Benyvirus

VIRION

Non-enveloped, rod shaped about 85-390 nm in length and 20 nm in diameter. The right-handed helix with a pitch of 2.6 nm has an axial repeat of four turns, involving 49 capsid subunits. Each capsid protein covers four nucleotides on the genomic RNA.

GENOME

Segmented, linear, ssRNA(+) genome. The four to five segments are 1.3 to 6.7 kb in size. The genomic RNA are capped, and polyadenylated.

GENE EXPRESSION

Genomic RNAs serve as messenger RNA. Subgenomic RNAs are synthesized during replication for segments 2 and 3. Suppression of termination on segment 2 produces the 75k protein. Leaky scanning allows expression of the movement proteins TGB2 and TGB3.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce the two proteins necessary for RNA synthesis (replication and transcription).
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Expression of the subgenomic RNAs (sgRNAs).
  7. Virus assembly, each segment is encapsidated.
  8. Viral TGB movement proteins probably mediate virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

The cysteine-rich protein of beet necrotic yellow vein virus and tobacco rattle virus act as suppressor of RNA silencing in roots, but not in leaves .

Matching UniProtKB/Swiss-Prot entries

12 entries grouped by protein (browse by keywords)

All proteins are shown (view only 9 complete proteome entries)

1 entry

Capsid readthrough protein (CP-RT)

CAPSD_BNYVS
Beet necrotic yellow vein virus (isolate Japan/S) (BNYVV) reference strain

1 entry

Protein P25 (25kDa protein)

P25_BNYVS
Beet necrotic yellow vein virus (isolate Japan/S) (BNYVV) reference strain

1 entry

Protein P26 (26kDa protein)

P26_BNYVS
Beet necrotic yellow vein virus (isolate Japan/S) (BNYVV) reference strain

1 entry

31 kDa protein (31k protein) (p31)

P31_BNYVS
Beet necrotic yellow vein virus (isolate Japan/S) (BNYVV) reference strain

1 entry

Replicase (237 kDa protein)

RDRP_BNYVS
Beet necrotic yellow vein virus (isolate Japan/S) (BNYVV) reference strain

1 entry

Movement protein TGB1 (P42) (Triple gene block 1 protein) (TGBp1)

TGB1_BNYVS
Beet necrotic yellow vein virus (isolate Japan/S) (BNYVV) reference strain

1 entry

Movement protein TGB2 (13 kDa protein) (P13) (Triple gene block 2 protein) (TGBp2)

TGB2_BNYVS
Beet necrotic yellow vein virus (isolate Japan/S) (BNYVV) reference strain

1 entry

Movement protein TGB3 (15 kDa protein) (P15) (Triple gene block 3 protein) (TGBp3)

TGB3_BNYVS
Beet necrotic yellow vein virus (isolate Japan/S) (BNYVV) reference strain

1 entry

Probable suppressor of RNA silencing (14kD cysteine rich protein) (P14)

VSR_BNYVS
Beet necrotic yellow vein virus (isolate Japan/S) (BNYVV) reference strain

1 entry

RNA-3 uncharacterized 11.6 kDa protein

Y12K_BNYVG
Beet necrotic yellow vein mosaic virus (isolate Yugoslavia/G1) (BNYVV)

1 entry

RNA-3 uncharacterized 24.7 kDa protein

Y25K_BNYVF
Beet necrotic yellow vein mosaic virus (isolate France/F2) (BNYVV)

1 entry

RNA-4 uncharacterized 31.9 kDa protein

Y32K_BNYVG
Beet necrotic yellow vein mosaic virus (isolate Yugoslavia/G1) (BNYVV)