Cryspovirus

VIRION

Non-enveloped icosahedral capsid, about 35-40 nm in diameter with a T=2* icosahedral symmetry . The two genomic segments are encapsidated separately.

GENOME

Segmented dsRNA linear genome: 2 segments encoding potentially for 2 proteins. Segments are about 2.1 kb each, total size about 4 kb.

GENE EXPRESSION

Each genomic segment is monocistronic.

REPLICATION

CYTOPLASMIC

  1. Virus penetrates into the cytoplasm.
  2. Transcription of the dsRNA genome by viral polymerase occurs inside the virion, so that dsRNA is never exposed to the cytoplasm. This plus-strand transcript is used as template for translation.
  3. (+)RNAs are encapsidated in virion particle, inside which they are transcribed to give RNA (-) molecules with which they become base-paired to produce dsRNA genomes.
  4. Mature are transmitted to new cell during cell division, sporogenesis or cell fusion.

Matching UniProtKB/Swiss-Prot entries

2 entries grouped by strain (browse by keywords)

2 entries

Cryptosporidium parvum virus 1 (strain KSU-1) reference strain

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CAPSD_CPVKS Capsid protein (CP) (Coat protein)
RDRP_CPVKS RNA-directed RNA polymerase (EC 2.7.7.48)