Virgaviridae

VIRION

Non-enveloped, rigid helical rods with a helical symmetry, about 20-25 nm in diameter with a central “canal”. There may be one, two or three segments depending on the considered genus.

GENOME

Monopartite or segmented (depending on the considered genus), linear, ssRNA(+) genome. Genomic RNA displays a tRNA-like structure in 3', but no poly-A tail, except for some hordeiviruses which have an internal poly-A tract between the coding sequence and the tRNA-like structure.

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and viral messenger RNA. The RNA-1 5'-proximal ORFs are directly translated to produce the viral constituents of the replicase complex. RdRp is translated through suppression of termination at the end of ORF1 in most genera. The downstream genes encoding the movement protein(s), viral suppressor of RNA silencing (VSR) and capsid proteins are usually translated from subgenomic RNAs.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the host cell.
  2. Uncoating, and release of the viral genomic RNA into the cytoplasm.
  3. The viral RNA is translated to produce the two proteins necessary for RNA synthesis (replication and transcription).
  4. Replication takes place in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
  5. The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
  6. The RdRp recognizes internal subgenomic promoters on the negative-sense RNA to transcribe the 3’co-terminal subgenomic RNAs that will generate the capsid protein, movement protein(s) and viral suppressor of RNA silencing (VSR).
  7. Virus assembly in the cytoplasm. Each segment (if multipartite) is encapsidated.
  8. Viral movement protein(s) probably mediate virion cell-to-cell transfer.

Host-virus interaction

Suppression of RNA silencing

Soilborne wheat mosaic virus (furovirus) 19K protein suppresses RNA silencing .

P15 of peanut clump virus (pecluvirus) suppresses RNA silencing .

Barley stripe mosaic virus (hordeivirus)gamma-b protein suppresses RNA silencing .

Tobacco mosaic tobamovirus (tobamovirus)126-kDa small replicase subunit suppresses RNA silencing .

Tobacco rattle virus (tobravirus)16K protein suppresses RNA silencing .

Matching UniProtKB/Swiss-Prot entries

126 entries grouped by strain (browse by keywords)

All proteins are shown (view only 86 complete proteome entries)

7 entries

Barley stripe mosaic virus (BSMV) reference strain

Select_allDeselect_all
TGB1_BSMV Movement protein TGB1 (58 kDa protein) (Beta-B protein) (Triple gene block 1 protein) (TGBp1)
TGB3_BSMV Movement protein TGB3 (17 kDa protein) (Beta-C protein) (Triple gene block 3 protein) (TGBp3)
VSR_BSMV Suppressor of RNA silencing (Gamma-B protein)
ALPHA_BSMV Alpha-A protein [Includes: Methyltransferase (EC 2.1.1.-) (EC 2.7.7.-); NTPase/helicase (EC ...
CAPSD_BSMV Capsid protein (Beta-A protein) (Coat protein)
RDRP_BSMV RNA-directed RNA polymerase (EC 2.7.7.48) (Gamma-A protein)
TGB2_BSMV Movement protein TGB2 (14 kDa protein) (Beta-D protein) (Triple gene block 2 protein) (TGBp2) ...

7 entries

Peanut clump virus (isolate 87/TGTA2) (PCV) reference strain

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TGB2_PCV87 Movement protein TGB2 (P14) (Triple gene block 2 protein) (TGBp2)
TGB1_PCV87 Movement protein TGB1 (P51) (Triple gene block 1 protein) (TGBp1)
TGB3_PCV87 Movement protein TGB3 (P17) (Triple gene block 3 protein) (TGBp3)
VSR_PCV87 Suppressor of RNA silencing (15kD cysteine rich protein) (P15)
CAPSD_PCV87 Capsid protein (Coat protein) (P23)
P39_PCV87 Protein P39
RDRP_PCV87 Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (RNA-directed RNA ...

7 entries

Potato mop-top virus (isolate Potato/Sweden/Sw) (PMTV) reference strain

Select_allDeselect_all
TGB1_PMTVS Movement protein TGB1 (P51) (Triple gene block 1 protein) (TGBp1)
VSR_PMTVS Suppressor of RNA silencing (8kD cysteine rich protein) (P8)
CAPSD_PMTVS Capsid protein (Coat protein)
CPRT_PMTVS 91 kDa readthrough protein (CP-RT)
RDRP_PMTVS Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (RNA-directed RNA ...
TGB2_PMTVS Movement protein TGB2 (P14) (Triple gene block 2 protein) (TGBp2)
TGB3_PMTVS Movement protein TGB3 (P21) (Triple gene block 3 protein) (TGBp3)

6 entries

Tobacco rattle virus (isolate PpK20) (TRV) reference strain

Select_allDeselect_all
VSR_TRVPP Suppressor of RNA silencing (16kD cysteine rich protein) (P16)
CAPSD_TRVPP Capsid protein (Coat protein) (P23)
P40_TRVPP 40 kDa protein
P32_TRVPP 32 kDa protein
MVP_TRVPP Movement protein (29 kDa protein) (Cell-to-cell transport protein) (P1a)
RDRP_TRVPP Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (194 kDa protein) ...

5 entries

Soil-borne wheat mosaic virus (strain United States/Nebraska/1981) (SBWMV) reference strain

Select_allDeselect_all
VSR_SBWMN Suppressor of RNA silencing (19kD cysteine rich protein) (P19)
CAPSD_SBWMN Capsid protein (Coat protein) (P19)
CPRT_SBWMN 84 kDa readthrough protein (CP-RT)
MVP_SBWMN Movement protein (37 kDa protein) (Cell-to-cell transport protein)
RDRP_SBWMN Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (209 kDa readthrough ...

3 entries

Cucumber green mottle mosaic virus (strain watermelon SH) (CGMMV) reference strain

Select_allDeselect_all
CAPSD_CGMVS Capsid protein (Coat protein)
MVP_CGMVS Movement protein (28.8 kDa protein) (Cell-to-cell transport protein)
RDRP_CGMVS Replicase large subunit (EC 2.7.7.48) (186 kDa protein) [Cleaved into: Replicase small subunit (EC ...

3 entries

Sunn-hemp mosaic virus (SHMV) (TMV strain cowpea) reference strain

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CAPSD_SHMV Capsid protein (Coat protein)
MVP_SHMV Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_SHMV Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

1 entry

Tobacco mosaic virus (strain OM) (TMV) reference strain

RDRP_TMVOM Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Tobacco mosaic virus (strain vulgare) (TMV) (Tobacco mosaic virus (strain U1)) reference strain

Select_allDeselect_all
CAPSD_TMV Capsid protein (Coat protein)
MVP_TMV Movement protein (30 kDa protein) (Cell-to-cell transport protein) [Cleaved into: 27.9 kDa protein; ...
RDRP_TMV Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Turnip vein-clearing virus (TVCV) reference strain

Select_allDeselect_all
CAPSD_TVCV Capsid protein (Coat protein)
MVP_TVCV Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_TVCV Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Odontoglossum ringspot virus (isolate Korean Cy) (ORSV-Cy)

Select_allDeselect_all
CAPSD_ORSVC Capsid protein (Coat protein)
MVP_ORSVC Movement protein (33.4 kDa protein) (Cell-to-cell transport protein)
RDRP_ORSVC Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Odontoglossum ringspot virus (isolate Singapore 1) (ORSV)

Select_allDeselect_all
CAPSD_ORSVS Capsid protein (Coat protein)
MVP_ORSVS Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_ORSVS Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Pea early browning virus

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V23K_PEBV 23 kDa protein
2B_PEBV Protein 2b (29.6 kDa protein)
COAT_PEBV Coat protein (Capsid protein)

3 entries

Pepper mild mottle virus (strain Japan) (PMMV-J)

Select_allDeselect_all
CAPSD_PMMVJ Capsid protein (Coat protein)
MVP_PMMVJ Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_PMMVJ Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Pepper mild mottle virus (strain Spain) (PMMV-S)

Select_allDeselect_all
CAPSD_PMMVS Capsid protein (Coat protein)
MVP_PMMVS Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_PMMVS Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Tobacco mild green mosaic virus (TMGMV) (TMV strain U2)

Select_allDeselect_all
CAPSD_TMGMV Capsid protein (Coat protein)
MVP_TMGMV Movement protein (28.5 kDa protein) (Cell-to-cell transport protein)
RDRP_TMGMV Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Tobacco mosaic virus (strain B935A) (TMV)

Select_allDeselect_all
CAPSD_TMVB Capsid protein (Coat protein)
MVP_TMVB Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_TMVB Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Tobacco mosaic virus (strain Korean NC 82) (TMV)

Select_allDeselect_all
CAPSD_TMVKR Capsid protein (Coat protein)
MVP_TMVKR Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_TMVKR Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

2 entries

Tobacco mosaic virus (strain OM) (TMV)

Select_allDeselect_all
CAPSD_TMVOM Capsid protein (Coat protein)
MVP_TMVOM Movement protein (30 kDa protein) (Cell-to-cell transport protein) [Cleaved into: 27.9 kDa protein; ...

3 entries

Tobacco mosaic virus (strain Rakkyo) (TMV-R)

Select_allDeselect_all
CAPSD_TMVRA Capsid protein (Coat protein)
MVP_TMVRA Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_TMVRA Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Tobacco rattle virus (strain PLB)

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V16K_TRVPL 16 kDa protein
V13K_TRVPL 16 kDa protein
COAT_TRVPL Coat protein (Capsid protein)

3 entries

Tobacco rattle virus (strain PSG)

Select_allDeselect_all
V16K_TRVPS 16 kDa protein
V29K_TRVPS 29 kDa protein
COAT_TRVPS Coat protein (Capsid protein)

3 entries

Tobacco rattle virus (strain SYM)

Select_allDeselect_all
V16K_TRVSY 16 kDa protein
V29K_TRVSY 29 kDa protein
194K_TRVSY Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (194 kDa protein) ...

3 entries

Tobacco rattle virus (strain TCM)

Select_allDeselect_all
V16K_TRVTC 16 kDa protein
2B_TRVTC Protein 2b (29.1 kDa protein)
COAT_TRVTC Coat protein (Capsid protein)

3 entries

Tobamovirus Ob

Select_allDeselect_all
CAPSD_TMOB Capsid protein (Coat protein)
MVP_TMOB Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_TMOB Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Tomato mosaic virus (strain Kazakh K1) (ToMV) (TMV strain K1)

Select_allDeselect_all
CAPSD_TOMK1 Capsid protein (Coat protein)
MVP_TOMK1 Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_TOMK1 Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Tomato mosaic virus (strain Kazakh K2) (ToMV) (TMV strain K2)

Select_allDeselect_all
CAPSD_TOMK2 Capsid protein (Coat protein)
MVP_TOMK2 Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_TOMK2 Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Tomato mosaic virus (strain L) (ToMV) (TMV strain tomato)

Select_allDeselect_all
CAPSD_TOML Capsid protein (Coat protein)
MVP_TOML Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_TOML Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Tomato mosaic virus (strain S-1) (ToMV)

Select_allDeselect_all
CAPSD_TOMS1 Capsid protein (Coat protein)
MVP_TOMS1 Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_TOMS1 Replicase large subunit (EC 2.1.1.-) (EC 2.7.7.-) (EC 2.7.7.48) (EC 3.6.4.13) (183 kDa protein) ...

3 entries

Youcai mosaic virus (YoMV) (Oilseed rape mosaic virus)

Select_allDeselect_all
CAPSD_YOMV Capsid protein (Coat protein)
MVP_YOMV Movement protein (30 kDa protein) (Cell-to-cell transport protein)
RDRP_YOMV Replicase large subunit (EC 2.7.7.48) (182 kDa protein) [Cleaved into: Replicase small subunit (EC ...

2 entries

Cucumber green mottle mosaic virus (strain watermelon W) (CGMMV)

Select_allDeselect_all
CAPSD_CGMVW Capsid protein (Coat protein)
MVP_CGMVW Movement protein (28.8 kDa protein) (Cell-to-cell transport protein)

2 entries

Odontoglossum ringspot virus (isolate Japan) (ORSV)

Select_allDeselect_all
CAPSD_ORSVJ Capsid protein (Coat protein)
MVP_ORSVJ Movement protein (33.4 kDa protein) (Cell-to-cell transport protein)

2 entries

Ribgrass mosaic virus (RMV)

Select_allDeselect_all
CAPSD_RMV Capsid protein (Coat protein)
MVP_RMV Movement protein (30 kDa protein) (Cell-to-cell transport protein)

1 entry

Paprika mild mottle virus (PaMMV)

CAPSD_PMMV Capsid protein (Coat protein)

1 entry

Pepper mild mottle virus (strain Italian) (PMMV-I)

CAPSD_PMMVI Capsid protein (Coat protein)

1 entry

Pepper mild mottle virus (strain P0) (PMMV)

CAPSD_PMMV0 Capsid protein (Coat protein)

1 entry

Pepper mild mottle virus (strain P1) (PMMV)

CAPSD_PMMV1 Capsid protein (Coat protein)

1 entry

Pepper mild mottle virus (strain P2) (PMMV)

CAPSD_PMMV2 Capsid protein (Coat protein)

1 entry

Ribgrass mosaic virus (strain CAB) (RMV)

CAPSD_RMVCA Capsid protein (Coat protein)

1 entry

Ribgrass mosaic virus (strain Hr) (RMV) (TMV strain Holmes ribgrass)

CAPSD_RMVHR Capsid protein (Coat protein)

1 entry

Tobacco mosaic virus (strain 06) (TMV-06)

CAPSD_TMV06 Capsid protein (Coat protein)

1 entry

Tobacco mosaic virus (strain Dahlemense) (TMV)

CAPSD_TMVDA Capsid protein (Coat protein)

1 entry

Tobacco mosaic virus (strain ER) (TMV)

CAPSD_TMVER Capsid protein (Coat protein)

1 entry

Tobacco mosaic virus (strain Kokubu) (TMV)

CAPSD_TMVKO Capsid protein (Coat protein)

1 entry

Tobacco mosaic virus (strain O) (TMV)

CAPSD_TMVO Capsid protein (Coat protein)

1 entry

Tobacco rattle virus (strain CAM)

COAT_TRVCA Coat protein (Capsid protein)

1 entry

Tomato mosaic virus (strain Korean) (ToMV)

CAPSD_TOMKO Capsid protein (Coat protein)

1 entry

Tomato mosaic virus (strain LII) (ToMV)

MVP_TOML2 Movement protein (30 kDa protein) (Cell-to-cell transport protein)

1 entry

Tomato mosaic virus (strain LIIa) (ToMV)

MVP_TOMLA Movement protein (30 kDa protein) (Cell-to-cell transport protein)