Phi29virus

VIRION

Non-enveloped, head-tail structure. The prolate capsid is about 45 × 54 nm, with a T=3, Q=5 symmetry . The tail is non-contractile and has a collar with 12 appendages attached to the neck region that are important for host cell recognition and entry. The 55 capsid (head) fibers are not always present and may have been lost in some lab strains. They may enhance the attachment of the virions onto the host cell wall.

GENOME

Linear, dsDNA genome of about 16 to 20 kb encoding between 20 and 30 genes, with a terminal protein covalently attached at the 5' end.

GENE EXPRESSION

REPLICATION

CYTOPLASMIC

  1. Adsorption: the phage attaches to target cell through its tail fibers.
  2. Ejection by short tail system: viral DNA is injected in host cell periplasm.
  3. Transcription and translation of early genes
  4. Replication of genomic DNA by strand displacement by the viral DNA polymerase, formation of viral genome concatemers.
  5. Transcription and translation of late genes
  6. Assembly of empty procapsids and viral genome packaging.
  7. Mature virions are released from the cell by lysis.

Matching UniProtKB/Swiss-Prot entries

85 entries grouped by strain (browse by keywords)

All proteins are shown (view only 74 complete proteome entries)

24 entries

Bacillus phage phi29 (Bacteriophage phi-29) reference strain

Select_allDeselect_all
CAPSD_BPPH2 Major capsid protein (Gene product 8) (gp8) (Major head protein) (Protein p8)
CAPSF_BPPH2 Capsid fiber protein (Gene product 8.5) (gp8.5) (Head fiber protein) (Protein p8.5)
FIB12_BPPH2 Pre-neck appendage protein (Gene product 12) (gp12) (NP1) (Protein p12) [Cleaved into: gp12*]
DIT9_BPPH2 Tail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9)
DPOL_BPPH2 DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
ENLYS_BPPH2 Endolysin (EC 3.2.1.17) (Gene product 15) (gp15) (Lysozyme) (Morphogenesis protein 2) (Muramidase) ...
GP17_BPPH2 DNA replication protein 17 (Gene product 17) (gp17) (Protein p17)
GP168_BPPH2 Gene product 16.8 (gp16.8) (Protein p16.8)
GP1_BPPH2 DNA replication protein 1 (Gene product 1) (gp1)
GP13_BPPH2 Morphogenesis protein 1 (Gene product 13) (gp13) (Protein p13) [Includes: Lysozyme-like glycosidase ...
GP166_BPPH2 Gene product 16.6 (gp16.6) (Protein p16.6)
GP167_BPPH2 DNA replication protein 16.7 (Gene product 16.7) (gp16.7) (Protein p16.7)
GP169_BPPH2 Gene product 16.9 (gp16.9) (Protein p16.9)
GP55_BPPH2 Gene product 5.5 (gp5.5) (Gene product 5B) (gp5B) (Protein p5.5)
NP_BPPH2 Histone-like protein p6 (Double-stranded DNA-binding protein p6) (Gene product 6) (gp6) ...
PORTL_BPPH2 Portal protein (Connector protein) (Gene product 10) (gp10) (Gene product 19) (gp19) (Head-to-tail ...
SCAF_BPPH2 Capsid assembly scaffolding protein (Gene product 7) (gp7) (Head morphogenesis protein) (Protein p7) ...
TERM_BPPH2 Primer terminal protein (TP) (DNA terminal protein) (Gene product 3) (gp3) (Protein p3) (Terminal ...
TF4_BPPH2 Late genes activator p4 (Gene product 4) (gp4) (Protein p4)
HOLIN_BPPH2 Antiholin (Gene product 14) (gp14) (Lysis inhibitor 14-131) (Protein p14) [Includes: Holin (Lysis ...
P56_BPPH2 Protein p56
PKG16_BPPH2 DNA packaging protein (ATPase gp16) (EC 3.6.4.-) (Gene product 16) (gp16) (Protein p16)
SSB_BPPH2 Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)
TUB11_BPPH2 Proximal tail tube connector protein (Gene product 11) (gp11) (Lower collar protein) (Protein p11)

4 entries

Bacillus phage Nf (Bacteriophage Nf) reference strain

Select_allDeselect_all
DIT9_BPNF Tail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9) (Tail protein)
DPOL_BPNF DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
NP_BPNF Double-stranded DNA-binding protein (Gene product 6) (gp6) (Nucleoid-associated protein p6) (Protein ...
SSB_BPNF Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)

3 entries

Bacillus phage GA-1 (Bacteriophage GA-1) reference strain

Select_allDeselect_all
CAPSD_BPGA1 Major capsid protein (Gene product 8) (gp8) (Major head protein)
P56_BPGA1 Protein p56
SSB_BPGA1 Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)

26 entries

Bacillus phage PZA (Bacteriophage PZA)

Select_allDeselect_all
CAPSD_BPPZA Major capsid protein (Gene product 8) (gp8) (Major head protein) (Protein p8)
CAPSF_BPPZA Capsid fiber protein (Gene product 8.5) (gp8.5) (Head fiber protein) (Protein p8.5)
DIT9_BPPZA Tail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9)
DPOL_BPPZA DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
ENLYS_BPPZA Endolysin (EC 3.2.1.17) (Gene product 15) (gp15) (Lysozyme) (Morphogenesis protein 2) (Muramidase) ...
FIB12_BPPZA Preneck appendage protein (Gene product 12) (gp12) (Protein p12) [Cleaved into: gp12*]
GP55_BPPZA Gene product 5B (gp5B) (Protein p5B)
GP13_BPPZA Morphogenesis protein 1 (Gene product 13) (gp13) (Protein p13) [Includes: Lysozyme-like glycosidase ...
GP165_BPPZA Gene product 16.5 (gp16.5) (Early protein GP16.5) (Protein p16.5)
GP166_BPPZA Gene product 16.6 (gp16.6) (Protein p16.6)
GP17_BPPZA DNA replication protein 17 (Gene product 17) (gp17) (Protein p17)
GP167_BPPZA DNA replication protein 16.7 (Gene product 16.7) (gp16.7) (Protein p16.7)
GP169_BPPZA Gene product 16.9 (gp16.9) (Protein p16.9)
GP1_BPPZA DNA replication protein 1 (Gene product 1C) (gp1C)
GP168_BPPZA Gene product 16.8 (gp16.8) (Protein p16.8)
NP_BPPZA Histone-like protein p6 (Double-stranded DNA-binding protein) (Double-stranded DNA-binding protein ...
PORTL_BPPZA Portal protein (Connector protein) (Gene product 10) (gp10) (Gene product 19) (gp19) (Head-to-tail ...
PKG16_BPPZA DNA packaging protein (ATPase gp16) (EC 3.6.4.-) (Gene product 16) (gp16) (Protein p16)
SCAF_BPPZA Capsid assembly scaffolding protein (Gene product 7) (gp7) (Head morphogenesis protein) (Protein p7) ...
TERM_BPPZA DNA terminal protein (Gene product 3) (gp3) (Protein p3)
TF4_BPPZA Late genes activator p4 (Gene product 4) (gp4) (Protein p4)
HOLIN_BPPZA Antiholin (Gene product 14) (gp14) (Lysis inhibitor 14-131) (Protein p14) [Includes: Holin (Lysis ...
P56_BPPZA Protein p56
SSB_BPPZA Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)
TUB11_BPPZA Proximal tail tube connector protein (Gene product 11) (gp11) (Lower collar protein) (Protein p11)
VG1A_BPPZA Early protein GP1A

1 entry

Bacillus phage phi29 (Bacteriophage phi-29)

GP165_BPPH2 Gene product 16.5 (gp16.5) (Protein p16.5)

17 entries

Bacillus phage B103 (Bacteriophage B103)

Select_allDeselect_all
CAPSD_BPB03 Major capsid protein (Gene product 8) (gp8) (Major head protein) (Protein p8)
CAPSF_BPB03 Capsid fiber protein (Gene product 8.5) (gp8.5) (Head fiber protein) (Protein p8.5)
DIT9_BPB03 Tail knob protein gp9 (Distal tube protein) (Gene product 9) (gp9) (Protein p9)
DPOL_BPB03 DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)
ENLYS_BPB03 Endolysin (EC 3.2.1.17) (Gene product 15) (gp15) (Lysozyme) (Morphogenesis protein 2) (Muramidase) ...
FIB12_BPB03 Pre-neck appendage protein (Gene product 12) (gp12) (Late protein GP12) (NP1) (Protein p12)
NP_BPB03 Histone-like protein p6 (Double-stranded DNA-binding protein) (Double-stranded DNA-binding protein ...
PORTL_BPB03 Portal protein (Gene product 10) (gp10) (Head-to-tail connector) (Upper collar protein)
SCAF_BPB03 Capsid assembly scaffolding protein (Gene product 7) (gp7) (Head morphogenesis protein) (Protein p7) ...
TERM_BPB03 DNA terminal protein (Gene product 3) (gp3) (Protein p3)
HOLIN_BPB03 Antiholin (Gene product 14) (gp14) (Protein p14) [Includes: Holin]
PKG16_BPB03 DNA packaging protein (ATPase gp16) (EC 3.6.4.-) (Gene product 16) (gp16) (Protein p16)
SSB_BPB03 Single-stranded DNA-binding protein (SSB) (Gene product 5) (gp5) (Protein p5)
TUB11_BPB03 Proximal tail tube connector protein (Gene product 11) (gp11) (Lower collar protein) (Protein p11)
VG17_BPB03 Early protein GP17
VG13_BPB03 Morphogenesis protein 1 (Late protein GP13) [Includes: Lysozyme-like glycosidase (EC 3.2.1.-); ...
VG4_BPB03 Late genes activator (Early protein GP4)

3 entries

Bacillus phage Nf (Bacteriophage Nf)

Select_allDeselect_all
TERM_BPNF DNA terminal protein (Gene product 3) (gp3) (Protein p3)
VG85_BPNF Head fiber protein (Late protein GP8.5)
VG4_BPNF Late genes activator (Early protein GP4) (GPF)

6 entries

Bacillus phage phi15 (Bacteriophage phi-15)

Select_allDeselect_all
GP168_BPPH5 Gene product 16.8 (gp16.8) (Protein p16.8)
GP166_BPPH5 Gene product 16.6 (gp16.6) (Protein p16.6)
GP165_BPPH5 Gene product 16.5 (gp16.5) (Early protein GP16.5) (Protein p16.5)
GP167_BPPH5 DNA replication protein 16.7 (Gene product 16.7) (gp16.7) (Protein p16.7)
GP169_BPPH5 Gene product 16.9 (gp16.9) (Protein p16.9)
GP17_BPPH5 DNA replication protein 17 (Gene product 17) (gp17) (Protein p17)

1 entry

Bacillus phage M2 (Bacteriophage M2)

DPOL_BPM2 DNA polymerase (EC 2.7.7.7) (EC 3.1.11.-) (Gene product 2) (gp2) (Protein p2)