Actin-dependent inwards viral transport (kw:KW-1178)

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In a cell, structures in excess of 20nm require energy-dependent motility to travel through the cytosol. Therefore viruses with entire capsid or large genome entering the cytoplasm utilize molecular motors to move through the cytosol. The majority of viruses use microtubules but some have been described as using actin cytoskeleton.
Actin-dependent transport is induced by viral proteins that interact with actin and/or host cell motor proteins like myosins or that promotes actin polymerization/depolymerization reactions.

Matching UniProtKB/Swiss-Prot entries

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5 entries grouped by strain

1 entry

Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) reference strain

PROF_VACCW Profilin

1 entry

Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) reference strain

PROF_VAR67 Profilin

1 entry

Ectromelia virus (strain Moscow) (ECTV) (Mousepox virus)

PROF_ECTVM Profilin

1 entry

Vaccinia virus (strain Copenhagen) (VACV)

PROF_VACCC Profilin

1 entry

Variola virus

PROF_VARV Profilin