Flaviviridae (taxid:11050)

More on Zika virus here

VIRION

Enveloped, spherical, about 50 nm in diameter. The surface proteins are arranged in an icosahedral-like symmetry.
Source: Zhang et al

GENOME

Monopartite, linear, ssRNA(+) genome of about 9.7-12 kb. The genome 3' terminus is not polyadenylated but forms a loop structure. The 5' end has a methylated nucleotide cap (to allow translation) or a genome-linked protein (VPg).

GENE EXPRESSION

The virion RNA is infectious and serves as both the genome and the viral messenger RNA. The whole genome is translated into a polyprotein, which is processed co- and post-translationally by host and viral proteases.

ENZYMES

RNA-dependent RNA polymerase [NS5]
Cell-type capping
- RNA TPAse [NS3]
- GTase, N7Mtase, 2'O methylase [NS5]
Polyprotein major protease (Peptidase S7, S29 or S31) [NS3]

REPLICATION

CYTOPLASMIC

Attachement of the viral envelope protein E to host receptors mediates internalization into the host cell by clathrin-mediated endocytosis or by apoptotic mimicry
Fusion of virus membrane with host endosomal membrane. RNA genome is released into the cytoplasm.
The positive-sense genomic ssRNA is translated into a polyprotein, which is cleaved into all structural and non structural proteins (to yield the replication proteins).
Replication takes place at the surface of endoplasmic reticulum in cytoplasmic viral factories. A dsRNA genome is synthesized from the genomic ssRNA(+).
The dsRNA genome is transcribed/replicated thereby providing viral mRNAs/new ssRNA(+) genomes.
Virus assembly occurs at the endoplasmic reticulum and seems to be facilitated by the viral ionic channel. The virion buds at the endoplasmic reticulum and is transported to the Golgi apparatus.
Release of new virions by exocytosis.

DB LINKS

TAXONOMY Group IV; ssRNA positive-strand viruses

Realm:	Riboviria
Kingdom:	Orthornavirae
Phylum:	Kitrinoviricota
Class:	Flasuviricetes
Order:	Amarillovirales
Family:	Flaviridae
Genus:	Orthoflavivirus Hepacivirus Pegivirus Pestivirus

VIRUS

Hepacivirus C
Pegivirus A
Pestivirus A
Yellow fever virus
Apoi virus
Aroa virus
Bagaza virus
Banzi virus
Bouboui virus
Bukalasa bat virus
Cacipacore virus
Carey Island virus
Cowbone Ridge virus
Dakar bat virus
Dengue virus
Edge Hill virus
Entebbe bat virus
Gadgets Gully virus
Hepacivirus A
Hepacivirus B
Hepacivirus D
Hepacivirus E
Hepacivirus F
Hepacivirus G
Hepacivirus H
Hepacivirus I
Hepacivirus J
Hepacivirus K
Hepacivirus L
Hepacivirus M
Hepacivirus N
Ilheus virus
Israel turkey meningoencephalomyelitis virus
Japanese encephalitis virus
Jugra virus
Jutiapa virus
Kadam virus
Kedougou virus
Kokobera virus
Koutango virus
Kyasanur Forest disease virus
Langat virus
Louping ill virus
Meaban virus
Modoc virus
Montana myotis leukoencephalitis virus
Murray Valley encephalitis virus
Ntaya virus
Omsk hemorrhagic fever virus
Pegivirus B
Pegivirus C
Pegivirus D
Pegivirus E
Pegivirus F
Pegivirus G
Pegivirus H
Pegivirus I
Pegivirus J
Pegivirus K
Pestivirus B
Pestivirus C
Pestivirus D
Pestivirus E
Pestivirus F
Pestivirus G
Pestivirus H
Pestivirus I
Pestivirus J
Pestivirus K
Phnom Penh bat virus
Powassan virus
Rio Bravo virus
Royal Farm virus
Saboya virus
Saint Louis encephalitis virus
Sal Vieja virus
San Perlita virus
Saumarez Reef virus
Sepik virus
Tembusu virus
Tick-borne encephalitis virus
Tyuleniy virus
Uganda S virus
Usutu virus
Wesselsbron virus
West Nile virus
Yaounde virus
Yokose virus
Zika virus

Host

NATURAL HOSTS Human, mammals.
Vector:Ticks or mosquitoes

TROPISM

INTERACTIONS Cell receptors:
DENV: heparan sulfate.
HCV: Heparan sulfate, LDL-R, CD81, CLDN1.
Host-virus interaction

Ecology and disease

GEOGRAPHY Worldwide.

ASSOCIATED DISEASES Hepaciviruses: hepatitis.
Pestiviruses: hemorrhagic syndromes, abortion, fatal mucosal disease.
Flavivirus: hemorrhagic fever, encephalitis

TRANSMISSION

VACCINE Japanese encephalitis virus, Tick-borne encephalitis virus, West Nile virus, Yellow fever virus, Bovine diarrhea virus, Classical swine fever virus.

ANTIVIRAL DRUGS Ribavirin (Guanosine analog)
[YFV, WNV]"Favipiravir":http://en.wikipedia.org/wiki/Favipiravir (Experimental, nucleotide analog)
[DENV]"Celgosivir":https://en.wikipedia.org/wiki/Celgosivir (Experimental, glycosyl transferase inhibitor)

Host-virus interaction

Adaptive immune response inhibition

Dengue NS1 protein inhibits host complement by binding C4 and reducing C4b deposition and C3 convertase activity. Through this mechanism, NS1 protects DENV from complement-dependent neutralization in solution. .

Apoptosis modulation

Flaviviruses NS3 induces apoptosis through host caspases activation .

Autophagy modulation

Flaviviruses NS4A and NS4B induces autophagy signaling .

Cell-cycle modulation

Hepatitis C virus induces down-regulation of the retinoblastoma tumor suppressor and G1/S host cell cycle checkpoint dysregulation .

Innate immune response inhibition

Hepatitis C virus inhibits the interferon signaling pathway by blocking the IFN receptors , STAT1 and TYK2 , whilst Dengue virus blocks STAT2
Hepatitis C virus inhibits the host IFN-mediated response by blocking host MAVS , TRAFs and TBK1-IKBKE-DDX3 complex , whilst pestiviruses N(pro) blocks host IRF-3 .

Host gene expression shutoff by virus

Hepatitis C virus activates PKR about 12h p.i. to shutoff host translation through the PKR-mediated phosphorylation of the eIF2alpha initiation factor .

Matching UniProtKB/Swiss-Prot entries

(all links/actions below point to uniprot.org website)

108 entries grouped by strain

reorder by protein

2 entries

Hepatitis C virus genotype 1a (isolate H77) (HCV) reference strain

F_HCV77 F protein (Alternate reading frame protein/F-protein) (ARFP/F) (Frameshifted protein) (p16) (p17)

POLG_HCV77 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1A1R; 1A1V; 1CWX; 1HEI; 1JR6; 1N1L; 1ONB; 1R7C; 1R7D; 1R7E; 1R7F; 1R7G; 1RGQ; 2A4R; 2F9V; 2HD0; 2JXF; 2KDR; 2N1P; 2O8M; 2OBO; 2OBQ; 2OC0; 2OC1; 2OC7; 2OC8; 2OIN; 2P59; 2QV1; 2XI2; 2XI3; 2XNI; 3RC4; 3RC5; 4CL1; 4JZN; 4JZO; 4MWF; 4N0Y; 4Q0X; 4XVJ; 4Z0X; 5EOC; 5ERW; 5FGB; 5FGC; 5JZI; 5YXN; 5YXU; 6BQJ; 6BQK; 6BZU; 6BZV; 6BZW; 6BZY; 6UYD; 6WO5; 6WOQ; 7DUU

2 entries

Zika virus (ZIKV) reference strain

POLG_ZIKV Genome polyprotein [Cleaved into: Capsid protein C (Capsid protein) (Core protein); Protein prM ...

5GJ4; 5GPI; 5GXJ; 5JPS; 5JRZ; 5K6K; 5RHG; 5RHH; 5RHI; 5RHJ; 5RHK; 5RHL; 5RHM; 5RHO; 5RHP; 5RHQ; 5RHR; 5RHS; 5RHT; 5RHU; 5RHV; 5RHW; 5RHX; 5RHY; 5T1V; 5TFN; 5TFO; 5TFR; 5TMH; 5U04; 5U0B; 5U0C; 5VI7; 5VIM; 5W41; 5Y4Z; 5YOD; 5YOF; 5Z0R; 5Z0V; 5ZMQ; 5ZMS; 5ZOB; 6ADW; 6ADX; 6ADY; 6JPW; 6KK2; 6KK3; 6KK4; 6KK5; 6KK6; 6KPQ; 6L50; 6MH3; 6UX2; 6WCZ; 6Y3B; 7G9K; 7G9L; 7G9M; 7G9N; 7G9O; 7G9P; 7G9Q; 7G9R; 7G9S; 7G9T; 7G9U; 7G9V; 7G9W; 7G9X; 7G9Y; 7G9Z; 7GA0; 7GA1; 7GA2; 7GA3; 7GA4; 7GA5; 7GA6; 7GA7; 7H1H; 7H1I; 7H1J; 7H1K; 7H1L; 7H1M; 7H1N; 7H1O; 7H1P; 7H1Q; 7H1R; 7H1S; 7H1T; 7H1U; 7H1V; 7H1W; 7H1X; 7H1Y; 7H1Z; 7H20; 7H21; 7H22; 7H23; 7H24; 7H25; 7H26; 7H27; 7H28; 7H29; 7H2A; 7H2B; 7H2C; 7H2D; 7H2E; 7H2F; 7H2G; 7H2H; 7H2I; 7H2J; 7H2K; 7H2L; 7H2M; 7H2N; 7H2O; 7H2P; 7H2Q; 7H2R; 7H2S; 7HOJ; 7HOK; 7HOL; 7HOM; 7HOP; 7HOQ; 7HOR; 7HOS; 7HOT; 7HOU; 7HOV; 7HOW; 7HOX; 7HOZ; 7HP0; 7HP1; 7HP2; 7HP4; 7HP5; 7HP6; 7HP7; 7HP8; 7HP9; 7HPA; 7HPB; 7HPC; 7HPD; 7HPE; 7HPF; 7HPG; 7HPH; 7I1K; 7I1L; 7I1M; 7I1N; 7I1O; 7I1P; 7I1Q; 7I1S; 7I1T; 7I1V; 7I1W; 7I1Y; 7I1Z; 7I20; 7I21; 7I22; 7O2M; 7O55; 7OBV; 7OC2; 7PFQ; 7PFY; 7PFZ; 7PG1; 7PGC; 7VLG; 7VLH; 7VLI; 7VXX; 7VXY; 7ZLC; 7ZLD; 7ZMI; 7ZNO; 7ZPD; 7ZQ1; 7ZQF; 7ZTM; 7ZUM; 7ZV4; 7ZVV; 7ZW5; 7ZWK; 7ZYS; 8A15; 8AQA; 8AQB; 8AQK; 8PEM; 8PN6; 8UM3; 8V7R; 8V7U; 8WN8; 8WNP; 8WNU; 8WO0; 8WO4

UORF_ZIKV uORF protein

1 entry

Bovine viral diarrhea virus (isolate NADL) (BVDV) (Mucosal disease virus) reference strain

1 entry

Dengue virus type 1 (strain Nauru/West Pac/1974) (DENV-1) reference strain

1 entry

Yellow fever virus (strain 17D vaccine) (YFV) reference strain

3 entries

Zika virus (isolate ZIKV/Human/Cambodia/FSS13025/2010) (ZIKV)

POLG_ZIKVK Genome polyprotein [Cleaved into: Capsid protein C (Capsid protein) (Core protein); Protein prM ...

6UTA; 7BPK; 7BQ5

ORF1_ZIKVK uORF1 protein

ORF2_ZIKVK uORF2 protein

3 entries

Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013) (ZIKV)

POLG_ZIKVF Genome polyprotein [Cleaved into: Capsid protein C (Capsid protein) (Core protein); Protein prM ...

5GOZ; 5GP1; 5H30; 5H32; 5H37; 5IRE; 5IZ7; 5JMT; 5KQR; 5KQS; 5KVE; 5LBS; 5LBV; 5LCV; 5M5B; 5MRK; 5NJU; 5NJV; 5U4W; 5UHY; 5ULP; 5Y0A; 5Y6M; 5Y6N; 6CO8; 6I7P; 6JFH; 6JFI; 6LD1; 6LD2; 6LD3; 6LD4; 6LD5; 6NIP; 6NIU; 6PLK; 6RWZ; 6S0J; 6UM3; 7A3N; 7A3U; 7BSD; 7BU8; 7BUA; 7M1V; 7T17; 7V2Z; 7YAR; 7YW7; 7YW8; 8EE5; 8EE8; 8EED; 8EEE

ORF1_ZIKVF uORF1 protein

ORF2_ZIKVF uORF2 protein

2 entries

Hepatitis C virus genotype 1a (isolate 1) (HCV)

POLG_HCV1 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1RTL; 2A4G; 2GVF; 3EYD; 3HKW; 3KN2; 3QGH; 3QGI; 3RC4; 3RC5; 3SU4; 6MVO; 6N4N; 6VDO; 7MM3; 7MM4; 7MM9; 7MMA; 7MMB; 7MMC; 7MMD; 7MME; 7MMK; 7MML

F_HCV1 F protein (Alternate reading frame protein/F-protein) (ARFP/F) (Frameshifted protein) (p16) (p17)

2 entries

Japanese encephalitis virus (strain Jaoars982) (JEV)

POLS_JAEVJ Structural polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; ...

POLG_JAEVJ Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

5YWO; 5YWP

2 entries

Japanese encephalitis virus (strain M28) (JEV)

2 entries

Japanese encephalitis virus (strain SA(v)) (JEV)

2 entries

Japanese encephalitis virus (strain SA-14) (JEV)

POLS_JAEV1 Structural polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; ...

POLG_JAEV1 Genome polyprotein [Cleaved into: Capsid protein C (Core protein); Protein prM; Peptide pr; Small ...

2Z83; 3P54; 4HDG; 4HDH; 4K6M; 4MTP; 5MV1; 5MV2; 5O19; 5O36; 5OW2; 5WSN; 5YWO; 5YWP

1 entry

Alkhumra hemorrhagic fever virus (ALKV) (Alkhurma hemorrhagic fever virus)

1 entry

Banzi virus (BANV)

1 entry

Bovine viral diarrhea virus (strain CP7) (BVDV) (Mucosal disease virus)

1 entry

Bovine viral diarrhea virus (strain SD-1) (BVDV) (Mucosal disease virus)

1 entry

Bussuquara virus (BUSV)

1 entry

Classical swine fever virus (strain Alfort/Tuebingen) (CSFV) (Hog cholera virus)

1 entry

Classical swine fever virus (strain Brescia) (CSFV) (Hog cholera virus)

1 entry

Dengue virus type 1 (strain Brazil/97-11/1997) (DENV-1)

1 entry

Dengue virus type 1 (strain Singapore/S275/1990) (DENV-1)

1 entry

Dengue virus type 2 (isolate Thailand/0168/1979) (DENV-2)

1 entry

Dengue virus type 2 (strain 16681-PDK53) (DENV-2)

1 entry

Dengue virus type 2 (strain Jamaica/1409/1983) (DENV-2)

1 entry

Dengue virus type 2 (strain Peru/IQT2913/1996) (DENV-2)

1 entry

Dengue virus type 2 (strain Puerto Rico/PR159-S1/1969) (DENV-2)

1 entry

Dengue virus type 2 (strain Thailand/16681/1984) (DENV-2)

1 entry

Dengue virus type 2 (strain Thailand/NGS-C/1944) (DENV-2)

1 entry

Dengue virus type 3 (strain China/80-2/1980) (DENV-3)

1 entry

Dengue virus type 3 (strain Martinique/1243/1999) (DENV-3)

1 entry

Dengue virus type 3 (strain Philippines/H87/1956) (DENV-3)

1 entry

Dengue virus type 3 (strain Singapore/8120/1995) (DENV-3)

1 entry

Dengue virus type 3 (strain Sri Lanka/1266/2000) (DENV-3)

1 entry

Dengue virus type 4 (strain Dominica/814669/1981) (DENV-4)

1 entry

Dengue virus type 4 (strain Philippines/H241/1956) (DENV-4)

1 entry

Dengue virus type 4 (strain Singapore/8976/1995) (DENV-4)

1 entry

Dengue virus type 4 (strain Thailand/0348/1991) (DENV-4)

1 entry

Dengue virus type 4 (strain Thailand/0476/1997) (DENV-4)

1 entry

Edge Hill virus (EHV)

1 entry

Hepatitis C virus genotype 1b (isolate BK) (HCV)

POLG_HCVBK Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1A1Q; 1BT7; 1C2P; 1CSJ; 1CU1; 1GX5; 1GX6; 1JXP; 1NHU; 1NHV; 1NS3; 1OS5; 1QUV; 2AWZ; 2AX0; 2AX1; 2BRK; 2BRL; 2DXS; 2GIQ; 2GIR; 2HAI; 2HWH; 2HWI; 2I1R; 2JC0; 2JC1; 2O5D; 2WCX; 2WHO; 2WRM; 2XWY; 2ZKU; 3BR9; 3BSA; 3BSC; 3CDE; 3CIZ; 3CJ0; 3CJ2; 3CJ3; 3CJ4; 3CJ5; 3CO9; 3CVK; 3CWJ; 3D28; 3D5M; 3E51; 3FQK; 3FRZ; 3G86; 3GYN; 3H2L; 3H59; 3H5S; 3H5U; 3H98; 3IGV; 3MF5; 3RVB; 3UA7; 3UDL; 3VQS; 4A92; 4B6E; 4B6F; 4B71; 4B73; 4B74; 4B75; 4B76; 4DGV; 4DGY; 4EO6; 4EO8; 4IH5; 4IH6; 4IH7; 4K8B; 4KAI; 4KB7; 4KBI; 4KE5; 4MIA; 4MIB; 4MK7; 4MK8; 4MK9; 4MKA; 4MKB; 4TN2; 4WXP; 5FPS; 5FPT; 5FPY; 5KZP; 5W2E; 6MVP; 6W4G; 8OHM

1 entry

Hepatitis C virus genotype 1b (isolate Con1) (HCV)

1 entry

Hepatitis C virus genotype 1b (isolate HC-J1) (HCV)

1 entry

Hepatitis C virus genotype 1b (isolate HC-JT) (HCV)

1 entry

Hepatitis C virus genotype 1b (isolate HCR6) (HCV)

1 entry

Hepatitis C virus genotype 1b (isolate Japanese) (HCV)

1 entry

Hepatitis C virus genotype 1b (isolate Taiwan) (HCV)

1 entry

Hepatitis C virus genotype 1b (strain HC-J4) (HCV)

POLG_HCVJ4 Genome polyprotein [Cleaved into: Core protein precursor (Capsid protein C) (p23); Mature core ...

1NB4; 1NB6; 1NB7; 2F55; 2MTS; 2XHU; 2XHV; 2XHW; 2YOJ; 3CSO; 3GNV; 3GNW; 3GOL; 3HKY; 3LKH; 3MWV; 3MWW; 3SKA; 3SKE; 3SKH; 3TYQ; 3TYV; 3U4O; 3U4R; 3UPH; 3UPI; 4DRU; 4EAW; 4GMC; 4IZ0; 4J02; 4J04; 4J06; 4J08; 4J0A; 4JJS; 4JJU; 4JTW; 4JTY; 4JTZ; 4JU1; 4JU2; 4JU3; 4JU4; 4JU6; 4JU7; 4JVQ; 4JY0; 4JY1; 4MZ4; 4OOW; 4RY4; 4RY5; 4RY6; 4RY7; 5CZB; 5NPH; 5NPI

1 entry

Hepatitis C virus genotype 1c (isolate HC-G9) (HCV)

1 entry

Hepatitis C virus genotype 1c (isolate India) (HCV)

1 entry

Hepatitis C virus genotype 2a (isolate HC-J6) (HCV)

1 entry

Hepatitis C virus genotype 2a (isolate JFH-1) (HCV)

1 entry

Hepatitis C virus genotype 2b (isolate HC-J8) (HCV)

1 entry

Hepatitis C virus genotype 2b (isolate JPUT971017) (HCV)

1 entry

Hepatitis C virus genotype 2c (isolate BEBE1) (HCV)

1 entry

Hepatitis C virus genotype 2k (isolate VAT96) (HCV)

1 entry

Hepatitis C virus genotype 3a (isolate NZL1) (HCV)

1 entry

Hepatitis C virus genotype 3a (isolate k3a) (HCV)

1 entry

Hepatitis C virus genotype 3b (isolate Tr-Kj) (HCV)

1 entry

Hepatitis C virus genotype 3k (isolate JK049) (HCV)

1 entry

Hepatitis C virus genotype 4a (isolate ED43) (HCV)

1 entry

Hepatitis C virus genotype 5a (isolate EUH1480) (HCV)

1 entry

Hepatitis C virus genotype 5a (isolate SA13) (HCV)

1 entry

Hepatitis C virus genotype 6a (isolate 6a33) (HCV)

1 entry

Hepatitis C virus genotype 6a (isolate EUHK2) (HCV)

1 entry

Hepatitis C virus genotype 6b (isolate Th580) (HCV)

1 entry

Hepatitis C virus genotype 6d (isolate VN235) (HCV)

1 entry

Hepatitis C virus genotype 6g (isolate JK046) (HCV)

1 entry

Hepatitis C virus genotype 6h (isolate VN004) (HCV)

1 entry

Hepatitis C virus genotype 6k (isolate VN405) (HCV)

1 entry

Hepatitis GB virus B (GBV-B) (GB virus B)

1 entry

Ilheus virus (ILHV)

1 entry

Kokobera virus (KOKV)

1 entry

Kunjin virus (strain MRM61C)

1 entry

Kyasanur forest disease virus (KFDV)

1 entry

Langat virus (strain TP21)

1 entry

Louping ill virus (Li)

1 entry

Mosquito cell fusing agent (CFA flavivirus)

1 entry

Murray valley encephalitis virus (strain MVE-1-51) (MVEV)

1 entry

Omsk hemorrhagic fever virus (OHFV)

1 entry

Rocio virus (ROCV)

1 entry

Tembusu virus (TMUV)

1 entry

Tick-borne encephalitis virus (strain Hypr) (TBEV)

1 entry

Tick-borne encephalitis virus European subtype (strain Neudoerfl) (NEUV) (Neudoerfl virus)

1 entry

Tick-borne encephalitis virus Far Eastern subtype (strain Sofjin) (SOFV) (Sofjin virus)

1 entry

Tick-borne powassan virus (strain LB) (POWV) (Powassan virus)

1 entry

Usutu virus (USUV)

1 entry

Wesselsbron virus (WSLV)

1 entry

West Nile virus (WNV)

1 entry

West Nile virus (strain NY-99) (WNV) (West Nile virus (strain NY-1999))

1 entry

Yellow fever virus (isolate Angola/14FA/1971) (YFV)

1 entry

Yellow fever virus (isolate Ethiopia/Couma/1961) (YFV)

1 entry

Yellow fever virus (isolate Ivory Coast/1999) (YFV)

1 entry

Yellow fever virus (isolate Ivory Coast/85-82H/1982) (YFV)

1 entry

Yellow fever virus (isolate Uganda/A7094A4/1948) (YFV)

1 entry

Yellow fever virus (strain French neurotropic vaccine FNV) (YFV)

1 entry

Yellow fever virus (strain Ghana/Asibi/1927) (YFV)

1 entry

Yellow fever virus (strain Trinidad/TRINID79A/1979) (YFV)

These structures were created with the help of Colabfold by Jason Nomburg, Nathan Price and Jennifer Doudna

(ModelArchive).

Anopheles flavivirus variant 1 taxid:1903340

Protein	ModelArchive
Fifo	ma-jd-viral-56717

Equine pegivirus 1 taxid:1307803

Protein	ModelArchive
Genome polyprotein	ma-jd-viral-08367
Genome polyprotein	ma-jd-viral-08408
Genome polyprotein	ma-jd-viral-14660
Genome polyprotein	ma-jd-viral-32707
Genome polyprotein	ma-jd-viral-32159
Genome polyprotein	ma-jd-viral-19271
Genome polyprotein	ma-jd-viral-22252
Genome polyprotein	ma-jd-viral-45539
Genome polyprotein	ma-jd-viral-38590
Genome polyprotein	ma-jd-viral-57542

New Mapoon virus taxid:499854

Protein	ModelArchive
Genome polyprotein	ma-jd-viral-08134
Genome polyprotein	ma-jd-viral-11114
Genome polyprotein	ma-jd-viral-16974
Genome polyprotein	ma-jd-viral-34627
Genome polyprotein	ma-jd-viral-32790
Genome polyprotein	ma-jd-viral-22213
Genome polyprotein	ma-jd-viral-49936
Genome polyprotein	ma-jd-viral-38197
Genome polyprotein	ma-jd-viral-38258
Genome polyprotein	ma-jd-viral-67049
Genome polyprotein	ma-jd-viral-55680
Genome polyprotein	ma-jd-viral-55697
Genome polyprotein	ma-jd-viral-63339

Tembusu virus taxid:64293

Protein	ModelArchive
Genome polyprotein	ma-jd-viral-08129
Genome polyprotein	ma-jd-viral-11120
Genome polyprotein	ma-jd-viral-16967
Genome polyprotein	ma-jd-viral-34625
Genome polyprotein	ma-jd-viral-32799
Genome polyprotein	ma-jd-viral-22218
Genome polyprotein	ma-jd-viral-49938
Genome polyprotein	ma-jd-viral-38208
Genome polyprotein	ma-jd-viral-38262
Genome polyprotein	ma-jd-viral-67047
Genome polyprotein	ma-jd-viral-55682
Genome polyprotein	ma-jd-viral-55686
Genome polyprotein	ma-jd-viral-63338

Wenling shark virus taxid:1746066

Protein	ModelArchive
Genome polyprotein	ma-jd-viral-08406
Genome polyprotein	ma-jd-viral-14668
Genome polyprotein	ma-jd-viral-19290
Genome polyprotein	ma-jd-viral-22255
Genome polyprotein	ma-jd-viral-51509
Genome polyprotein	ma-jd-viral-45770
Genome polyprotein	ma-jd-viral-40548
Genome polyprotein	ma-jd-viral-66750
Genome polyprotein	ma-jd-viral-60990
Genome polyprotein	ma-jd-viral-56947