VIRALZONE NEWS

Circular ssRNA virus/viroid March 2017

Viroids are plant selfish circular complementary RNA entities that behave like viruses but are not classified as such because they do not encode for proteins. Viroids can replicate either by symmetrical or assymmetrical rolling circle. Surprisingly the human hepatitis Delta virus genome and it’s replication are similar to those of plant avsunviroidae, suggesting a common ancestor. Hepatitis D is the only known virus of its kind, and was discovered because it does have an impact on human health. We can expect to discover more of those virus/viroid in the future

Communication between viruses guides lysis-lysogeny decisions March 2017

In phi3T bacteriophage, the decision between latency and replication depends on the concentration of a small peptide that is secreted by infecting viruses and an intracellular receptor that acts as a transcriptional regulator. When a virus infects an as-yet-uninfected bacteria in which the peptide has accumulated, latency will be promoted.

HIV and Tuberculosis syndemic December 2016

About one third of deaths among HIV-seropositive patients worldwide are due to co-infection with Mycobacterium tuberculosis (MTB). By infecting the same host, both pathogens replicate much better than alone. This syndemic is induced by a convergent dis-regulation of host immune response by HIV and MTB



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Virology and Bioinformatics from Virology.ca
Virus and bioinformatics articles with some microbiology and immunology thrown in for good measure Curated by Dr. Chris Upton


Publication: ViralZone: a knowledge resource to understand virus diversity. Hulo C, de Castro E, Masson P, Bougueleret L, Bairoch A, Xenarios I, Le Mercier P. Nucleic Acids Res. 2011 Jan;39(Database issue):D576-82.

ViralZone current statistics
March, 2017
653 Virus description pages:
  • 101 Families
  • 543 Genera
  • 9 individual Species

216 Viral molecular biology pages

Linking to:
(UniProt release 2017_02)


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