Eukaryotic host transcription shutoff by virus

Host RNA polymerase II (RNA pol-II) is the major enzyme responsible for transcription of mRNA from a DNA template strand.

transcription initiation modulation PolII regulation

Some viruses interfere with host RNA pol-II function. They may either mediate its ubiquitination and subsequent proteasomal degradation, or inhibit RNA pol-II phosphorylation thereby lowering its efficiency. They can as well interfere with initiation factors. Inhibiting host transcription eventually leads to shutoff of host proteins expression and gives viruses transcripts a competitive edge for access to the cellular translation machinery. Preventing the expression of host proteins is also a strategy to counteract the antiviral response.

Viruses inhibiting transcription:

Family Virus Viral protein Transcription inhibition strategy references
Herpesviridae HHV-1 ICP22 Counteracts CTD Ser-2 phosphorylation
Bunyaviridae Bunyamwera virus NSs Counteracts CTD Ser-2 phosphorylation
Orthomyxoviridae Influenza virus Polymerase PB1, PB2, PA RNA pol-II ubiquitination and proteasomal degradation
Papillomaviridae, alphapapillomavirus HPV16 E7 Inhibition of TBP
Picornaviridae Poliovirus 3C Cleavage of TBP
Bunyaviridae, Phlebovirus Rift valley fever virus NSs Downregulates TFIIH subunit p62
Herpesviridae Varicella virus IE63 Disruption of the transcriptional pre-initiation complex

Matching UniProtKB/Swiss-Prot entries

311 entries grouped by protein (browse by keywords)

All proteins are shown (view only 205 complete proteome entries)

Early E1A protein (Early E1A 32 kDa protein)

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E1A_ADE02Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2) reference strain
E1A_ADE05Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)

Transcriptional regulator ICP22 (Immediate-early protein IE68) (Infected cell protein 22) (ICP22)

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ICP22_HHV11Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) reference strain
ICP22_HHV2HHuman herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2) reference strain
ICP22_VZVDVaricella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3) reference strain

Transcriptional regulator ICP22 homolog (Immediate-early protein 63) (IE63) (Transcriptional regulator IE63)

ICP22_VZVOVaricella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)

Transcriptional regulator ICP22 homolog (Immediate-early protein 63) (IE63) (Transcriptional transactivator IE63)

Non-structural protein NS-S

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NSS_BUNYWBunyamwera virus (BUNV) reference strain
NSS_BUNL8Bunyavirus La Crosse (isolate Human/United States/L78/1978) reference strain
NSS_RVFVZRift valley fever virus (strain ZH-548 M12) (RVFV) reference strain

Non-structural protein S (NSs)

NSS_BUNGEBunyavirus germiston
NSS_BUNLCBunyavirus La Crosse
NSS_BUNSHBunyavirus snowshoe hare

Polymerase acidic protein (RNA-directed RNA polymerase subunit P2)

Select_all Deselect_all  
PA_I96A0Influenza A virus (strain A/Goose/Guangdong/1/1996 H5N1 genotype Gs/Gd) reference strain
PA_I34A1Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
PA_I80A2Influenza A virus (strain A/Seal/Massachusetts/1/1980 H7N7) reference strain
PA_I80A8Influenza A virus (strain A/Turkey/Minnesota/833/1980 H4N2) reference strain
PA_I60A0Influenza A virus (strain A/Ann Arbor/6/1960 H2N2)
PA_I75A0Influenza A virus (strain A/Beijing/39/1975 H3N2)

Polymerase acidic protein

PA_I77AAInfluenza A virus (strain A/Brazil/11/1978 H1N1)
PA_I18A0Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus ...
PA_I02A0Influenza A virus (strain A/Chicken/Brescia/1902 H7N7)
PA_I97A0Influenza A virus (strain A/Chicken/Hong Kong/220/1997 H5N1 genotype Gs/Gd)
PA_I02A2Influenza A virus (strain A/Chicken/Hong Kong/31.2/2002 H5N1 genotype X1)
PA_I01A3Influenza A virus (strain A/Chicken/Hong Kong/715.5/2001 H5N1 genotype E)
PA_I02A5Influenza A virus (strain A/Chicken/Hong Kong/96.1/2002 H5N1 genotype Y)
PA_I02A6Influenza A virus (strain A/Chicken/Hong Kong/YU22/2002 H5N1 genotype Z)
PA_I83A5Influenza A virus (strain A/Chicken/Pennsylvania/1/1983 H5N2)
PA_I59A0Influenza A virus (strain A/Chicken/Scotland/1959 H5N1)
PA_I85A3Influenza A virus (strain A/Chicken/Victoria/1/1985 H7N7)
PA_I83A1Influenza A virus (strain A/Chile/1/1983 H1N1)
PA_I96A3Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)
PA_I56A1Influenza A virus (strain A/Duck/Czechoslovakia/1956 H4N6)
PA_I56A2Influenza A virus (strain A/Duck/England/1/1956 H11N6)
PA_I49A1Influenza A virus (strain A/Duck/Germany/1949 H10N7)
PA_I80A6Influenza A virus (strain A/Duck/Hokkaido/8/1980 H3N8)
PA_I00A0Influenza A virus (strain A/Duck/Hong Kong/2986.1/2000 H5N1 genotype C)
PA_I69A0Influenza A virus (strain A/England/878/1969 H3N2)
PA_I73A4Influenza A virus (strain A/Equine/London/1416/1973 H7N7)
PA_I86A3Influenza A virus (strain A/Equine/Tennessee/5/1986 H3N8)
PA_I47A0Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)
PA_I34A0Influenza A virus (strain A/Fowl plague virus/Rostock/8/1934 H7N1)
PA_I05A1Influenza A virus (strain A/Goose/Guangxi/345/2005 H5N1 genotype G)
PA_I79A7Influenza A virus (strain A/Grey teal/Australia/2/1979 H4N4)
PA_I02A1Influenza A virus (strain A/Guinea fowl/Hong Kong/38/2002 H5N1 genotype X0)
PA_I77AFInfluenza A virus (strain A/Gull/Maryland/704/1977 H13N6)
PA_I80ADInfluenza A virus (strain A/Gull/Minnesota/945/1980 H13N6)
PA_I36A0Influenza A virus (strain A/Henry/1936 H1N1)
PA_I40A0Influenza A virus (strain A/Hickox/1940 H1N1)
PA_I68A4Influenza A virus (strain A/Hong Kong/1/1968 H3N2)
PA_I97A1Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)
PA_I83A8Influenza A virus (strain A/Hong Kong/5/1983 H3N2)
PA_I80AAInfluenza A virus (strain A/India/6263/1980 H1N1)
PA_I57A0Influenza A virus (strain A/Japan/305/1957 H2N2)
PA_I93A0Influenza A virus (strain A/Kitakyushu/159/1993 H3N2)
PA_I68A5Influenza A virus (strain A/Korea/426/1968 H2N2)
PA_I57A2Influenza A virus (strain A/Leningrad/134/17/1957 H2N2)
PA_I57A1Influenza A virus (strain A/Leningrad/134/1957 H2N2)
PA_I57A3Influenza A virus (strain A/Leningrad/134/47/1957 H2N2)
PA_I54A2Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
PA_I78A3Influenza A virus (strain A/Mallard/New York/6750/1978 H2N2)
PA_I71A1Influenza A virus (strain A/Memphis/1/1971 H3N2)
PA_I72A4Influenza A virus (strain A/Memphis/101/1972 H3N2)
PA_I72A3Influenza A virus (strain A/Memphis/102/1972 H3N2)
PA_I76A6Influenza A virus (strain A/Memphis/110/1976 H3N2)
PA_I78A8Influenza A virus (strain A/Memphis/18/1978 H3N2)
PA_I78A7Influenza A virus (strain A/Memphis/2/1978 H3N2)
PA_I80A4Influenza A virus (strain A/Memphis/4/1980 H3N2)
PA_I00A1Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
PA_I68A6Influenza A virus (strain A/Northern Territory/60/1968 H3N2) (Influenza A virus ...
PA_I79A1Influenza A virus (strain A/Pintail/Alberta/119/1979 H4N6)
PA_I73A5Influenza A virus (strain A/Port Chalmers/1/1973 H3N2)
PA_I70A0Influenza A virus (strain A/Qu/7/1970 H3N2)
PA_I85A7Influenza A virus (strain A/Ruddy Turnstone/New Jersey/47/1985 H4N6)
PA_I06A0Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
PA_I01A0Influenza A virus (strain A/Silky Chicken/Hong Kong/SF189/2001 H5N1 genotype A)
PA_I02A4Influenza A virus (strain A/Silky Chicken/Hong Kong/YU100/2002 H5N1 genotype X3)
PA_I57A5Influenza A virus (strain A/Singapore/1/1957 H2N2)
PA_I77A4Influenza A virus (strain A/Swine/Colorado/1/1977 H3N2)
PA_I82A4Influenza A virus (strain A/Swine/Hong Kong/126/1982 H3N2)
PA_I78A9Influenza A virus (strain A/Swine/Hong Kong/81/1978 H3N2)
PA_I30A0Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)
PA_I77ADInfluenza A virus (strain A/Swine/Tennessee/26/1977 H1N1)
PA_I61A1Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
PA_I67A2Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)
PA_I67A0Influenza A virus (strain A/Tokyo/3/1967 H2N2)
PA_I83A4Influenza A virus (strain A/Turkey/Ireland/1378/1983 H5N8)
PA_I78ACInfluenza A virus (strain A/Turkey/Minnesota/501/1978 H6N8)
PA_I68A3Influenza A virus (strain A/Turkey/Ontario/6118/1968 H8N4)
PA_I66A1Influenza A virus (strain A/Turkey/Wisconsin/1/1966 H9N2)
PA_I72A2Influenza A virus (strain A/Udorn/307/1972 H3N2)
PA_I51A0Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
PA_I45A0Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
PA_I43A0Influenza A virus (strain A/USA:Iowa/1943 H1N1)
PA_I96A2Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
PA_I35A3Influenza A virus (strain A/USA:Phila/1935 H1N1)
PA_I07A0Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)
PA_I77ABInfluenza A virus (strain A/USSR/90/1977 H1N1)
PA_I75A3Influenza A virus (strain A/Victoria/3/1975 H3N2)
PA_I33A0Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain ...
PA_I000XInfluenza A virus (strain A/X-31 H3N2)

Polymerase basic protein 2 (RNA-directed RNA polymerase subunit P3)

Select_all Deselect_all  
PB2_I96A0Influenza A virus (strain A/Goose/Guangdong/1/1996 H5N1 genotype Gs/Gd) reference strain
PB2_I34A1Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
PB2_I80A2Influenza A virus (strain A/Seal/Massachusetts/1/1980 H7N7) reference strain
PB2_I80A8Influenza A virus (strain A/Turkey/Minnesota/833/1980 H4N2) reference strain
PB2_I60A0Influenza A virus (strain A/Ann Arbor/6/1960 H2N2)
PB2_I75A0Influenza A virus (strain A/Beijing/39/1975 H3N2)
PB2_I77AAInfluenza A virus (strain A/Brazil/11/1978 H1N1)

Polymerase basic protein 2

PB2_I18A0Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus ...
PB2_I77AGInfluenza A virus (strain A/Budgerigar/Hokkaido/1/1977 H4N6)
PB2_I02A0Influenza A virus (strain A/Chicken/Brescia/1902 H7N7)
PB2_I02A5Influenza A virus (strain A/Chicken/Hong Kong/96.1/2002 H5N1 genotype Y)
PB2_I02A6Influenza A virus (strain A/Chicken/Hong Kong/YU22/2002 H5N1 genotype Z)
PB2_I83A5Influenza A virus (strain A/Chicken/Pennsylvania/1/1983 H5N2)
PB2_I59A0Influenza A virus (strain A/Chicken/Scotland/1959 H5N1)
PB2_I03A1Influenza A virus (strain A/Chicken/Shantou/4231/2003 H5N1 genotype V)
PB2_I85A3Influenza A virus (strain A/Chicken/Victoria/1/1985 H7N7)
PB2_I000FInfluenza A virus (strain A/Chicken/Weybridge H7N7) (Influenza A virus (strain ...
PB2_I83A1Influenza A virus (strain A/Chile/1/1983 H1N1)
PB2_I96A3Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)

Polymerase basic protein 2

PB2_I56A1Influenza A virus (strain A/Duck/Czechoslovakia/1956 H4N6)
PB2_I56A2Influenza A virus (strain A/Duck/England/1/1956 H11N6)
PB2_I49A1Influenza A virus (strain A/Duck/Germany/1949 H10N7)
PB2_I80A6Influenza A virus (strain A/Duck/Hokkaido/8/1980 H3N8)
PB2_I00A0Influenza A virus (strain A/Duck/Hong Kong/2986.1/2000 H5N1 genotype C)
PB2_I69A0Influenza A virus (strain A/England/878/1969 H3N2)
PB2_I86A2Influenza A virus (strain A/Equine/Kentucky/2/1986 H3N8)
PB2_I73A4Influenza A virus (strain A/Equine/London/1416/1973 H7N7)
PB2_I56A3Influenza A virus (strain A/Equine/Prague/1/1956 H7N7)
PB2_I47A0Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)
PB2_I34A0Influenza A virus (strain A/Fowl plague virus/Rostock/8/1934 H7N1)
PB2_I05A1Influenza A virus (strain A/Goose/Guangxi/345/2005 H5N1 genotype G)
PB2_I79A7Influenza A virus (strain A/Grey teal/Australia/2/1979 H4N4)
PB2_I84A4Influenza A virus (strain A/Gull/Astrakhan/227/1984 H13N6)
PB2_I77AFInfluenza A virus (strain A/Gull/Maryland/704/1977 H13N6)
PB2_I80ADInfluenza A virus (strain A/Gull/Minnesota/945/1980 H13N6)
PB2_I36A0Influenza A virus (strain A/Henry/1936 H1N1)

Polymerase basic protein 2

PB2_I40A0Influenza A virus (strain A/Hickox/1940 H1N1)

Polymerase basic protein 2

PB2_I68A4Influenza A virus (strain A/Hong Kong/1/1968 H3N2)
PB2_I97A1Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)
PB2_I03A0Influenza A virus (strain A/Hong Kong/212/2003 H5N1 genotype Z+)
PB2_I83A8Influenza A virus (strain A/Hong Kong/5/1983 H3N2)
PB2_I80AAInfluenza A virus (strain A/India/6263/1980 H1N1)

Polymerase basic protein 2

PB2_I57A0Influenza A virus (strain A/Japan/305/1957 H2N2)
PB2_I79A4Influenza A virus (strain A/Kiev/59/1979 H1N1)
PB2_I93A0Influenza A virus (strain A/Kitakyushu/159/1993 H3N2)
PB2_I68A5Influenza A virus (strain A/Korea/426/1968 H2N2)
PB2_I57A2Influenza A virus (strain A/Leningrad/134/17/1957 H2N2)
PB2_I57A1Influenza A virus (strain A/Leningrad/134/1957 H2N2)
PB2_I57A3Influenza A virus (strain A/Leningrad/134/47/1957 H2N2)
PB2_I54A2Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)

Polymerase basic protein 2

PB2_I78A3Influenza A virus (strain A/Mallard/New York/6750/1978 H2N2)
PB2_I71A1Influenza A virus (strain A/Memphis/1/1971 H3N2)
PB2_I72A4Influenza A virus (strain A/Memphis/101/1972 H3N2)
PB2_I72A3Influenza A virus (strain A/Memphis/102/1972 H3N2)
PB2_I76A6Influenza A virus (strain A/Memphis/110/1976 H3N2)
PB2_I78A8Influenza A virus (strain A/Memphis/18/1978 H3N2)
PB2_I78A7Influenza A virus (strain A/Memphis/2/1978 H3N2)
PB2_I80A4Influenza A virus (strain A/Memphis/4/1980 H3N2)
PB2_I88A3Influenza A virus (strain A/Memphis/8/1988 H3N2)
PB2_I00A1Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)

Polymerase basic protein 2

PB2_I68A6Influenza A virus (strain A/Northern Territory/60/1968 H3N2) (Influenza A virus ...
PB2_I73A5Influenza A virus (strain A/Port Chalmers/1/1973 H3N2)
PB2_I70A0Influenza A virus (strain A/Qu/7/1970 H3N2)
PB2_I85A7Influenza A virus (strain A/Ruddy Turnstone/New Jersey/47/1985 H4N6)
PB2_I06A0Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)

Polymerase basic protein 2

PB2_I82A3Influenza A virus (strain A/Seal/Massachusetts/133/1982 H4N5)
PB2_I57A5Influenza A virus (strain A/Singapore/1/1957 H2N2)
PB2_I77A4Influenza A virus (strain A/Swine/Colorado/1/1977 H3N2)
PB2_I30A0Influenza A virus (strain A/Swine/Iowa/15/1930 H1N1)
PB2_I77ACInfluenza A virus (strain A/Swine/Tennessee/24/1977 H1N1)
PB2_I61A1Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)

Polymerase basic protein 2

PB2_I67A2Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)

Polymerase basic protein 2

PB2_I02A7Influenza A virus (strain A/Teal/China/2978.1/2002 H5N1 genotype W)
PB2_I67A0Influenza A virus (strain A/Tokyo/3/1967 H2N2)
PB2_I83A4Influenza A virus (strain A/Turkey/Ireland/1378/1983 H5N8)
PB2_I68A3Influenza A virus (strain A/Turkey/Ontario/6118/1968 H8N4)
PB2_I66A0Influenza A virus (strain A/Turkey/Ontario/7732/1966 H5N9)
PB2_I66A1Influenza A virus (strain A/Turkey/Wisconsin/1/1966 H9N2)
PB2_I72A2Influenza A virus (strain A/Udorn/307/1972 H3N2)
PB2_I51A0Influenza A virus (strain A/USA:Albany/12/1951 H1N1)

Polymerase basic protein 2

PB2_I45A0Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)

Polymerase basic protein 2

PB2_I43A0Influenza A virus (strain A/USA:Iowa/1943 H1N1)

Polymerase basic protein 2

PB2_I96A2Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)

Polymerase basic protein 2

PB2_I35A3Influenza A virus (strain A/USA:Phila/1935 H1N1)

Polymerase basic protein 2

PB2_I07A0Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)

Polymerase basic protein 2

PB2_I77ABInfluenza A virus (strain A/USSR/90/1977 H1N1)
PB2_I75A3Influenza A virus (strain A/Victoria/3/1975 H3N2)
PB2_I33A0Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain ...
PB2_I000XInfluenza A virus (strain A/X-31 H3N2)

Genome polyprotein

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POLG_POL1SPoliovirus type 1 (strain Sabin)
POLG_POL2LPoliovirus type 2 (strain Lansing)
POLG_POL2WPoliovirus type 2 (strain W-2)
POLG_POL32Poliovirus type 3 (strain 23127)
POLG_POL3LPoliovirus type 3 (strains P3/Leon/37 and P3/Leon 12A[1]B)

Non-structural polyprotein (Polyprotein nsP1234) (P1234)

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POLN_CHIKSChikungunya virus (strain S27-African prototype) (CHIKV) reference strain
POLN_SFVSemliki forest virus (SFV) reference strain
POLN_SINDVSindbis virus (SINV) reference strain
POLN_AURAVAura virus (AURAV)
POLN_BFVBarmah forest virus (BFV)
POLN_CHIK3Chikungunya virus (strain 37997) (CHIKV)
POLN_EEEVFEastern equine encephalitis virus (strain Florida 91-469) (EEEV) (Eastern ...
POLN_EEEV1Eastern equine encephalitis virus (strain PE-0.0155) (EEEV) (Eastern equine ...
POLN_EEEV8Eastern equine encephalitis virus (strain PE-3.0815) (EEEV) (Eastern equine ...
POLN_GETVGetah virus (GETV)
POLN_MAYABMayaro virus (strain Brazil) (MAYV)
POLN_ONNVGO'nyong-nyong virus (strain Gulu) (ONNV)
POLN_ONNVIO'nyong-nyong virus (strain Igbo Ora) (ONNV) (Igbo Ora virus)
POLN_ONNVSO'nyong-nyong virus (strain SG650) (ONNV)
POLN_RRVNRoss river virus (strain NB5092) (RRV)
POLN_SAGVSagiyama virus (SAGV)
POLN_SPDVSalmon pancreas disease virus (SPDV)
POLN_SINDOSindbis virus subtype Ockelbo (strain Edsbyn 82-5) (OCKV) (Ockelbo virus)
POLN_SLDVSleeping disease virus (SDV)
POLN_EEVV3Venezuelan equine encephalitis virus (strain 3880) (VEEV)
POLN_EEVVCVenezuelan equine encephalitis virus (strain CPA201) (VEEV)
POLN_EEVVMVenezuelan equine encephalitis virus (strain Mena II) (VEEV)
POLN_EEVVPVenezuelan equine encephalitis virus (strain P676) (VEEV)
POLN_EEVVTVenezuelan equine encephalitis virus (strain Trinidad donkey) (VEEV)
POLN_WEEVWestern equine encephalitis virus (WEEV)

RNA-directed RNA polymerase catalytic subunit (EC 2.7.7.48) (Polymerase basic protein 1) (PB1) (RNA-directed RNA polymerase subunit P1)

Select_all Deselect_all  
RDRP_I96A0Influenza A virus (strain A/Goose/Guangdong/1/1996 H5N1 genotype Gs/Gd) reference strain
RDRP_I34A1Influenza A virus (strain A/Puerto Rico/8/1934 H1N1) reference strain
RDRP_I80A2Influenza A virus (strain A/Seal/Massachusetts/1/1980 H7N7) reference strain
RDRP_I80A8Influenza A virus (strain A/Turkey/Minnesota/833/1980 H4N2) reference strain
RDRP_I60A0Influenza A virus (strain A/Ann Arbor/6/1960 H2N2)
RDRP_I56A0Influenza A virus (strain A/Beijing/11/1956 H1N1)
RDRP_I75A0Influenza A virus (strain A/Beijing/39/1975 H3N2)
RDRP_I77AAInfluenza A virus (strain A/Brazil/11/1978 H1N1)
RDRP_I18A0Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza A virus ...
RDRP_I97A0Influenza A virus (strain A/Chicken/Hong Kong/220/1997 H5N1 genotype Gs/Gd)
RDRP_I02A2Influenza A virus (strain A/Chicken/Hong Kong/31.2/2002 H5N1 genotype X1)
RDRP_I02A3Influenza A virus (strain A/Chicken/Hong Kong/37.4/2002 H5N1 genotype X2)
RDRP_I01A3Influenza A virus (strain A/Chicken/Hong Kong/715.5/2001 H5N1 genotype E)
RDRP_I02A6Influenza A virus (strain A/Chicken/Hong Kong/YU22/2002 H5N1 genotype Z)
RDRP_I83A5Influenza A virus (strain A/Chicken/Pennsylvania/1/1983 H5N2)
RDRP_I83A6Influenza A virus (strain A/Chicken/Pennsylvania/1370/1983 H5N2)
RDRP_I59A0Influenza A virus (strain A/Chicken/Scotland/1959 H5N1)
RDRP_I03A1Influenza A virus (strain A/Chicken/Shantou/4231/2003 H5N1 genotype V)
RDRP_I85A3Influenza A virus (strain A/Chicken/Victoria/1/1985 H7N7)
RDRP_I83A1Influenza A virus (strain A/Chile/1/1983 H1N1)
RDRP_I96A3Influenza A virus (strain A/China:Nanchang/11/1996 H1N1)
RDRP_I56A1Influenza A virus (strain A/Duck/Czechoslovakia/1956 H4N6)
RDRP_I56A2Influenza A virus (strain A/Duck/England/1/1956 H11N6)
RDRP_I49A1Influenza A virus (strain A/Duck/Germany/1949 H10N7)
RDRP_I80A6Influenza A virus (strain A/Duck/Hokkaido/8/1980 H3N8)
RDRP_I00A0Influenza A virus (strain A/Duck/Hong Kong/2986.1/2000 H5N1 genotype C)
RDRP_I73A6Influenza A virus (strain A/Dunedin/4/1973 H3N2)
RDRP_I69A0Influenza A virus (strain A/England/878/1969 H3N2)
RDRP_I73A4Influenza A virus (strain A/Equine/London/1416/1973 H7N7)
RDRP_I86A3Influenza A virus (strain A/Equine/Tennessee/5/1986 H3N8)
RDRP_I47A0Influenza A virus (strain A/Fort Monmouth/1/1947 H1N1)
RDRP_I05A1Influenza A virus (strain A/Goose/Guangxi/345/2005 H5N1 genotype G)
RDRP_I79A7Influenza A virus (strain A/Grey teal/Australia/2/1979 H4N4)
RDRP_I77AFInfluenza A virus (strain A/Gull/Maryland/704/1977 H13N6)
RDRP_I80ADInfluenza A virus (strain A/Gull/Minnesota/945/1980 H13N6)
RDRP_I36A0Influenza A virus (strain A/Henry/1936 H1N1)
RDRP_I40A0Influenza A virus (strain A/Hickox/1940 H1N1)
RDRP_I68A4Influenza A virus (strain A/Hong Kong/1/1968 H3N2)
RDRP_I97A1Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)
RDRP_I03A0Influenza A virus (strain A/Hong Kong/212/2003 H5N1 genotype Z+)
RDRP_I83A8Influenza A virus (strain A/Hong Kong/5/1983 H3N2)
RDRP_I80AAInfluenza A virus (strain A/India/6263/1980 H1N1)
RDRP_I57A0Influenza A virus (strain A/Japan/305/1957 H2N2)
RDRP_I79A4Influenza A virus (strain A/Kiev/59/1979 H1N1)
RDRP_I93A0Influenza A virus (strain A/Kitakyushu/159/1993 H3N2)
RDRP_I68A5Influenza A virus (strain A/Korea/426/1968 H2N2)
RDRP_I57A2Influenza A virus (strain A/Leningrad/134/17/1957 H2N2)
RDRP_I57A1Influenza A virus (strain A/Leningrad/134/1957 H2N2)
RDRP_I57A3Influenza A virus (strain A/Leningrad/134/47/1957 H2N2)
RDRP_I54A2Influenza A virus (strain A/Malaysia:Malaya/302/1954 H1N1)
RDRP_I78A3Influenza A virus (strain A/Mallard/New York/6750/1978 H2N2)
RDRP_I71A1Influenza A virus (strain A/Memphis/1/1971 H3N2)
RDRP_I72A4Influenza A virus (strain A/Memphis/101/1972 H3N2)
RDRP_I72A3Influenza A virus (strain A/Memphis/102/1972 H3N2)
RDRP_I76A6Influenza A virus (strain A/Memphis/110/1976 H3N2)
RDRP_I78A8Influenza A virus (strain A/Memphis/18/1978 H3N2)
RDRP_I78A7Influenza A virus (strain A/Memphis/2/1978 H3N2)
RDRP_I80A4Influenza A virus (strain A/Memphis/4/1980 H3N2)
RDRP_I88A3Influenza A virus (strain A/Memphis/8/1988 H3N2)
RDRP_I00A1Influenza A virus (strain A/New Zealand:South Canterbury/35/2000 H1N1)
RDRP_I68A6Influenza A virus (strain A/Northern Territory/60/1968 H3N2) (Influenza A virus ...
RDRP_I73A5Influenza A virus (strain A/Port Chalmers/1/1973 H3N2)
RDRP_I70A0Influenza A virus (strain A/Qu/7/1970 H3N2)
RDRP_I06A0Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1)
RDRP_I01A0Influenza A virus (strain A/Silky Chicken/Hong Kong/SF189/2001 H5N1 genotype A)
RDRP_I02A4Influenza A virus (strain A/Silky Chicken/Hong Kong/YU100/2002 H5N1 genotype X3)
RDRP_I57A5Influenza A virus (strain A/Singapore/1/1957 H2N2)
RDRP_I77A4Influenza A virus (strain A/Swine/Colorado/1/1977 H3N2)
RDRP_I82A4Influenza A virus (strain A/Swine/Hong Kong/126/1982 H3N2)
RDRP_I81A4Influenza A virus (strain A/Swine/Ontario/2/1981 H1N1)
RDRP_I77ADInfluenza A virus (strain A/Swine/Tennessee/26/1977 H1N1)
RDRP_I61A1Influenza A virus (strain A/Swine/Wisconsin/1/1961 H1N1)
RDRP_I67A2Influenza A virus (strain A/Swine/Wisconsin/1/1967 H1N1)
RDRP_I02A7Influenza A virus (strain A/Teal/China/2978.1/2002 H5N1 genotype W)
RDRP_I67A0Influenza A virus (strain A/Tokyo/3/1967 H2N2)
RDRP_I83A4Influenza A virus (strain A/Turkey/Ireland/1378/1983 H5N8)
RDRP_I78ACInfluenza A virus (strain A/Turkey/Minnesota/501/1978 H6N8)
RDRP_I68A3Influenza A virus (strain A/Turkey/Ontario/6118/1968 H8N4)
RDRP_I66A0Influenza A virus (strain A/Turkey/Ontario/7732/1966 H5N9)
RDRP_I66A1Influenza A virus (strain A/Turkey/Wisconsin/1/1966 H9N2)
RDRP_I72A2Influenza A virus (strain A/Udorn/307/1972 H3N2)
RDRP_I51A0Influenza A virus (strain A/USA:Albany/12/1951 H1N1)
RDRP_I45A0Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)
RDRP_I43A0Influenza A virus (strain A/USA:Iowa/1943 H1N1)
RDRP_I96A2Influenza A virus (strain A/USA:Memphis/10/1996 H1N1)
RDRP_I35A3Influenza A virus (strain A/USA:Phila/1935 H1N1)
RDRP_I07A0Influenza A virus (strain A/USA:Texas/UR06-0195/2007 H1N1)
RDRP_I77ABInfluenza A virus (strain A/USSR/90/1977 H1N1)
RDRP_I75A3Influenza A virus (strain A/Victoria/3/1975 H3N2)
RDRP_I33A0Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain ...
RDRP_I88A7Influenza A virus (strain A/Wisconsin/3523/1988 H1N1)
RDRP_I000XInfluenza A virus (strain A/X-31 H3N2)