPSPP Minor head protein GP7 (Accessory head protein gp7)
HCP15_BPSPP Head completion protein gp15 (HCP) (Connector protein gp15) (Gene product 15) (Gp15)
PORTL_BPSPP Portal protein (Gene product 6) (gp6) (Portal vertex protein)
SCAF_BPSPP Capsid assembly scaffolding protein (Gene product 11) (Gp11) (Head morphogenesis protein) (Scaffold ...
TERS_BPSPP Terminase small subunit (G1P) (Terminase, small subunit gp1)
TERL_BPSPP Terminase, large subunit gp2 (EC 3.1.-.-) (DNA-packaging protein G2P) (Gene product 2) (gp2)
TMP_BPSPP Tail tape measure protein gp18 (Gene product 18) (gp18)
HCP16_BPSPP Head completion protein gp16 (Connector protein gp16) (Gene product 16) (Gp16) (Stopper protein ...
HOL24_BPSPP Holin-like protein 24.1 (Gene product 24.1) (gp24.1)
HOL26_BPSPP Putative antiholin
TUBE_BPSPP Tail tube protein gp17.1* (TTP) (Gene product 17.1) (gp17.1) (Major tail protein) (MTP)
YOR5_BPSPP Uncharacterized 10.3 kDa protein in GP2-GP6 intergenic region (ORF 5)
YOR3_BPSPP Uncharacterized 8.5 kDa protein in GP2-GP6 intergenic region (ORF 3)
YOR4_BPSPP Uncharacterized 10.2 kDa protein in GP2-GP6 intergenic region (ORF 4)

1 entry

Bacillus phage phi105 (Bacteriophage phi-105) reference strain

VLYS_BPPH1 Probable holin (Lysis protein)

2 entries

Bacillus phage phi3T (Bacteriophage phi-3T) reference strain

AIMR_BPPHT AimR transcriptional regulator (Arbitrium communication peptide receptor)
AIMP_BPPHT Protein AimP [Cleaved into: Arbitrium peptide]

2 entries

Enterobacteria phage HK97 (Bacteriophage HK97) reference strain

CAPSD_BPHK7 Major capsid protein (Gene product 5) (gp5) (Major head protein) [Cleaved into: Scaffolding domain ...
RUSA_BPHK7 Crossover junction endodeoxyribonuclease rusA (EC (Gp67) (Holliday junction nuclease rusA) ...

1 entry

Escherichia phage lambda (Bacteriophage lambda)

BOR_LAMBD Lipoprotein bor

17 entries

Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21)

CAPSD_BPP21 Major capsid protein (Gene product 7) (gp7) (Major head protein)
DECO_BPP21 Head decoration protein (Head protein GPshp)
NINB_BPP21 Protein ninB
NINE_BPP21 Protein ninE
NING_BPP21 Protein ninG
NINF_BPP21 Protein ninF
PORTL_BPP21 Portal protein (Head protein Gp4)
SPAN1_BPP21 Spanin, inner membrane subunit (i-spanin) (Lysis protein Rz)
TERL_BPP21 terminase, large subunit gp2 (EC 3.1.-.-) (DNA-packaging protein) (Gene product 2) (gp2)
TERS_BPP21 Terminase, small subunit (Gp1)
HOLIN_BPP21 Antiholin
LYS_BPP21 Lysozyme (EC (Endolysin) (Lysis protein) (Muramidase)
VXIS_BPP21 Excisionase
VG05_BPP21 Head-tail preconnector protein GP5 (EC 3.4.21.-) (Putative peptidase GP5) [Cleaved into: Scaffold ...
VINT_BPP21 Integrase (EC 2.7.7.-) (EC 3.1.-.-)
W_BPP21 Head completion protein gp3 (Gene product 3) (gp3) (Head-stabilizing protein) (Head-tail joining ...
YG78_BPP21 Uncharacterized 13.5 kDa protein in GP7-GP8 intergenic region

14 entries

Bacillus phage phi105 (Bacteriophage phi-105)

YIM6_BPPH1 Putative uncharacterized immunity region protein 6
YIME_BPPH1 Uncharacterized immunity region protein 14
YIM4_BPPH1 Putative uncharacterized immunity region protein 4
YIM8_BPPH1 Putative uncharacterized immunity region protein 8
YIM5_BPPH1 Uncharacterized immunity region protein 5
IMMF_BPPH1 ImmF control region 10 kDa protein
RPC_BPPH1 Immunity repressor protein
YIMC_BPPH1 Uncharacterized immunity region protein 12
YIM2_BPPH1 Uncharacterized immunity region protein 2
YIM3_BPPH1 Uncharacterized immunity region protein 3
YIMB_BPPH1 Putative uncharacterized immunity region protein 11
YIM9_BPPH1 Putative uncharacterized immunity region protein 9
YIMD_BPPH1 Uncharacterized immunity region protein 13
YIMA_BPPH1 Putative uncharacterized immunity region protein 10

11 entries

Enterobacteria phage phi80 (Bacteriophage phi-80)

CAPSD_BPPH8 Major capsid protein (Gene product 5) (gp5) (Gene product E) (gpE) (Major head protein)
COR_BPPH8 Adsorption-inhibiting cor protein
REGN_BPPH8 Probable regulatory protein N
RPC1_BPPH8 Repressor protein CI
RPC2_BPPH8 Regulatory protein CII
VG15_BPPH8 Replication protein 15
VG14_BPPH8 Replication protein 14
VG40_BPPH8 Protein 40A
VG30_BPPH8 Gene 30 protein
VXIS_BPPH8 Excisionase
VINT_BPPH8 Integrase (EC 2.7.7.-) (EC 3.1.-.-)

9 entries

Escherichia phage HK022 (Bacteriophage HK022)

REGQ_BPHK0 Antitermination protein
RCRO_BPHK0 8.4 kDa cro protein
RPC3_BPHK0 Regulatory protein CIII
RPC1_BPHK0 26 kDa repressor protein (Regulatory protein CI)
VINT_BPHK0 Integrase (EC 2.7.7.-) (EC 3.1.-.-)
VKIL_BPHK0 Protein kil
VNUN_BPHK0 Transcription termination factor nun
VXIS_BPHK0 Excisionase
YO48_BPHK0 Uncharacterized 5.8 kDa protein (ORF48)

8 entries

Enterobacteria phage H19B (Bacteriophage H19B)

LYS_BPH19 Lysozyme (EC (Endolysin) (Lysis protein) (Muramidase)
NINF_BPH19 Protein ninF
NING_BPH19 Protein ninG
NINE_BPH19 Protein ninE
NINH_BPH19 Protein ninH
REGQ_BPH19 Antitermination protein Q
STXB_BPH19 Shiga-like toxin 1 subunit B (SLT-1 B subunit) (SLT-1b) (SLT-Ib) (Verocytotoxin 1 subunit B) ...
STXA_BPH19 Shiga-like toxin 1 subunit A (SLT-1 A subunit) (SLT-1a) (SLT-Ia) (EC (Verocytotoxin 1 ...

7 entries

Enterobacteria phage 82 (Bacteriophage 82)

NINE_BP82 Protein ninE
RUSA_BP82 Crossover junction endodeoxyribonuclease rusA (EC (Holliday junction nuclease rusA) ...
YBCN_BP82 Uncharacterized protein in rusA 5'region (ORF151)
YBCO_BP82 Uncharacterized protein ybcO
REGQ_BP82 Antitermination protein Q
YLCH_BP82 Uncharacterized 3.7 kDa protein in rusA 5'region (ORF33)
YLCG_BP82 Uncharacterized protein in rusA 3'region (ORF45)

5 entries

Enterobacteria phage 434 (Bacteriophage 434)

RCRO_BP434 Regulatory protein cro (Antirepressor)
REXA_BP434 Protein rexA
RPC2_BP434 Regulatory protein CII
VINT_BP434 Integrase (EC 2.7.7.-) (EC 3.1.-.-)
VXIS_BP434 Excisionase

2 entries

Bacillus phage phi3T (Bacteriophage phi-3T)

MTBP_BPPHT Modification methylase Phi3TI (M.Phi3TI) (EC (Cytosine-specific methyltransferase Phi3TI)
TYSY_BPPHT Thymidylate synthase (TS) (TSase) (EC

2 entries

Enterobacteria phage HK97 (Bacteriophage HK97)

PRO_BPHK7 Prohead protease (GP4)
PORTL_BPHK7 Portal protein (GP3)

2 entries

Corynephage beta

DTX_CORBE Diphtheria toxin (DT) (NAD(+)--diphthamide ADP-ribosyltransferase) (EC [Cleaved into: ...
DTXH_CORBE Diphtheria toxin homolog CRM228 [Cleaved into: Diphtheria toxin homolog CRM228 fragment A; ...

2 entries

Enterobacteria phage PA-2 (Bacteriophage PA-2)

PORI_BPPA2 Outer membrane porin protein LC
LYS_BPPA2 Lysozyme (EC (Endolysin) (Lysis protein) (Muramidase)

1 entry

Bacillus phage SP02 (Bacteriophage SP02)

DPOL_BPSP2 DNA polymerase (EC (EC 3.1.11.-)

1 entry

Bacillus phage SPR (Bacteriophage SPR)

MTBS_BPSPR Modification methylase SPRI (M.SPRI) (EC (Cytosine-specific methyltransferase SPRI)

1 entry

Bacillus phage rho11s (Bacteriophage rho-11s)

MTBR_BPRH1 Modification methylase Rho11sI (M.Rho11sI) (EC (Bsu P11s) (Cytosine-specific ...

1 entry

Corynephage omega

DTX_COROM Diphtheria toxin (DT) (NAD(+)--diphthamide ADP-ribosyltransferase) (EC [Cleaved into: ...