Enveloped, bullet shaped. 180 nm long and 75 nm wide. Certain plant rhabdoviruses are bacilliform in shape and almost twice the length.
Negative-stranded RNA linear genome, about 11-15 kb in size. Encodes for 5 to six proteins.
The viral RNA dependent RNA polymerase binds the encapsidated genome at the leader region, then sequentially transcribes each genes by recognizing start and stop signals flanking viral genes. mRNAs are capped and polyadenylated by the L protein during synthesis.
- Attachment of the viral G glycoproteins to host receptors
- Fusion of virus membrane with the vesicle membrane; ribonucleocapsid is released into the cytoplasm.
- Sequential transcription , viral mRNAs are capped and polyadenylated by polymerase stuttering in the cytoplasm.
- Replication presumably starts when enough nucleoprotein is present to encapsidate neo-synthetized antigenomes and genomes.
- The ribonucleocapsid can penetrate in neighboring cells through plasmodesmata transport
- The ribonucleocapsid binds to the matrix protein and the budding of particles occurs at a cell membrane, releasing new virions.