Secoviridae

VIRION

Non-enveloped, 25-30 nm in diameter, T=pseudo3 icosahedral capsid. The three jell rolls, which are characteristic of picornavirales capsid proteins (CP), can be present in one large CP with 3 jelly rolls domains, two CP (one large with two jelly rolls domains and one small a single domain), or three CP.

GENOME

Segmented, bipartite linear ssRNA(+) genome composed of RNA-1=6-8 kb and RNA-2=4-7 kb. Each genomic segment has a VPg linked to its 5' end and a 3' poly(A) tract.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and mRNA.
RNA-1 and RNA-2 are translated into two polyproteins, which are then processed into functional proteins. RNA-1 encodes proteins necessary for replication, while RNA-2 encodes one or two capsid proteins and product(s) involved in cell-to-cell movement.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. Synthesis and proteolytic cleavage of the replicase polyprotein RNA-1.
  4. Replication occurs in viral factories made of membrane vesicles derived from the ER. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. Assembly of new virus particles.
  7. Movement protein allows cell-to-cell movement.

Matching UniProtKB/Swiss-Prot entries

52 entries grouped by strain (browse by keywords)

All proteins are shown (view only 41 complete proteome entries)

4 entries

Tomato ringspot virus (isolate raspberry) (ToRSV) reference strain

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POL1_TORVR RNA1 polyprotein (P1) [Cleaved into: Protein X1; Protein X2; Putative ATP-dependent helicase (EC ...
POL2_TORVR RNA2 polyprotein (P2) [Cleaved into: Protein X3; Protein X4; Movement protein (MP); Coat protein ...
YR21_TORVR Uncharacterized protein in RNA2
YR22_TORVR Uncharacterized protein in RNA2

3 entries

Tomato torrado virus (isolate Solanum lycopersicum/Spain/PRIToTV0301/-) (ToTV) reference strain

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ORF1_TOTV Uncharacterized protein ORF1
POL2_TOTV RNA2 polyprotein [Cleaved into: Movement protein; Capsid protein VP35; Capsid protein VP26; Capsid ...
POL1_TOTV RNA1 polyprotein [Cleaved into: Protease-cofactor; Putative helicase (EC 3.6.4.-); Picornain 3C-like ...

2 entries

Broad bean wilt virus 1 (strain Spinach/United States/ATCC PV-132/1963) (BBWV-1) reference strain

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POL2_BBWVS RNA2 polyprotein (Genome polyprotein M) [Cleaved into: Movement protein (MP); Large capsid protein ...
POL1_BBWVS RNA1 polyprotein (Genome polyprotein B) [Cleaved into: Protease cofactor; Putative helicase (EC ...

2 entries

Cherry rasp leaf virus (isolate Potato/United States) (CRLV) reference strain

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POL2_CRLVP RNA2 polyprotein (P2) [Cleaved into: Movement protein; Capsid protein VP25; Capsid protein VP20; ...
POL1_CRLVP RNA1 polyprotein (Genome polyprotein B) (P1) [Cleaved into: Protease cofactor; Putative helicase (EC ...

2 entries

Cowpea mosaic virus (strain SB) (CPMV) reference strain

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POL2_CPMVS RNA2 polyprotein (Genome polyprotein M) (P2) [Cleaved into: Movement protein (MP); Large coat ...
POL1_CPMVS RNA1 polyprotein (Genome polyprotein B) (P1) [Cleaved into: Protease cofactor (32 kDa protein); ...

2 entries

Satsuma dwarf virus (isolate Satsuma mandarin/Japan/S-58/1977) (SDV) reference strain

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POL2_SDVS5 RNA2 polyprotein (P2) [Cleaved into: Movement protein (MP); Large capsid protein (LCP); Small capsid ...
POL1_SDVS5 RNA1 polyprotein (P1) [Cleaved into: Putative helicase (EC 3.6.4.-) (Putative NTP-binding protein); ...

1 entry

Parsnip yellow fleck virus (isolate P-121) (PYFV) reference strain

POLG_PYFV1 Genome polyprotein [Cleaved into: Putative leader protein; Capsid protein 1 (CP-1) (22.5 kDa ...

1 entry

Rice tungro spherical virus (strain A) (RTSV) (Rice tungro spherical waikavirus) reference strain

POLG_RTSVA Genome polyprotein [Cleaved into: Putative leader protein; Capsid protein 1 (CP-1) (22.5 kDa ...

3 entries

Beet ringspot virus (BRSV) (Tomato black ring virus (strain S))

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POL1_BRSV RNA1 polyprotein (P1) [Cleaved into: P1A protein (1A) (Protease cofactor); Putative ATP-dependent ...
POL2_BRSV RNA2 polyprotein (P2) [Cleaved into: Protein 2A (P2A); Movement protein (2B-MP); Coat protein ...
VS48_BRSV Satellite RNA 48 kDa protein

3 entries

Grapevine fanleaf virus (GFLV)

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POL2_GFLV RNA2 polyprotein (P2) [Cleaved into: Protein 2A (P2A); Movement protein (2B-MP); Coat protein ...
POL1_GFLV RNA1 polyprotein (P1) [Cleaved into: P1A protein (1A) (Protease cofactor); Putative ATP-dependent ...
VP3_GFLV Protein P3

2 entries

Arabis mosaic virus (isolate NW) (ArMV)

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POL1_ARMVN RNA1 polyprotein (P1) [Cleaved into: P1A protein (1A) (Protease cofactor); Putative ATP-dependent ...
POL2_ARMVN RNA2 polyprotein (P2) [Cleaved into: Protein 2A (P2A); Movement protein (2B-MP); Coat protein ...

2 entries

Bean-pod mottle virus (strain Kentucky G7) (BPMV)

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POL1_BPMV RNA1 polyprotein (Genome polyprotein B) (P1) [Cleaved into: Protease cofactor (32 kDa protein); ...
POL2_BPMV RNA2 polyprotein (Genome polyprotein M) (P2) [Cleaved into: Movement protein (MP); Large coat ...

2 entries

Blackcurrant reversion association virus (BRAV)

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POL2_BRAV RNA2 polyprotein (P2) [Cleaved into: Protein 2A; Movement protein (MP); Coat protein (CP)]
POL1_BRAV RNA1 polyprotein (P1) [Cleaved into: Protein X1; Protein X2; Putative ATP-dependent helicase (EC ...

2 entries

Cowpea severe mosaic virus (strain DG) (CPSMV)

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POL2_CPSMV RNA2 polyprotein (Genome polyprotein M) (P2) [Cleaved into: Movement protein (MP); Large coat ...
POL1_CPSMV RNA1 polyprotein (Genome polyprotein B) (P1) [Cleaved into: Protease cofactor (32 kDa protein); ...

2 entries

Cycas necrotic stunt virus (CNSV)

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POL2_CNSV RNA2 polyprotein (P2) [Cleaved into: Protein 2A (P2A); Movement protein (2B-MP); Coat protein ...
POL1_CNSV RNA1 polyprotein (P1) [Cleaved into: P1A protein (1A) (Protease cofactor); Putative ATP-dependent ...

2 entries

Grapevine chrome mosaic virus (GCMV) (Hungarian grapevine chrome mosaic virus)

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POL2_GCMV RNA2 polyprotein (P2) [Cleaved into: Protein 2A (P2A); Movement protein (2B-MP); Coat protein ...
POL1_GCMV RNA1 polyprotein (P1) [Cleaved into: P1A protein (1A) (Protease cofactor); Putative ATP-dependent ...

2 entries

Raspberry ringspot virus (strain cherry) (RpRSV)

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POL1_RRVC RNA1 polyprotein (P1) [Cleaved into: P1A protein (1A) (Protease cofactor); Putative ATP-dependent ...
POL2_RRVC RNA2 polyprotein (P2) [Cleaved into: Protein 2A (P2A); Movement protein (2B-MP); Coat protein ...

2 entries

Red clover mottle virus (RCMV)

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POL2_RCMV RNA2 polyprotein (Genome polyprotein M) (P2) [Cleaved into: Movement protein (MP); Large coat ...
POL1_RCMV RNA1 polyprotein (Genome polyprotein B) (P1) [Cleaved into: Protease cofactor (32 kDa protein); ...

2 entries

Tobacco ringspot virus (TobRV) (TRSV)

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CAPSD_TRSV Capsid protein (Coat protein)
POL2_TRSV RNA2 polyprotein (P2) [Cleaved into: Protein 2A (P2A); Movement protein (2B-MP); Coat protein ...

1 entry

Andean potato mottle virus (APMV)

POL2_APMV RNA2 polyprotein (Genome polyprotein M) (P2) [Cleaved into: Movement protein (MP); Large coat ...

1 entry

Arabis mosaic virus (ArMV)

VP3_ARMV Protein P3

1 entry

Arabis mosaic virus (isolate Syrah) (ArMV)

POL2_ARMVS RNA2 polyprotein (P2) [Cleaved into: Protein 2A (P2A); Movement protein (2B-MP); Coat protein ...

1 entry

Grapevine fanleaf virus (isolate NW) (GFLV)

POL2_GFLVN RNA2 polyprotein (P2) [Cleaved into: Protein 2A (P2A); Movement protein (2B-MP); Coat protein ...

1 entry

Raspberry ringspot virus (strain S) (RpRSV)

POL2_RRVS RNA2 polyprotein (P2) [Cleaved into: Protein 2A (P2A); Movement protein (2B-MP); Coat protein ...

1 entry

Rice tungro spherical virus (strain Vt6) (RTSV) (Rice tungro spherical waikavirus)

POLG_RTSVT Genome polyprotein [Cleaved into: Putative leader protein; Capsid protein 1 (CP-1) (22.5 kDa ...

1 entry

Tobacco ringspot virus (strain Bud Blight) (TobRV) (TRSV)

POL1_TRSVB RNA1 polyprotein (P1) [Cleaved into: P1A protein (1A) (Protease cofactor); Putative ATP-dependent ...

1 entry

Tomato black ring virus (strain C) (TBRV)

VS48_TBRVC Satellite RNA 48 kDa protein

1 entry

Tomato black ring virus (strain E) (TBRV)

VS48_TBRVE Satellite RNA 48 kDa protein

1 entry

Tomato black ring virus (strain L) (TBRV)

VS48_TBRVL Satellite RNA 48 kDa protein

1 entry

Tomato black ring virus (strain MJ) (TBRV)

POL1_TBRVM RNA1 polyprotein (P1) [Cleaved into: P1A protein (1A) (protease cofactor); Putative ATP-dependent ...